These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 34797363)

  • 1. Elucidating microscopic events driven by GTP hydrolysis reaction in the Ras-GAP system with semi-reactive molecular dynamics simulations: the alternative role of a phosphate binding loop for mechanical energy storage.
    Kurisaki I; Tanaka S
    Phys Chem Chem Phys; 2021 Dec; 23(46):26151-26164. PubMed ID: 34797363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computational characterization of the chemical step in the GTP hydrolysis by Ras-GAP for the wild-type and G13V mutated Ras.
    Mironov VA; Khrenova MG; Lychko LA; Nemukhin AV
    Proteins; 2015 Jun; 83(6):1046-53. PubMed ID: 25820867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein.
    Kötting C; Blessenohl M; Suveyzdis Y; Goody RS; Wittinghofer A; Gerwert K
    Proc Natl Acad Sci U S A; 2006 Sep; 103(38):13911-6. PubMed ID: 16968776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Theoretical vibrational spectroscopy of intermediates and the reaction mechanism of the guanosine triphosphate hydrolysis by the protein complex Ras-GAP.
    Khrenova MG; Grigorenko BL; Nemukhin AV
    Spectrochim Acta A Mol Biomol Spectrosc; 2016 Sep; 166():68-72. PubMed ID: 27214270
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations.
    Rudack T; Xia F; Schlitter J; Kötting C; Gerwert K
    Proc Natl Acad Sci U S A; 2012 Sep; 109(38):15295-300. PubMed ID: 22949691
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modeling the role of G12V and G13V Ras mutations in the Ras-GAP-catalyzed hydrolysis reaction of guanosine triphosphate.
    Khrenova MG; Mironov VA; Grigorenko BL; Nemukhin AV
    Biochemistry; 2014 Nov; 53(45):7093-9. PubMed ID: 25339142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrolysis of Guanosine Triphosphate (GTP) by the Ras·GAP Protein Complex: Reaction Mechanism and Kinetic Scheme.
    Khrenova MG; Grigorenko BL; Kolomeisky AB; Nemukhin AV
    J Phys Chem B; 2015 Oct; 119(40):12838-45. PubMed ID: 26374425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantum chemical modeling of the GTP hydrolysis by the RAS-GAP protein complex.
    Topol IA; Cachau RE; Nemukhin AV; Grigorenko BL; Burt SK
    Biochim Biophys Acta; 2004 Jul; 1700(1):125-36. PubMed ID: 15210132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ras catalyzes GTP hydrolysis by shifting negative charges from gamma- to beta-phosphate as revealed by time-resolved FTIR difference spectroscopy.
    Allin C; Gerwert K
    Biochemistry; 2001 Mar; 40(10):3037-46. PubMed ID: 11258917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reaction Mechanism of Guanosine Triphosphate Hydrolysis by the Vision-Related Protein Complex Arl3-RP2.
    Khrenova MG; Kots ED; Nemukhin AV
    J Phys Chem B; 2016 Apr; 120(16):3873-9. PubMed ID: 27043216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. gamma-phosphate protonation and pH-dependent unfolding of the Ras.GTP.Mg2+ complex: a vibrational spectroscopy study.
    Cheng H; Sukal S; Callender R; Leyh TS
    J Biol Chem; 2001 Mar; 276(13):9931-5. PubMed ID: 11124953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
    Shutes A; Der CJ
    Methods Enzymol; 2006; 407():9-22. PubMed ID: 16757310
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Diversity of mechanisms in Ras-GAP catalysis of guanosine triphosphate hydrolysis revealed by molecular modeling.
    Grigorenko BL; Kots ED; Nemukhin AV
    Org Biomol Chem; 2019 May; 17(19):4879-4891. PubMed ID: 31041977
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of Guanosine Triphosphate Hydrolysis by the Visual Proteins Arl3-RP2: Free Energy Reaction Profiles Computed with Ab Initio Type QM/MM Potentials.
    Khrenova MG; Bulavko ES; Mulashkin FD; Nemukhin AV
    Molecules; 2021 Jun; 26(13):. PubMed ID: 34208932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations.
    Rudack T; Xia F; Schlitter J; Kötting C; Gerwert K
    Biophys J; 2012 Jul; 103(2):293-302. PubMed ID: 22853907
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational study of a transition state analog of phosphoryl transfer in the Ras-RasGAP complex: AlF(x) versus MgF3-.
    Grigorenko BL; Nemukhin AV; Cachau RE; Topol IA; Burt SK
    J Mol Model; 2005 Nov; 11(6):503-8. PubMed ID: 16052311
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Free energy simulations of a GTPase: GTP and GDP binding to archaeal initiation factor 2.
    Satpati P; Clavaguéra C; Ohanessian G; Simonson T
    J Phys Chem B; 2011 May; 115(20):6749-63. PubMed ID: 21534562
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.
    Maegley KA; Admiraal SJ; Herschlag D
    Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8160-6. PubMed ID: 8710841
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.