BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 34800886)

  • 1. Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism.
    Elshemy HAH; Zaki MA; Mahmoud AM; Khan SI; Chittiboyina AG; Kamal AM
    Bioorg Chem; 2022 Jan; 118():105475. PubMed ID: 34800886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
    Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant cancer cells, dual β-tubulin/c-Src inhibition, cell cycle arrest and apoptosis induction.
    Abdelall EKA; A H Elshemy H; Labib MB; E A Mohamed F
    Bioorg Chem; 2022 Mar; 120():105591. PubMed ID: 34998122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents.
    Madadi NR; Penthala NR; Ketkar A; Eoff RL; Trujullo-Alonso V; Guzman ML; Crooks PA
    Anticancer Agents Med Chem; 2018; 18(4):556-564. PubMed ID: 28403783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene.
    Alblewi FF; Okasha RM; Hritani ZM; Mohamed HM; El-Nassag MAA; Halawa AH; Mora A; Fouda AM; Assiri MA; Al-Dies AM; Afifi TH; El-Agrody AM
    Bioorg Chem; 2019 Jun; 87():560-571. PubMed ID: 30928878
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities.
    Fallah-Tafti A; Tiwari R; Shirazi AN; Akbarzadeh T; Mandal D; Shafiee A; Parang K; Foroumadi A
    Med Chem; 2011 Sep; 7(5):466-72. PubMed ID: 21801146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
    Qin J; Qu S; Zhu K; Cheng Y; Pan G; Jing W; Liu X; Sun X; Liu L
    Bioorg Med Chem; 2021 Feb; 32():116003. PubMed ID: 33461148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of antitumor activity of 9-methoxy-1H-benzo[f]chromene derivatives.
    Elgaafary M; Lehner J; Fouda AM; Hamed A; Ulrich J; Simmet T; Syrovets T; El-Agrody AM
    Bioorg Chem; 2021 Nov; 116():105402. PubMed ID: 34670333
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
    Kemnitzer W; Drewe J; Jiang S; Zhang H; Wang Y; Zhao J; Jia S; Herich J; Labreque D; Storer R; Meerovitch K; Bouffard D; Rej R; Denis R; Blais C; Lamothe S; Attardo G; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
    J Med Chem; 2004 Dec; 47(25):6299-310. PubMed ID: 15566300
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, antitumor screening and cell cycle analysis of novel benzothieno[3,2-b]pyran derivatives.
    Zaher AF; Abuel-Maaty SM; El-Nassan HB; Amer SA; Abdelghany TM
    J Enzyme Inhib Med Chem; 2016; 31(sup4):145-153. PubMed ID: 27590401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.
    Abdelatef SA; El-Saadi MT; Amin NH; Abdelazeem AH; Omar HA; Abdellatif KRA
    Eur J Med Chem; 2018 Apr; 150():567-578. PubMed ID: 29549841
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators.
    Al-Oudat BA; Alqudah MA; Audat SA; Al-Balas QA; El-Elimat T; Hassan MA; Frhat IN; Azaizeh MM
    Drug Des Devel Ther; 2019; 13():423-433. PubMed ID: 30774307
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers.
    Ghorab MM; Alsaid MS; Al-Ansary GH; Abdel-Latif GA; Abou El Ella DA
    Eur J Med Chem; 2016 Nov; 124():946-958. PubMed ID: 27770735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2H-chromene derivatives as potent anti-breast cancer agents.
    Rahmani-Nezhad S; Safavi M; Pordeli M; Ardestani SK; Khosravani L; Pourshojaei Y; Mahdavi M; Emami S; Foroumadi A; Shafiee A
    Eur J Med Chem; 2014 Oct; 86():562-9. PubMed ID: 25216378
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and Anticancer Activity of Novel Chromene Derivatives, Chromeno[2,3-d][1,3]Oxazines, and Chromeno[2,3-d]Pyrimidines.
    Yousif MNM; Fathy U; Yousif NM
    Med Chem; 2023; 19(6):578-585. PubMed ID: 36573048
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
    Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
    Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of novel 1,2,3-triazole/isoxazole functionalized 2H-Chromene derivatives and their cytotoxic activity.
    Ratnakar Reddy K; Sambasiva Rao P; Jitender Dev G; Poornachandra Y; Ganesh Kumar C; Shanthan Rao P; Narsaiah B
    Bioorg Med Chem Lett; 2014 Apr; 24(7):1661-3. PubMed ID: 24641975
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel chromene derivatives of expected antitumor activity.
    Kandeel MM; Kamal AM; Abdelall EK; Elshemy HA
    Eur J Med Chem; 2013 Jan; 59():183-93. PubMed ID: 23220647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.