BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 34801828)

  • 1. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
    Maksimainen MM; Murthy S; Sowa ST; Galera-Prat A; Rolina E; Heiskanen JP; Lehtiö L
    Bioorg Med Chem; 2021 Dec; 52():116511. PubMed ID: 34801828
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors.
    Venkannagari H; Fallarero A; Feijs KL; Lüscher B; Lehtiö L
    Eur J Pharm Sci; 2013 May; 49(2):148-56. PubMed ID: 23485441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14.
    Holechek J; Lease R; Thorsell AG; Karlberg T; McCadden C; Grant R; Keen A; Callahan E; Schüler H; Ferraris D
    Bioorg Med Chem Lett; 2018 Jun; 28(11):2050-2054. PubMed ID: 29748053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective inhibition of PARP10 using a chemical genetics strategy.
    Morgan RK; Carter-O'Connell I; Cohen MS
    Bioorg Med Chem Lett; 2015 Nov; 25(21):4770-4773. PubMed ID: 26231158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Towards small molecule inhibitors of mono-ADP-ribosyltransferases.
    Ekblad T; Lindgren AE; Andersson CD; Caraballo R; Thorsell AG; Karlberg T; Spjut S; Linusson A; Schüler H; Elofsson M
    Eur J Med Chem; 2015 May; 95():546-51. PubMed ID: 25847771
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10.
    Korn P; Classen A; Murthy S; Guareschi R; Maksimainen MM; Lippok BE; Galera-Prat A; Sowa ST; Voigt C; Rossetti G; Lehtiö L; Bolm C; Lüscher B
    ChemistryOpen; 2021 Oct; 10(10):939-948. PubMed ID: 34145784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15.
    Nizi MG; Maksimainen MM; Murthy S; Massari S; Alaviuhkola J; Lippok BE; Sowa ST; Galera-Prat A; Prunskaite-Hyyryläinen R; Lüscher B; Korn P; Lehtiö L; Tabarrini O
    Eur J Med Chem; 2022 Jul; 237():114362. PubMed ID: 35500474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.
    Murthy S; Desantis J; Verheugd P; Maksimainen MM; Venkannagari H; Massari S; Ashok Y; Obaji E; Nkizinkinko Y; Lüscher B; Tabarrini O; Lehtiö L
    Eur J Med Chem; 2018 Aug; 156():93-102. PubMed ID: 30006177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage.
    Venkannagari H; Verheugd P; Koivunen J; Haikarainen T; Obaji E; Ashok Y; Narwal M; Pihlajaniemi T; Lüscher B; Lehtiö L
    Cell Chem Biol; 2016 Oct; 23(10):1251-1260. PubMed ID: 27667561
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structures of the catalytic domain of human PARP15 in complex with small molecule inhibitors.
    Zhou X; Yang Y; Xu Q; Zhou H; Zhong F; Deng J; Zhang J; Li J
    Biochem Biophys Res Commun; 2022 Sep; 622():93-100. PubMed ID: 35843099
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein.
    Karlberg T; Klepsch M; Thorsell AG; Andersson CD; Linusson A; Schüler H
    J Biol Chem; 2015 Mar; 290(12):7336-44. PubMed ID: 25635049
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14.
    Upton K; Meyers M; Thorsell AG; Karlberg T; Holechek J; Lease R; Schey G; Wolf E; Lucente A; Schüler H; Ferraris D
    Bioorg Med Chem Lett; 2017 Jul; 27(13):2907-2911. PubMed ID: 28495083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol.
    Ekblad T; Verheugd P; Lindgren AE; Nyman T; Elofsson M; Schüler H
    SLAS Discov; 2018 Apr; 23(4):353-362. PubMed ID: 29316839
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.
    Kleine H; Poreba E; Lesniewicz K; Hassa PO; Hottiger MO; Litchfield DW; Shilton BH; Lüscher B
    Mol Cell; 2008 Oct; 32(1):57-69. PubMed ID: 18851833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Simple, Sensitive, and Generalizable Plate Assay for Screening PARP Inhibitors.
    Kirby IT; Morgan RK; Cohen MS
    Methods Mol Biol; 2018; 1813():245-252. PubMed ID: 30097873
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [1,2,4]Triazolo[3,4-
    Murthy S; Nizi MG; Maksimainen MM; Massari S; Alaviuhkola J; Lippok BE; Vagaggini C; Sowa ST; Galera-Prat A; Ashok Y; Venkannagari H; Prunskaite-Hyyryläinen R; Dreassi E; Lüscher B; Korn P; Tabarrini O; Lehtiö L
    J Med Chem; 2023 Jan; 66(2):1301-1320. PubMed ID: 36598465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PARP10 Multi-Site Auto- and Histone MARylation Visualized by Acid-Urea Gel Electrophoresis.
    García-Saura AG; Schüler H
    Cells; 2021 Mar; 10(3):. PubMed ID: 33804157
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role of intracellular mono-ADP-ribosylation in cancer biology.
    Scarpa ES; Fabrizio G; Di Girolamo M
    FEBS J; 2013 Aug; 280(15):3551-62. PubMed ID: 23590234
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP.
    Frigon L; Pascal JM
    Nucleic Acids Res; 2023 Dec; 51(22):12492-12507. PubMed ID: 37971310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SnapShot: ADP-Ribosylation Signaling.
    Hottiger MO
    Mol Cell; 2015 Jun; 58(6):1134-1134.e1. PubMed ID: 26091348
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.