BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 34806400)

  • 1. Tetrahydrobiopterin in Cell Function and Death Mechanisms.
    Vasquez-Vivar J; Shi Z; Tan S
    Antioxid Redox Signal; 2022 Jul; 37(1-3):171-183. PubMed ID: 34806400
    [No Abstract]   [Full Text] [Related]  

  • 2. Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.
    McNeill E; Crabtree MJ; Sahgal N; Patel J; Chuaiphichai S; Iqbal AJ; Hale AB; Greaves DR; Channon KM
    Free Radic Biol Med; 2015 Feb; 79():206-16. PubMed ID: 25451639
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.
    Gross SS; Levi R
    J Biol Chem; 1992 Dec; 267(36):25722-9. PubMed ID: 1281471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
    Crabtree MJ; Tatham AL; Al-Wakeel Y; Warrick N; Hale AB; Cai S; Channon KM; Alp NJ
    J Biol Chem; 2009 Jan; 284(2):1136-44. PubMed ID: 19011239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
    Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
    J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
    Sugiyama T; Levy BD; Michel T
    J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
    Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
    Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mast cell tetrahydrobiopterin contributes to itch in mice.
    Zschiebsch K; Fischer C; Wilken-Schmitz A; Geisslinger G; Channon K; Watschinger K; Tegeder I
    J Cell Mol Med; 2019 Feb; 23(2):985-1000. PubMed ID: 30450838
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells.
    Hwang O; Baker H; Gross S; Joh TH
    Synapse; 1998 Feb; 28(2):140-53. PubMed ID: 9450514
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
    Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
    Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.
    Crabtree MJ; Channon KM
    Nitric Oxide; 2011 Aug; 25(2):81-8. PubMed ID: 21550412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carboxy-PTIO increases the tetrahydrobiopterin level in mouse brain microvascular endothelial cells.
    Shimizu S; Ishii M; Iwasaki M; Shiota K; Yamamoto T; Kiuchi Y
    Jpn J Pharmacol; 2001 Sep; 87(1):51-60. PubMed ID: 11676198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin 1 beta-stimulated rat glomerular mesangial cells.
    Mühl H; Pfeilschifter J
    Kidney Int; 1994 Nov; 46(5):1302-6. PubMed ID: 7531790
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tetrahydrobiopterin availability, nitric oxide metabolism and glutathione status in the hph-1 mouse; implications for the pathogenesis and treatment of tetrahydrobiopterin deficiency states.
    Lam AA; Hyland K; Heales SJ
    J Inherit Metab Dis; 2007 Apr; 30(2):256-62. PubMed ID: 17242981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
    Chuaiphichai S; Crabtree MJ; Mcneill E; Hale AB; Trelfa L; Channon KM; Douglas G
    Br J Pharmacol; 2017 Apr; 174(8):657-671. PubMed ID: 28128438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of tetrahydrobiopterin synthesis in rat cardiac myocytes: impact on cytokine-induced NO generation.
    Kasai K; Hattori Y; Banba N; Hattori S; Motohashi S; Shimoda S; Nakanishi N; Gross SS
    Am J Physiol; 1997 Aug; 273(2 Pt 2):H665-72. PubMed ID: 9277482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.
    Benson MA; Batchelor H; Chuaiphichai S; Bailey J; Zhu H; Stuehr DJ; Bhattacharya S; Channon KM; Crabtree MJ
    J Biol Chem; 2013 Oct; 288(41):29836-45. PubMed ID: 23965989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production.
    Sethumadhavan S; Whitsett J; Bennett B; Ionova IA; Pieper GM; Vasquez-Vivar J
    Free Radic Biol Med; 2016 Apr; 93():1-11. PubMed ID: 26826575
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
    Chuaiphichai S; McNeill E; Douglas G; Crabtree MJ; Bendall JK; Hale AB; Alp NJ; Channon KM
    Hypertension; 2014 Sep; 64(3):530-40. PubMed ID: 24777984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
    Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
    Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.