BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 34810230)

  • 1. Presenilin/γ-Secretase Activity Is Located in Acidic Compartments of Live Neurons.
    Maesako M; Houser MCQ; Turchyna Y; Wolfe MS; Berezovska O
    J Neurosci; 2022 Jan; 42(1):145-154. PubMed ID: 34810230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In-Depth Characterization of Endo-Lysosomal Aβ in Intact Neurons.
    McKendell AK; Houser MCQ; Mitchell SPC; Wolfe MS; Berezovska O; Maesako M
    Biosensors (Basel); 2022 Aug; 12(8):. PubMed ID: 36005059
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production.
    Gerber H; Wu F; Dimitrov M; Garcia Osuna GM; Fraering PC
    J Biol Chem; 2017 Mar; 292(9):3751-3767. PubMed ID: 28096459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein.
    Cupers P; Bentahir M; Craessaerts K; Orlans I; Vanderstichele H; Saftig P; De Strooper B; Annaert W
    J Cell Biol; 2001 Aug; 154(4):731-40. PubMed ID: 11502763
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane.
    Pasternak SH; Bagshaw RD; Guiral M; Zhang S; Ackerley CA; Pak BJ; Callahan JW; Mahuran DJ
    J Biol Chem; 2003 Jul; 278(29):26687-94. PubMed ID: 12736250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.
    Lauritzen I; Pardossi-Piquard R; Bourgeois A; Pagnotta S; Biferi MG; Barkats M; Lacor P; Klein W; Bauer C; Checler F
    Acta Neuropathol; 2016 Aug; 132(2):257-276. PubMed ID: 27138984
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Turnover of C99 is controlled by a crosstalk between ERAD and ubiquitin-independent lysosomal degradation in human neuroglioma cells.
    Bustamante HA; Rivera-Dictter A; Cavieres VA; Muñoz VC; González A; Lin Y; Mardones GA; Burgos PV
    PLoS One; 2013; 8(12):e83096. PubMed ID: 24376644
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Limited Substrate Specificity of PS/γ-Secretase Is Supported by Novel Multiplexed FRET Analysis in Live Cells.
    Houser MCQ; Turchyna Y; Perrin F; Chibnik L; Berezovska O; Maesako M
    Biosensors (Basel); 2021 May; 11(6):. PubMed ID: 34073182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilin 1 stabilizes the C-terminal fragment of the amyloid precursor protein independently of gamma-secretase activity.
    Pitsi D; Octave JN
    J Biol Chem; 2004 Jun; 279(24):25333-8. PubMed ID: 15087467
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
    Barthet G; Shioi J; Shao Z; Ren Y; Georgakopoulos A; Robakis NK
    FASEB J; 2011 Sep; 25(9):2937-46. PubMed ID: 21597003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons.
    Roselli S; Satir TM; Camacho R; Fruhwürth S; Bergström P; Zetterberg H; Agholme L
    Cell Mol Neurobiol; 2023 Oct; 43(7):3653-3668. PubMed ID: 37355492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endosome and Lysosome Membrane Properties Functionally Link to γ-Secretase in Live/Intact Cells.
    Houser MCQ; Mitchell SPC; Sinha P; Lundin B; Berezovska O; Maesako M
    Sensors (Basel); 2023 Feb; 23(5):. PubMed ID: 36904854
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin.
    Schmidt FC; Fitz K; Feilen LP; Okochi M; Steiner H; Langosch D
    J Biol Chem; 2023 May; 299(5):104626. PubMed ID: 36944398
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The
    Tan JZA; Gleeson PA
    J Biol Chem; 2019 Feb; 294(5):1618-1631. PubMed ID: 30545942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells.
    Kokawa A; Ishihara S; Fujiwara H; Nobuhara M; Iwata M; Ihara Y; Funamoto S
    Acta Neuropathol Commun; 2015 Nov; 3():66. PubMed ID: 26531305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells.
    Houser MC; Hou SS; Perrin F; Turchyna Y; Bacskai BJ; Berezovska O; Maesako M
    Sensors (Basel); 2020 Oct; 20(21):. PubMed ID: 33105735
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage.
    Li S; Deng J; Hou H; Tian J; Giunta B; Wang Y; Sawmiller D; Smith A; Sanberg PR; Obregon D; Mori T; Tan J
    Cell Death Dis; 2014 Aug; 5(8):e1374. PubMed ID: 25118934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.