BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 34815381)

  • 1. HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells.
    Da C; Pu J; Liu Z; Wei J; Qu Y; Wu Y; Shi B; Yang J; He N; Hou P
    Signal Transduct Target Ther; 2021 Nov; 6(1):399. PubMed ID: 34815381
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity.
    Kumar B; Roy A; Asha K; Sharma-Walia N; Ansari MA; Chandran B
    J Virol; 2019 May; 93(9):. PubMed ID: 30787155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.
    Rotblat B; Southwell AL; Ehrnhoefer DE; Skotte NH; Metzler M; Franciosi S; Leprivier G; Somasekharan SP; Barokas A; Deng Y; Tang T; Mathers J; Cetinbas N; Daugaard M; Kwok B; Li L; Carnie CJ; Fink D; Nitsch R; Galpin JD; Ahern CA; Melino G; Penninger JM; Hayden MR; Sorensen PH
    Proc Natl Acad Sci U S A; 2014 Feb; 111(8):3032-7. PubMed ID: 24516159
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
    Chen TY; Zheng SK
    In Vitro Cell Dev Biol Anim; 2022 Oct; 58(9):830-839. PubMed ID: 36251153
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.
    Ehrnhoefer DE; Southwell AL; Sivasubramanian M; Qiu X; Villanueva EB; Xie Y; Waltl S; Anderson L; Fazeli A; Casal L; Felczak B; Tsang M; Hayden MR
    Hum Mol Genet; 2018 Jan; 27(2):239-253. PubMed ID: 29121340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2.
    Yin P; Wu Y; Long X; Zhu S; Chen S; Lu F; Lin K; Xu J
    Aging (Albany NY); 2023 Dec; 15(23):13888-13900. PubMed ID: 38070140
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HACE1 is a potential tumor suppressor in osteosarcoma.
    El-Naggar AM; Clarkson PW; Negri GL; Turgu B; Zhang F; Anglesio MS; Sorensen PH
    Cell Death Dis; 2019 Jan; 10(1):21. PubMed ID: 30622235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.
    Sheikh T; Gupta P; Gowda P; Patrick S; Sen E
    J Biol Chem; 2018 Mar; 293(13):4767-4777. PubMed ID: 29414774
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Effect of Dimethyl Fumarate (DMF) on T-cell Acute Lymphoblastic Leukemia].
    Xu JG; Cheng Q; Zhang GH; Kong LP; Li L; Liu KG; Wu JY; Zhang QR
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2022 Feb; 30(1):1-5. PubMed ID: 35123595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
    Lo SC; Hannink M
    Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.
    Kanamori M; Higa T; Sonoda Y; Murakami S; Dodo M; Kitamura H; Taguchi K; Shibata T; Watanabe M; Suzuki H; Shibahara I; Saito R; Yamashita Y; Kumabe T; Yamamoto M; Motohashi H; Tominaga T
    Neuro Oncol; 2015 Apr; 17(4):555-65. PubMed ID: 25304134
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney.
    Anglesio MS; Evdokimova V; Melnyk N; Zhang L; Fernandez CV; Grundy PE; Leach S; Marra MA; Brooks-Wilson AR; Penninger J; Sorensen PH
    Hum Mol Genet; 2004 Sep; 13(18):2061-74. PubMed ID: 15254018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Seven in absentia homolog 2 (Siah2) protein is a regulator of NF-E2-related factor 2 (Nrf2).
    Baba K; Morimoto H; Imaoka S
    J Biol Chem; 2013 Jun; 288(25):18393-405. PubMed ID: 23645672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A positive feedback loop of miR-30a-5p-WWP1-NF-κB in the regulation of glioma development.
    Zhao P; Wang M; An J; Sun H; Li T; Li D
    Int J Biochem Cell Biol; 2019 Jul; 112():39-49. PubMed ID: 30978403
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sp1 is a substrate of Keap1 and regulates the activity of CRL4A
    Siswanto FM; Oguro A; Imaoka S
    J Biol Chem; 2021; 296():100704. PubMed ID: 33895141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction.
    Cetinbas N; Daugaard M; Mullen AR; Hajee S; Rotblat B; Lopez A; Li A; DeBerardinis RJ; Sorensen PH
    Oncogene; 2015 Jul; 34(30):4005-10. PubMed ID: 25284589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression.
    Li JC; Chang X; Chen Y; Li XZ; Zhang XL; Yang SM; Hu CJ; Zhang H
    Curr Drug Targets; 2019; 20(10):1018-1028. PubMed ID: 30827236
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
    Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH
    Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E3 ligase TRIM15 facilitates non-small cell lung cancer progression through mediating Keap1-Nrf2 signaling pathway.
    Liang M; Wang L; Sun Z; Chen X; Wang H; Qin L; Zhao W; Geng B
    Cell Commun Signal; 2022 May; 20(1):62. PubMed ID: 35534896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitin-independent proteasomal degradation of Spindlin-1 by the E3 ligase HACE1 contributes to cell-cell adhesion.
    Palicharla VR; Gupta D; Bhattacharya D; Maddika S
    FEBS Lett; 2021 Feb; 595(4):491-506. PubMed ID: 33421097
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.