243 related articles for article (PubMed ID: 34822164)
1. Expanding role of PI5P4Ks in cancer: A promising druggable target.
Arora GK; Palamiuc L; Emerling BM
FEBS Lett; 2022 Jan; 596(1):3-16. PubMed ID: 34822164
[TBL] [Abstract][Full Text] [Related]
2. PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.
Ravi A; Palamiuc L; Loughran RM; Triscott J; Arora GK; Kumar A; Tieu V; Pauli C; Reist M; Lew RJ; Houlihan SL; Fellmann C; Metallo C; Rubin MA; Emerling BM
Dev Cell; 2021 Jun; 56(11):1661-1676.e10. PubMed ID: 33984270
[TBL] [Abstract][Full Text] [Related]
3. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors.
Sivakumaren SC; Shim H; Zhang T; Ferguson FM; Lundquist MR; Browne CM; Seo HS; Paddock MN; Manz TD; Jiang B; Hao MF; Krishnan P; Wang DG; Yang TJ; Kwiatkowski NP; Ficarro SB; Cunningham JM; Marto JA; Dhe-Paganon S; Cantley LC; Gray NS
Cell Chem Biol; 2020 May; 27(5):525-537.e6. PubMed ID: 32130941
[TBL] [Abstract][Full Text] [Related]
4. Crucial Players for Inter-Organelle Communication: PI5P4Ks and Their Lipid Product PI-4,5-P
Ravi A; Palamiuc L; Emerling BM
Front Cell Dev Biol; 2021; 9():791758. PubMed ID: 35071233
[TBL] [Abstract][Full Text] [Related]
5. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Emerling BM; Hurov JB; Poulogiannis G; Tsukazawa KS; Choo-Wing R; Wulf GM; Bell EL; Shim HS; Lamia KA; Rameh LE; Bellinger G; Sasaki AT; Asara JM; Yuan X; Bullock A; Denicola GM; Song J; Brown V; Signoretti S; Cantley LC
Cell; 2013 Nov; 155(4):844-57. PubMed ID: 24209622
[TBL] [Abstract][Full Text] [Related]
6. Targeting phosphoinositide signaling in cancer: relevant techniques to study lipids and novel avenues for therapeutic intervention.
Llorente A; Loughran RM; Emerling BM
Front Cell Dev Biol; 2023; 11():1297355. PubMed ID: 37954209
[TBL] [Abstract][Full Text] [Related]
7. Exploring phosphatidylinositol 5-phosphate 4-kinase function.
Bulley SJ; Clarke JH; Droubi A; Giudici ML; Irvine RF
Adv Biol Regul; 2015 Jan; 57():193-202. PubMed ID: 25311266
[TBL] [Abstract][Full Text] [Related]
8. Phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ), a lipid signalling enigma.
Giudici ML; Clarke JH; Irvine RF
Adv Biol Regul; 2016 May; 61():47-50. PubMed ID: 26710750
[TBL] [Abstract][Full Text] [Related]
9. The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.
Carricaburu V; Lamia KA; Lo E; Favereaux L; Payrastre B; Cantley LC; Rameh LE
Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9867-72. PubMed ID: 12897244
[TBL] [Abstract][Full Text] [Related]
10. Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.
Clarke JH; Irvine RF
Biochem J; 2013 Aug; 454(1):49-57. PubMed ID: 23758345
[TBL] [Abstract][Full Text] [Related]
11. PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.
Wang DG; Paddock MN; Lundquist MR; Sun JY; Mashadova O; Amadiume S; Bumpus TW; Hodakoski C; Hopkins BD; Fine M; Hill A; Yang TJ; Baskin JM; Dow LE; Cantley LC
Cell Rep; 2019 May; 27(7):1991-2001.e5. PubMed ID: 31091439
[TBL] [Abstract][Full Text] [Related]
12. Discovery and Structure-Activity Relationship Study of (
Manz TD; Sivakumaren SC; Ferguson FM; Zhang T; Yasgar A; Seo HS; Ficarro SB; Card JD; Shim H; Miduturu CV; Simeonov A; Shen M; Marto JA; Dhe-Paganon S; Hall MD; Cantley LC; Gray NS
J Med Chem; 2020 May; 63(9):4880-4895. PubMed ID: 32298120
[TBL] [Abstract][Full Text] [Related]
13. Lipid kinases PIP5Ks and PIP4Ks: potential drug targets for breast cancer.
Jin Y; Xue J
Front Oncol; 2023; 13():1323897. PubMed ID: 38156113
[TBL] [Abstract][Full Text] [Related]
14. In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.
Bulley SJ; Droubi A; Clarke JH; Anderson KE; Stephens LR; Hawkins PT; Irvine RF
Proc Natl Acad Sci U S A; 2016 Sep; 113(38):10571-6. PubMed ID: 27601656
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Chen S; Chandra Tjin C; Gao X; Xue Y; Jiao H; Zhang R; Wu M; He Z; Ellman J; Ha Y
Proc Natl Acad Sci U S A; 2021 May; 118(21):. PubMed ID: 34001596
[TBL] [Abstract][Full Text] [Related]
16. Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage.
Poli A; Zaurito AE; Abdul-Hamid S; Fiume R; Faenza I; Divecha N
Int J Mol Sci; 2019 Apr; 20(9):. PubMed ID: 31035587
[TBL] [Abstract][Full Text] [Related]
17. The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site.
Clarke JH; Giudici ML; Burke JE; Williams RL; Maloney DJ; Marugan J; Irvine RF
Biochem J; 2015 Mar; 466(2):359-67. PubMed ID: 25495341
[TBL] [Abstract][Full Text] [Related]
18. Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane PIP
Sharma S; Mathre S; Ramya V; Shinde D; Raghu P
Cell Rep; 2019 May; 27(7):1979-1990.e7. PubMed ID: 31091438
[TBL] [Abstract][Full Text] [Related]
19. 25 Years of PI5P.
Rameh LE; Blind RD
Front Cell Dev Biol; 2023; 11():1272911. PubMed ID: 37849742
[TBL] [Abstract][Full Text] [Related]
20. Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress.
Droubi A; Bulley SJ; Clarke JH; Irvine RF
Biochem J; 2016 Jul; 473(14):2155-63. PubMed ID: 27208178
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
