BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 34831348)

  • 1. Activation Mechanisms of the VPS34 Complexes.
    Ohashi Y
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831348
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
    Itakura E; Kishi C; Inoue K; Mizushima N
    Mol Biol Cell; 2008 Dec; 19(12):5360-72. PubMed ID: 18843052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.
    Zhong Y; Morris DH; Jin L; Patel MS; Karunakaran SK; Fu YJ; Matuszak EA; Weiss HL; Chait BT; Wang QJ
    J Biol Chem; 2014 Sep; 289(38):26021-26037. PubMed ID: 25086043
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
    McKnight NC; Zhong Y; Wold MS; Gong S; Phillips GR; Dou Z; Zhao Y; Heintz N; Zong WX; Yue Z
    PLoS Genet; 2014 Oct; 10(10):e1004626. PubMed ID: 25275521
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
    Tremel S; Ohashi Y; Morado DR; Bertram J; Perisic O; Brandt LTL; von Wrisberg MK; Chen ZA; Maslen SL; Kovtun O; Skehel M; Rappsilber J; Lang K; Munro S; Briggs JAG; Williams RL
    Nat Commun; 2021 Mar; 12(1):1564. PubMed ID: 33692360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.
    Rostislavleva K; Soler N; Ohashi Y; Zhang L; Pardon E; Burke JE; Masson GR; Johnson C; Steyaert J; Ktistakis NT; Williams RL
    Science; 2015 Oct; 350(6257):aac7365. PubMed ID: 26450213
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.
    Thoresen SB; Pedersen NM; Liestøl K; Stenmark H
    Exp Cell Res; 2010 Dec; 316(20):3368-78. PubMed ID: 20643123
    [TBL] [Abstract][Full Text] [Related]  

  • 8. VPS34 complexes from a structural perspective.
    Ohashi Y; Tremel S; Williams RL
    J Lipid Res; 2019 Feb; 60(2):229-241. PubMed ID: 30397185
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Class III phosphatidylinositol 3-kinase complex I subunit NRBF2/Atg38 - from cell and structural biology to health and disease.
    Ohashi Y
    Autophagy; 2021 Dec; 17(12):3897-3907. PubMed ID: 33459128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.
    Ohashi Y; Soler N; García Ortegón M; Zhang L; Kirsten ML; Perisic O; Masson GR; Burke JE; Jakobi AJ; Apostolakis AA; Johnson CM; Ohashi M; Ktistakis NT; Sachse C; Williams RL
    Autophagy; 2016 Nov; 12(11):2129-2144. PubMed ID: 27630019
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Atg14 and UVRAG: mutually exclusive subunits of mammalian Beclin 1-PI3K complexes.
    Itakura E; Mizushima N
    Autophagy; 2009 May; 5(4):534-6. PubMed ID: 19223761
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
    Zhong Y; Wang QJ; Li X; Yan Y; Backer JM; Chait BT; Heintz N; Yue Z
    Nat Cell Biol; 2009 Apr; 11(4):468-76. PubMed ID: 19270693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NRBF2 regulates macroautophagy as a component of Vps34 Complex I.
    Cao Y; Wang Y; Abi Saab WF; Yang F; Pessin JE; Backer JM
    Biochem J; 2014 Jul; 461(2):315-22. PubMed ID: 24785657
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity.
    Araki Y; Ku WC; Akioka M; May AI; Hayashi Y; Arisaka F; Ishihama Y; Ohsumi Y
    J Cell Biol; 2013 Oct; 203(2):299-313. PubMed ID: 24165940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The class III phosphatidylinositol 3-kinase Vps34 in Saccharomyces cerevisiae.
    Reidick C; Boutouja F; Platta HW
    Biol Chem; 2017 May; 398(5-6):677-685. PubMed ID: 27935849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I.
    Pavlinov I; Salkovski M; Aldrich LN
    J Am Chem Soc; 2020 May; 142(18):8174-8182. PubMed ID: 32320221
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK.
    Zhao Y; Wang Q; Qiu G; Zhou S; Jing Z; Wang J; Wang W; Cao J; Han K; Cheng Q; Shen B; Chen Y; Zhang WJ; Ma Y; Zhang J
    Cell Rep; 2015 Nov; 13(7):1407-1417. PubMed ID: 26549445
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.
    Bago R; Malik N; Munson MJ; Prescott AR; Davies P; Sommer E; Shpiro N; Ward R; Cross D; Ganley IG; Alessi DR
    Biochem J; 2014 Nov; 463(3):413-27. PubMed ID: 25177796
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy.
    Kim J; Kim YC; Fang C; Russell RC; Kim JH; Fan W; Liu R; Zhong Q; Guan KL
    Cell; 2013 Jan; 152(1-2):290-303. PubMed ID: 23332761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1.
    Hirsch DS; Shen Y; Dokmanovic M; Yu J; Mohan N; Elzarrad MK; Wu WJ
    Cell Signal; 2014 Jun; 26(6):1258-68. PubMed ID: 24582588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.