BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 34844996)

  • 1. Exposure to High-Altitude Environment Is Associated with Drug Transporters Change: microRNA-873-5p-Mediated Alteration of Function and Expression Levels of Drug Transporters under Hypoxia.
    Duan Y; Bai X; Yang J; Zhou Y; Gu W; Liu G; Wang Q; Zhu J; La L; Li X
    Drug Metab Dispos; 2022 Feb; 50(2):174-186. PubMed ID: 34844996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.
    Arias A; Rigalli JP; Villanueva SS; Ruiz ML; Luquita MG; Perdomo VG; Vore M; Catania VA; Mottino AD
    Toxicology; 2014 Jun; 320():46-55. PubMed ID: 24685904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.
    Chisaki I; Kobayashi M; Itagaki S; Hirano T; Iseki K
    Biochim Biophys Acta; 2009 Nov; 1788(11):2396-403. PubMed ID: 19728987
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells.
    Sampson KE; Brinker A; Pratt J; Venkatraman N; Xiao Y; Blasberg J; Steiner T; Bourner M; Thompson DC
    Drug Metab Dispos; 2015 Feb; 43(2):199-207. PubMed ID: 25388687
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells.
    Jin G; Li Y; Zhu Y; Du L; Yan J; Yang Q
    Cell Biol Toxicol; 2016 Dec; 32(6):483-497. PubMed ID: 27394416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells.
    Seithel A; Karlsson J; Hilgendorf C; Björquist A; Ungell AL
    Eur J Pharm Sci; 2006 Jul; 28(4):291-9. PubMed ID: 16704924
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: a strategy to assess the interaction of a new chemical entity with P-gp, BCRP, and MRP2.
    Mease K; Sane R; Podila L; Taub ME
    J Pharm Sci; 2012 May; 101(5):1888-97. PubMed ID: 22359351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications.
    Naseem A; Pal A; Gowan S; Asad Y; Donovan A; Temesszentandrási-Ambrus C; Kis E; Gaborik Z; Bhalay G; Raynaud F
    Cells; 2022 Oct; 11(20):. PubMed ID: 36291153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.
    Marchetti S; Oostendorp RL; Pluim D; van Eijndhoven M; van Tellingen O; Schinkel AH; Versace R; Beijnen JH; Mazzanti R; Schellens JH
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3307-13. PubMed ID: 18089724
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
    Dahan A; Amidon GL
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells.
    Fan J; Maeng HJ; Du Y; Kwan D; Pang KS
    Eur J Pharm Sci; 2011 Jan; 42(1-2):19-29. PubMed ID: 20955791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human.
    Kalgutkar AS; Feng B; Nguyen HT; Frederick KS; Campbell SD; Hatch HL; Bi YA; Kazolias DC; Davidson RE; Mireles RJ; Duignan DB; Choo EF; Zhao SX
    Drug Metab Dispos; 2007 Nov; 35(11):2111-8. PubMed ID: 17686907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier.
    Narang VS; Fraga C; Kumar N; Shen J; Throm S; Stewart CF; Waters CM
    Am J Physiol Cell Physiol; 2008 Aug; 295(2):C440-50. PubMed ID: 18524938
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
    Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
    Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver.
    Albermann N; Schmitz-Winnenthal FH; Z'graggen K; Volk C; Hoffmann MM; Haefeli WE; Weiss J
    Biochem Pharmacol; 2005 Sep; 70(6):949-58. PubMed ID: 16054595
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin.
    Vadlapatla RK; Vadlapudi AD; Kwatra D; Pal D; Mitra AK
    Int J Pharm; 2011 Nov; 420(1):26-33. PubMed ID: 21864659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gestational and pregnane X receptor-mediated regulation of placental ATP-binding cassette drug transporters in mice.
    Gahir SS; Piquette-Miller M
    Drug Metab Dispos; 2011 Mar; 39(3):465-71. PubMed ID: 21127142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Piperine enhances the bioavailability of silybin via inhibition of efflux transporters BCRP and MRP2.
    Bi X; Yuan Z; Qu B; Zhou H; Liu Z; Xie Y
    Phytomedicine; 2019 Feb; 54():98-108. PubMed ID: 30668388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine.
    Bruckmueller H; Martin P; Kähler M; Haenisch S; Ostrowski M; Drozdzik M; Siegmund W; Cascorbi I; Oswald S
    Mol Pharm; 2017 Jul; 14(7):2245-2253. PubMed ID: 28510455
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.