These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 34848455)

  • 21. Effects of the thioredoxin-1 inhibitor PX-12 on blood-brain barrier permeability in the early stage of focal cerebral ischemia.
    Chi OZ; Barsoum S; Grayson J; Liu X; Weiss HR
    Pharmacology; 2013; 92(3-4):175-81. PubMed ID: 24060905
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A Phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumors.
    Ramanathan RK; Kirkpatrick DL; Belani CP; Friedland D; Green SB; Chow HH; Cordova CA; Stratton SP; Sharlow ER; Baker A; Dragovich T
    Clin Cancer Res; 2007 Apr; 13(7):2109-14. PubMed ID: 17404093
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Upregulation of connexin43 contributes to PX-12-induced oxidative cell death.
    Li G; Gao K; Chi Y; Zhang X; Mitsui T; Yao J; Takeda M
    Tumour Biol; 2016 Jun; 37(6):7535-46. PubMed ID: 26684802
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synergistic interaction between thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide and sorafenib in liver cancer cells.
    Cao LP; Zhang C; Weng XY; Xie HY; Wu J; Zheng SS
    Hepatobiliary Pancreat Dis Int; 2020 Jun; 19(3):295-298. PubMed ID: 32247719
    [No Abstract]   [Full Text] [Related]  

  • 25. Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway.
    Zhang H; Jiang H; Zhang H; Liu J; Hu X; Chen L
    Eur J Pharmacol; 2019 Sep; 858():172477. PubMed ID: 31228450
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dysfunction of thioredoxin triggers inflammation through activation of autophagy in chicken cardiomyocytes.
    Yang J; Gong Y; Cai J; Liu Q; Zhang Y; Zheng Y; Yu D; Zhang Z
    Biofactors; 2020 Jul; 46(4):579-590. PubMed ID: 32031748
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Parallel syntheses of disulfide inhibitors of the thioredoxin redox system as potential antitumor agents.
    Kirkpatrick DL; Watson S; Kunkel M; Fletcher S; Ulhaq S; Powis G
    Anticancer Drug Des; 1999 Oct; 14(5):421-32. PubMed ID: 10766297
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Thioredoxin is implicated in the anti‑apoptotic effects of grape seed proanthocyanidin extract during hyperglycemia.
    Ren X; Lu H; Wang N; Zhang C; Ji Y; Cui S; Dong Y; Yang K; Du M; Diao F; Kong L
    Mol Med Rep; 2017 Nov; 16(5):7731-7737. PubMed ID: 28944891
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling.
    Cao Y; Yu L; Dai G; Zhang S; Zhang Z; Gao T; Guo W
    Eur J Pharmacol; 2017 Jan; 794():77-84. PubMed ID: 27845066
    [TBL] [Abstract][Full Text] [Related]  

  • 30. STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma.
    Oi T; Asanuma K; Matsumine A; Matsubara T; Nakamura T; Iino T; Asanuma Y; Goto M; Okuno K; Kakimoto T; Yada Y; Sudo A
    Int J Oncol; 2016 Dec; 49(6):2275-2284. PubMed ID: 27840900
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.
    Ory B; Baud'huin M; Verrecchia F; Royer BB; Quillard T; Amiaud J; Battaglia S; Heymann D; Redini F; Lamoureux F
    Clin Cancer Res; 2016 May; 22(10):2520-33. PubMed ID: 26712686
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Assessment of GSK1904529A as a promising anti-osteosarcoma agent.
    Fei HD; Yuan Q; Mao L; Chen FL; Cui ZH; Tao S; Ji F
    Oncotarget; 2017 Jul; 8(30):49646-49654. PubMed ID: 28572530
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Enhancement of metabolic oxidative stress-induced cytotoxicity by the thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide is mediated through the ASK1-SEK1-JNK1 pathway.
    Lee YJ; Kim JH; Chen J; Song JJ
    Mol Pharmacol; 2002 Dec; 62(6):1409-17. PubMed ID: 12435809
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Capsaicin inhibits proliferation and induces apoptosis in osteosarcoma cell lines via the mitogen‑activated protein kinase pathway.
    Zhang Y; Deng X; Lei T; Yu C; Wang Y; Zhao G; Luo X; Tang K; Quan Z; Jiang D
    Oncol Rep; 2017 Nov; 38(5):2685-2696. PubMed ID: 29048662
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways.
    Liao Z; Nan G; Yan Z; Zeng L; Deng Y; Ye J; Zhang Z; Qiao M; Li R; Denduluri S; Wang J; Wei Q; Geng N; Zhao L; Lu S; Wang X; Zhou G; Luu HH; Haydon RC; He TC; Wang Z
    Curr Cancer Drug Targets; 2015; 15(8):726-38. PubMed ID: 26118906
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Drug evaluation: the thioredoxin inhibitor PX-12 in the treatment of cancer.
    Galmarini CM
    Curr Opin Investig Drugs; 2006 Dec; 7(12):1108-15. PubMed ID: 17209529
    [TBL] [Abstract][Full Text] [Related]  

  • 38. AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments.
    Liao YX; Fu ZZ; Zhou CH; Shan LC; Wang ZY; Yin F; Zheng LP; Hua YQ; Cai ZD
    Oncol Rep; 2015 Jul; 34(1):33-42. PubMed ID: 25997540
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Glaucocalyxin A-induced oxidative stress inhibits the activation of STAT3 signaling pathway and suppresses osteosarcoma progression in vitro and in vivo.
    Mao M; Zhang T; Wang Z; Wang H; Xu J; Yin F; Wang G; Sun M; Wang Z; Hua Y; Cai Z
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1214-1225. PubMed ID: 30659925
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis.
    You BR; Shin HR; Park WH
    Int J Oncol; 2014 Jan; 44(1):301-8. PubMed ID: 24172913
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.