178 related articles for article (PubMed ID: 34850053)
1. Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation.
Lind KT; Chatwin HV; DeSisto J; Coleman P; Sanford B; Donson AM; Davies KD; Willard N; Ewing CA; Knox AJ; Mulcahy Levy JM; Gilani A; Green AL
J Neuropathol Exp Neurol; 2021 Dec; 80(12):1099-1107. PubMed ID: 34850053
[TBL] [Abstract][Full Text] [Related]
2. Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.
Roth JJ; Santi M; Pollock AN; Harding BN; Rorke-Adams LB; Tooke LS; Biegel JA
Brain Pathol; 2015 Mar; 25(2):182-92. PubMed ID: 25040262
[TBL] [Abstract][Full Text] [Related]
3. Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.
Forshew T; Tatevossian RG; Lawson AR; Ma J; Neale G; Ogunkolade BW; Jones TA; Aarum J; Dalton J; Bailey S; Chaplin T; Carter RL; Gajjar A; Broniscer A; Young BD; Ellison DW; Sheer D
J Pathol; 2009 Jun; 218(2):172-81. PubMed ID: 19373855
[TBL] [Abstract][Full Text] [Related]
4. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.
Cin H; Meyer C; Herr R; Janzarik WG; Lambert S; Jones DT; Jacob K; Benner A; Witt H; Remke M; Bender S; Falkenstein F; Van Anh TN; Olbrich H; von Deimling A; Pekrun A; Kulozik AE; Gnekow A; Scheurlen W; Witt O; Omran H; Jabado N; Collins VP; Brummer T; Marschalek R; Lichter P; Korshunov A; Pfister SM
Acta Neuropathol; 2011 Jun; 121(6):763-74. PubMed ID: 21424530
[TBL] [Abstract][Full Text] [Related]
5. Oncogenic KIAA1549-BRAF fusion with activation of the MAPK/ERK pathway in pediatric oligodendrogliomas.
Kumar A; Pathak P; Purkait S; Faruq M; Jha P; Mallick S; Suri V; Sharma MC; Suri A; Sarkar C
Cancer Genet; 2015 Mar; 208(3):91-5. PubMed ID: 25794445
[TBL] [Abstract][Full Text] [Related]
6. BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.
Lin A; Rodriguez FJ; Karajannis MA; Williams SC; Legault G; Zagzag D; Burger PC; Allen JC; Eberhart CG; Bar EE
J Neuropathol Exp Neurol; 2012 Jan; 71(1):66-72. PubMed ID: 22157620
[TBL] [Abstract][Full Text] [Related]
7. Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
Selt F; Hohloch J; Hielscher T; Sahm F; Capper D; Korshunov A; Usta D; Brabetz S; Ridinger J; Ecker J; Oehme I; Gronych J; Marquardt V; Pauck D; Bächli H; Stiles CD; von Deimling A; Remke M; Schuhmann MU; Pfister SM; Brummer T; Jones DT; Witt O; Milde T
Oncotarget; 2017 Feb; 8(7):11460-11479. PubMed ID: 28002790
[TBL] [Abstract][Full Text] [Related]
8. A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in
Usta D; Sigaud R; Buhl JL; Selt F; Marquardt V; Pauck D; Jansen J; Pusch S; Ecker J; Hielscher T; Vollmer J; Sommerkamp AC; Rubner T; Hargrave D; van Tilburg CM; Pfister SM; Jones DTW; Remke M; Brummer T; Witt O; Milde T
Mol Cancer Ther; 2020 Aug; 19(8):1736-1750. PubMed ID: 32451331
[TBL] [Abstract][Full Text] [Related]
9. LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.
van Tilburg CM; Kilburn LB; Perreault S; Schmidt R; Azizi AA; Cruz-Martínez O; Zápotocký M; Scheinemann K; Meeteren AYNS; Sehested A; Opocher E; Driever PH; Avula S; Ziegler DS; Capper D; Koch A; Sahm F; Qiu J; Tsao LP; Blackman SC; Manley P; Milde T; Witt R; Jones DTW; Hargrave D; Witt O
BMC Cancer; 2024 Jan; 24(1):147. PubMed ID: 38291372
[TBL] [Abstract][Full Text] [Related]
10. A novel GIT2-BRAF fusion in pilocytic astrocytoma.
Helgager J; Lidov HG; Mahadevan NR; Kieran MW; Ligon KL; Alexandrescu S
Diagn Pathol; 2017 Nov; 12(1):82. PubMed ID: 29141672
[TBL] [Abstract][Full Text] [Related]
11. Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
Tian Y; Rich BE; Vena N; Craig JM; Macconaill LE; Rajaram V; Goldman S; Taha H; Mahmoud M; Ozek M; Sav A; Longtine JA; Lindeman NI; Garraway LA; Ligon AH; Stiles CD; Santagata S; Chan JA; Kieran MW; Ligon KL
J Mol Diagn; 2011 Nov; 13(6):669-77. PubMed ID: 21884820
[TBL] [Abstract][Full Text] [Related]
12. CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles.
Jain P; Fierst TM; Han HJ; Smith TE; Vakil A; Storm PB; Resnick AC; Waanders AJ
Oncogene; 2017 Nov; 36(45):6348-6358. PubMed ID: 28806393
[TBL] [Abstract][Full Text] [Related]
13. A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.
Tomić TT; Olausson J; Wilzén A; Sabel M; Truvé K; Sjögren H; Dósa S; Tisell M; Lannering B; Enlund F; Martinsson T; Åman P; Abel F
PLoS One; 2017; 12(4):e0175638. PubMed ID: 28448514
[TBL] [Abstract][Full Text] [Related]
14. Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors.
Lee RP; Foster KA; Lillard JC; Klimo P; Ellison DW; Orr B; Boop FA
J Neurosurg Pediatr; 2017 Sep; 20(3):247-255. PubMed ID: 28686121
[TBL] [Abstract][Full Text] [Related]
15. BRAF alterations in pediatric low grade gliomas and mixed neuronal-glial tumors.
Dimitriadis E; Alexiou GA; Tsotsou P; Simeonidi E; Stefanaki K; Patereli A; Prodromou N; Pandis N
J Neurooncol; 2013 Jul; 113(3):353-8. PubMed ID: 23612919
[TBL] [Abstract][Full Text] [Related]
16. A new NFIA:RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma.
Yde CW; Sehested A; Mateu-Regué À; Østrup O; Scheie D; Nysom K; Nielsen FC; Rossing M
Cancer Genet; 2016 Oct; 209(10):440-444. PubMed ID: 27810072
[TBL] [Abstract][Full Text] [Related]
17. Detection and genomic analysis of BRAF fusions in Juvenile Pilocytic Astrocytoma through the combination and integration of multi-omic data.
Zwaig M; Baguette A; Hu B; Johnston M; Lakkis H; Nakada EM; Faury D; Juretic N; Ellezam B; Weil AG; Karamchandani J; Majewski J; Blanchette M; Taylor MD; Gallo M; Kleinman CL; Jabado N; Ragoussis J
BMC Cancer; 2022 Dec; 22(1):1297. PubMed ID: 36503484
[TBL] [Abstract][Full Text] [Related]
18. Molecular characterization of disseminated pilocytic astrocytomas.
Gessi M; Engels AC; Lambert S; Rothämel T; von Hornstein S; Collins VP; Denkhaus D; Gnekow A; Pietsch T
Neuropathol Appl Neurobiol; 2016 Apr; 42(3):273-8. PubMed ID: 26084390
[TBL] [Abstract][Full Text] [Related]
19. A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.
Sun Y; Alberta JA; Pilarz C; Calligaris D; Chadwick EJ; Ramkissoon SH; Ramkissoon LA; Garcia VM; Mazzola E; Goumnerova L; Kane M; Yao Z; Kieran MW; Ligon KL; Hahn WC; Garraway LA; Rosen N; Gray NS; Agar NY; Buhrlage SJ; Segal RA; Stiles CD
Neuro Oncol; 2017 Jun; 19(6):774-785. PubMed ID: 28082416
[TBL] [Abstract][Full Text] [Related]
20. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.
Tatevossian RG; Tang B; Dalton J; Forshew T; Lawson AR; Ma J; Neale G; Shurtleff SA; Bailey S; Gajjar A; Baker SJ; Sheer D; Ellison DW
Acta Neuropathol; 2010 Dec; 120(6):731-43. PubMed ID: 21046410
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
