161 related articles for article (PubMed ID: 34856909)
1. vHTS, 3-D Pharmacophore, QSAR and Molecular Docking Studies for the Identification of Phyto-derived ATP-Competitive Inhibitors of the BCR-ABL Kinase Domain.
Metibemu DS; Oyeneyin OE; Metibemu AO; Adeniran OY; Omotuyi IO
Curr Drug Discov Technol; 2022; 19(2):e021221198480. PubMed ID: 34856909
[TBL] [Abstract][Full Text] [Related]
2. Predictive models for designing potent tyrosine kinase inhibitors in chronic myeloid leukemia for understanding its molecular mechanism of resistance by molecular docking and dynamics simulations.
Melge AR; Kumar LG; K P; Nair SV; K M; C GM
J Biomol Struct Dyn; 2019 Nov; 37(18):4747-4766. PubMed ID: 30580670
[TBL] [Abstract][Full Text] [Related]
3. Development of a Predictive Pharmacophore Model and a 3D-QSAR Study for an in silico Screening of New Potent Bcr-Abl Kinase Inhibitors.
Vrontaki E; Melagraki G; Voskou S; Phylactides MS; Mavromoustakos T; Kleanthous M; Afantitis A
Mini Rev Med Chem; 2017; 17(3):188-204. PubMed ID: 28143387
[TBL] [Abstract][Full Text] [Related]
4. In-silico identification of inhibitors against mutated BCR-ABL protein of chronic myeloid leukemia: a virtual screening and molecular dynamics simulation study.
Kumar H; Raj U; Gupta S; Varadwaj PK
J Biomol Struct Dyn; 2016 Oct; 34(10):2171-83. PubMed ID: 26479578
[TBL] [Abstract][Full Text] [Related]
5. Discovery of Anticancer Hybrid Molecules by Supervised Machine Learning Models and
Melge AR; Parate S; Pavithran K; Koyakutty M; Mohan CG
J Chem Inf Model; 2022 Feb; 62(4):1126-1146. PubMed ID: 35172577
[TBL] [Abstract][Full Text] [Related]
6. Molecular Docking, G-QSAR Studies, Synthesis and Anticancer Screening of Some New 2-Phenazinamines as Bcr-Abl Tyrosine Kinase Inhibitors.
Kale MA; Sonwane GM
Curr Drug Discov Technol; 2020; 17(2):213-224. PubMed ID: 30210004
[TBL] [Abstract][Full Text] [Related]
7. Pharmacophore modeling of nilotinib as an inhibitor of ATP-binding cassette drug transporters and BCR-ABL kinase using a three-dimensional quantitative structure-activity relationship approach.
Shukla S; Kouanda A; Silverton L; Talele TT; Ambudkar SV
Mol Pharm; 2014 Jul; 11(7):2313-22. PubMed ID: 24865254
[TBL] [Abstract][Full Text] [Related]
8. Identification of novel tyrosine kinase inhibitors for drug resistant T315I mutant BCR-ABL: a virtual screening and molecular dynamics simulations study.
Banavath HN; Sharma OP; Kumar MS; Baskaran R
Sci Rep; 2014 Nov; 4():6948. PubMed ID: 25382104
[TBL] [Abstract][Full Text] [Related]
9. Identification of natural inhibitors of Bcr-Abl for the treatment of chronic myeloid leukemia.
Parcha P; Sarvagalla S; Madhuri B; Pajaniradje S; Baskaran V; Coumar MS; Rajasekaran B
Chem Biol Drug Des; 2017 Oct; 90(4):596-608. PubMed ID: 28338290
[TBL] [Abstract][Full Text] [Related]
10. Recent advances in Bcr-Abl tyrosine kinase inhibitors for overriding T315I mutation.
Liu J; Zhang Y; Huang H; Lei X; Tang G; Cao X; Peng J
Chem Biol Drug Des; 2021 Mar; 97(3):649-664. PubMed ID: 33034143
[TBL] [Abstract][Full Text] [Related]
11. The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities.
Ciftci HI; Ozturk SE; Ali TFS; Radwan MO; Tateishi H; Koga R; Ocak Z; Can M; Otsuka M; Fujita M
Biol Pharm Bull; 2018 Apr; 41(4):570-574. PubMed ID: 29386476
[TBL] [Abstract][Full Text] [Related]
12. Discovery and Protein Modeling Studies of Novel Compound Mutations Causing Resistance to Multiple Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia.
Iqbal Z; Absar M; Mahmood A; Aleem A; Iqbal M; Jameel A; Akhtar T; Karim S; Rasool M; Mirza Z; Khalid M; Akram AM; Sabar MF; Khalid AM; Aljarrah K; Iqbal J; Khalid M; Shah IH; Alanazi N
Asian Pac J Cancer Prev; 2020 Dec; 21(12):3517-3526. PubMed ID: 33369447
[TBL] [Abstract][Full Text] [Related]
13. Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression.
Akram AM; Iqbal Z; Akhtar T; Khalid AM; Sabar MF; Qazi MH; Aziz Z; Sajid N; Aleem A; Rasool M; Asif M; Aloraibi S; Aljamaan K; Iqbal M
Cancer Biol Ther; 2017 Apr; 18(4):214-221. PubMed ID: 28278078
[TBL] [Abstract][Full Text] [Related]
14. Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML).
Wu J; Wang A; Li X; Chen C; Qi Z; Hu C; Wang W; Wu H; Huang T; Zhao M; Wang W; Hu Z; Liu Q; Wang B; Wang L; Li L; Ge J; Ren T; Xia R; Liu J; Liu Q
Cancer Biol Ther; 2019; 20(6):877-885. PubMed ID: 30894066
[TBL] [Abstract][Full Text] [Related]
15. Three novel patient-derived BCR/ABL mutants show different sensitivity to second and third generation tyrosine kinase inhibitors.
Redaelli S; Mologni L; Rostagno R; Piazza R; Magistroni V; Ceccon M; Viltadi M; Flynn D; Gambacorti-Passerini C
Am J Hematol; 2012 Nov; 87(11):E125-8. PubMed ID: 23044928
[TBL] [Abstract][Full Text] [Related]
16. Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules.
Cao R; Wang Y; Huang N
J Chem Inf Model; 2015 Nov; 55(11):2435-42. PubMed ID: 26501568
[TBL] [Abstract][Full Text] [Related]
17. Structural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance.
Zhou T; Commodore L; Huang WS; Wang Y; Thomas M; Keats J; Xu Q; Rivera VM; Shakespeare WC; Clackson T; Dalgarno DC; Zhu X
Chem Biol Drug Des; 2011 Jan; 77(1):1-11. PubMed ID: 21118377
[TBL] [Abstract][Full Text] [Related]
18. Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107).
von Bubnoff N; Manley PW; Mestan J; Sanger J; Peschel C; Duyster J
Blood; 2006 Aug; 108(4):1328-33. PubMed ID: 16614241
[TBL] [Abstract][Full Text] [Related]
19. The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
O'Hare T; Zabriskie MS; Eide CA; Agarwal A; Adrian LT; You H; Corbin AS; Yang F; Press RD; Rivera VM; Toplin J; Wong S; Deininger MW; Druker BJ
Blood; 2011 Nov; 118(19):5250-4. PubMed ID: 21908430
[TBL] [Abstract][Full Text] [Related]
20. SHC004-221A1, a novel tyrosine kinase, potently inhibits T315I mutant BCR-ABL in chronic myeloid leukemia.
Wang D; Zheng Y; Li J; Wu H; Li X; Tang Y; Liu Y; Li J; Sun R; Zhou Y; Sun J; Yang Y
Eur J Pharmacol; 2017 Sep; 811():117-124. PubMed ID: 28595903
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
