191 related articles for article (PubMed ID: 34857889)
1. Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer.
Alhayyani S; McLeod L; West AC; Balic JJ; Hodges C; Yu L; Smith JA; Prodanovic Z; Bozinovski S; Kumar B; Ruwanpura SM; Saad MI; Jenkins BJ
Oncogene; 2022 Feb; 41(6):809-823. PubMed ID: 34857889
[TBL] [Abstract][Full Text] [Related]
2. STAT3-driven hematopoiesis and lymphopoiesis abnormalities are dependent on serine phosphorylation.
Balic JJ; White CL; Dawson R; Gough D; McCormack MP; Jenkins BJ
Cytokine; 2020 Mar; 130():155059. PubMed ID: 32200265
[TBL] [Abstract][Full Text] [Related]
3. Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity.
Balic JJ; Garama DJ; Saad MI; Yu L; West AC; West AJ; Livis T; Bhathal PS; Gough DJ; Jenkins BJ
Cancer Res; 2019 Oct; 79(20):5272-5287. PubMed ID: 31481496
[TBL] [Abstract][Full Text] [Related]
4. Blocking STAT3 by pyrvinium pamoate causes metabolic lethality in KRAS-mutant lung cancer.
Feng J; Jiang W; Liu Y; Huang W; Hu K; Li K; Chen J; Ma C; Sun Z; Pang X
Biochem Pharmacol; 2020 Jul; 177():113960. PubMed ID: 32298693
[TBL] [Abstract][Full Text] [Related]
5. ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Saad MI; Alhayyani S; McLeod L; Yu L; Alanazi M; Deswaerte V; Tang K; Jarde T; Smith JA; Prodanovic Z; Tate MD; Balic JJ; Watkins DN; Cain JE; Bozinovski S; Algar E; Kohmoto T; Ebi H; Ferlin W; Garbers C; Ruwanpura S; Sagi I; Rose-John S; Jenkins BJ
EMBO Mol Med; 2019 Apr; 11(4):. PubMed ID: 30833304
[TBL] [Abstract][Full Text] [Related]
6. STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates.
Huang G; Yan H; Ye S; Tong C; Ying QL
Stem Cells; 2014 May; 32(5):1149-60. PubMed ID: 24302476
[TBL] [Abstract][Full Text] [Related]
7. Phospho-Ser727 triggers a multistep inactivation of STAT3 by rapid dissociation of pY705-SH2 through C-terminal tail modulation.
Yang J; Kunimoto H; Katayama B; Zhao H; Shiromizu T; Wang L; Ozawa T; Tomonaga T; Tsuruta D; Nakajima K
Int Immunol; 2020 Feb; 32(2):73-88. PubMed ID: 31555812
[TBL] [Abstract][Full Text] [Related]
8. Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.
Miller A; McLeod L; Alhayyani S; Szczepny A; Watkins DN; Chen W; Enriori P; Ferlin W; Ruwanpura S; Jenkins BJ
Oncogene; 2017 May; 36(21):3059-3066. PubMed ID: 27893707
[TBL] [Abstract][Full Text] [Related]
9. Nuclear and cytosolic pS727-STAT3 levels correlate with overall survival of patients affected by clear cell renal cell carcinoma (ccRCC).
Arévalo J; Lorente D; Trilla E; Salcedo MT; Morote J; Meseguer A
Sci Rep; 2021 Mar; 11(1):6957. PubMed ID: 33772065
[TBL] [Abstract][Full Text] [Related]
10. Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
Thiem S; Eissmann MF; Elzer J; Jonas A; Putoczki TL; Poh A; Nguyen P; Preaudet A; Flanagan D; Vincan E; Waring P; Buchert M; Jarnicki A; Ernst M
Cancer Res; 2016 Apr; 76(8):2277-87. PubMed ID: 26837764
[TBL] [Abstract][Full Text] [Related]
11. STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.
Gough DJ; Marié IJ; Lobry C; Aifantis I; Levy DE
Blood; 2014 Oct; 124(14):2252-61. PubMed ID: 25150294
[TBL] [Abstract][Full Text] [Related]
12. Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer.
Tan X; Carretero J; Chen Z; Zhang J; Wang Y; Chen J; Li X; Ye H; Tang C; Cheng X; Hou N; Yang X; Wong KK
PLoS One; 2013; 8(11):e80885. PubMed ID: 24260500
[TBL] [Abstract][Full Text] [Related]
13. Constitutive STAT3 Serine Phosphorylation Promotes Helicobacter-Mediated Gastric Disease.
Balic JJ; Saad MI; Dawson R; West AJ; McLeod L; West AC; D'Costa K; Deswaerte V; Dev A; Sievert W; Gough DJ; Bhathal PS; Ferrero RL; Jenkins BJ
Am J Pathol; 2020 Jun; 190(6):1256-1270. PubMed ID: 32201262
[TBL] [Abstract][Full Text] [Related]
14. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Grabner B; Schramek D; Mueller KM; Moll HP; Svinka J; Hoffmann T; Bauer E; Blaas L; Hruschka N; Zboray K; Stiedl P; Nivarthi H; Bogner E; Gruber W; Mohr T; Zwick RH; Kenner L; Poli V; Aberger F; Stoiber D; Egger G; Esterbauer H; Zuber J; Moriggl R; Eferl R; Győrffy B; Penninger JM; Popper H; Casanova E
Nat Commun; 2015 Mar; 6():6285. PubMed ID: 25734337
[TBL] [Abstract][Full Text] [Related]
15. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.
Blaskovich MA; Sun J; Cantor A; Turkson J; Jove R; Sebti SM
Cancer Res; 2003 Mar; 63(6):1270-9. PubMed ID: 12649187
[TBL] [Abstract][Full Text] [Related]
16. Digitoxin promotes apoptosis and inhibits proliferation and migration by reducing HIF-1α and STAT3 in KRAS mutant human colon cancer cells.
Mi C; Cao X; Ma K; Wei M; Xu W; Lin Y; Zhang J; Wang TY
Chem Biol Interact; 2022 Jan; 351():109729. PubMed ID: 34717917
[TBL] [Abstract][Full Text] [Related]
17. Noncanonical pS727 post translational modification dictates major STAT3 activation and downstream functions in breast cancer.
Dimri S; Malhotra R; Shet T; Mokal S; Gupta S; De A
Exp Cell Res; 2020 Nov; 396(2):112313. PubMed ID: 33002501
[TBL] [Abstract][Full Text] [Related]
18. B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.
Frank DA; Mahajan S; Ritz J
J Clin Invest; 1997 Dec; 100(12):3140-8. PubMed ID: 9399961
[TBL] [Abstract][Full Text] [Related]
19. Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.
Gough DJ; Corlett A; Schlessinger K; Wegrzyn J; Larner AC; Levy DE
Science; 2009 Jun; 324(5935):1713-6. PubMed ID: 19556508
[TBL] [Abstract][Full Text] [Related]
20. Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.
Turkson J; Bowman T; Adnane J; Zhang Y; Djeu JY; Sekharam M; Frank DA; Holzman LB; Wu J; Sebti S; Jove R
Mol Cell Biol; 1999 Nov; 19(11):7519-28. PubMed ID: 10523640
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]