BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 34862354)

  • 1. Undifferentiated and Unresectable Sarcoma With NTRK3-Fusion in a Pediatric Patient Treated With Larotrectinib and Proton Beam Radiotherapy.
    Olsen MR; Denu RA; Lyon JB; Gulliver JM; Capitini CM; DeSantes KB
    J Pediatr Hematol Oncol; 2022 Apr; 44(3):e770-e774. PubMed ID: 34862354
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas.
    DuBois SG; Laetsch TW; Federman N; Turpin BK; Albert CM; Nagasubramanian R; Anderson ME; Davis JL; Qamoos HE; Reynolds ME; Cruickshank S; Cox MC; Hawkins DS; Mascarenhas L; Pappo AS
    Cancer; 2018 Nov; 124(21):4241-4247. PubMed ID: 30204247
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy.
    Lin R; Mallick AB; Wang ZX; Brown SA; Lu B; Jiang W
    Diagn Pathol; 2023 Oct; 18(1):116. PubMed ID: 37865792
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Larotrectinib followed by selitrectinib in a novel
    Goh XN; Seng MS; Loh AHP; Gupta A; Chang KTE; Iyer P
    J Oncol Pharm Pract; 2021 Mar; 27(2):485-489. PubMed ID: 32693686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adjuvant Maintenance Larotrectinib Therapy in 2 Children With NTRK Fusion-positive High-grade Cancers.
    Carter-Febres M; Schneller N; Fair D; Solomon D; Perry A; Roy A; Linscott L; Alashari M; Kestle JR; Bruggers CS
    J Pediatr Hematol Oncol; 2021 Oct; 43(7):e987-e990. PubMed ID: 33093355
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [A Case of Pediatric Soft Tissue Sarcoma with LMNA-NTRK1 Gene Fusion Treated with Larotrectinib under Single Patient Expanded Access System].
    Kato S; Fujimura J; Nozaki Y; Yamaguchi S; Takagi T; Hayashi T; Saito T; Henry D; Ku N; Suehara Y
    Gan To Kagaku Ryoho; 2019 Oct; 46(10):1595-1597. PubMed ID: 31631147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel TMTC2-NTRK3 fusion in undifferentiated high-grade pleomorphic sarcoma.
    Bai C; Zhang L; Wang Y; You X; Ju Y; Sun T; Fan Z
    J Cancer Res Clin Oncol; 2022 Oct; 148(10):2933-2937. PubMed ID: 35933643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.
    Bielack SS; Cox MC; Nathrath M; Apel K; Blattmann C; Holl T; Jenewein R; Klenk U; Klothaki P; Müller-Abt P; Ortega-Lawerenz S; Reynolds M; Scheer M; Simon-Klingenstein K; Stegmaier S; Tupper R; Vokuhl C; von Kalle T
    Ann Oncol; 2019 Nov; 30 Suppl 8():viii31-viii35. PubMed ID: 32223937
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinicopathological findings of pediatric NTRK fusion mesenchymal tumors.
    Kang J; Park JW; Won JK; Bae JM; Koh J; Yim J; Yun H; Kim SK; Choi JY; Kang HJ; Kim WS; Shin JH; Park SH
    Diagn Pathol; 2020 Sep; 15(1):114. PubMed ID: 32957984
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A newborn with a large NTRK fusion positive infantile fibrosarcoma successfully treated with larotrectinib.
    Caldwell KJ; De La Cuesta E; Morin C; Pappo A; Helmig S
    Pediatr Blood Cancer; 2020 Sep; 67(9):e28330. PubMed ID: 32452122
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Larotrectinib, a selective tropomyosin receptor kinase inhibitor for adult and pediatric tropomyosin receptor kinase fusion cancers.
    Farago AF; Demetri GD
    Future Oncol; 2020 Mar; 16(9):417-425. PubMed ID: 32129093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic strategies and clinical evolution of patients with infantile fibrosarcoma: a unique paediatric case series.
    Corral Sánchez MD; Jiménez Carrascoso R; Rubio Aparicio P; Plaza López de Sabando D; Sastre Urgelles A; Pozo-Kreilinger JJ; López Gutiérrez JC; Gómez Cervantes M; Ortiz Cruz EJ; Pérez-Martínez A
    Clin Transl Oncol; 2023 Nov; 25(11):3307-3311. PubMed ID: 37097530
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101.
    Doebele RC; Davis LE; Vaishnavi A; Le AT; Estrada-Bernal A; Keysar S; Jimeno A; Varella-Garcia M; Aisner DL; Li Y; Stephens PJ; Morosini D; Tuch BB; Fernandes M; Nanda N; Low JA
    Cancer Discov; 2015 Oct; 5(10):1049-57. PubMed ID: 26216294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Diagnostic testing approaches for the identification of patients with TRK fusion cancer prior to enrollment in clinical trials investigating larotrectinib.
    Rudzinski ER; Hechtman J; Roy-Chowdhuri S; Rudolph M; Lockwood CM; Silvertown J; Wierzbinska J; Shen K; Norenberg R; Nogai H; Hong DS; Drilon A; Laetsch TW
    Cancer Genet; 2022 Jan; 260-261():46-52. PubMed ID: 34929613
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improving outcomes in pediatric NTRK gene fusion-positive solid tumors: importance of genomic testing and targeted therapy with the TRK inhibitor larotrectinib.
    Laetsch TW
    Clin Adv Hematol Oncol; 2024 May; 22 Suppl 3(4):1-11. PubMed ID: 38739704
    [No Abstract]   [Full Text] [Related]  

  • 16. Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.
    Bielack SS; Cox MC; Nathrath M; Apel K; Blattmann C; Holl T; Jenewein R; Klenk U; Klothaki P; Müller-Abt P; Ortega-Lawerenz S; Reynolds M; Scheer M; Simon-Klingenstein K; Stegmaier S; Tupper R; Vokuhl C; von Kalle T
    Ann Oncol; 2019 Nov; 30(Suppl_8):viii31-viii35. PubMed ID: 31738425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mixed response and mechanisms of resistance to larotrectinib in metastatic carcinoma ex pleomorphic adenoma of the parotid harboring an NTRK2 fusion: A case report.
    Pircher M; Briner HR; Bonomo M; Horcic M; Petrausch U; Helbling D; Winder T
    Medicine (Baltimore); 2021 Jan; 100(4):e24463. PubMed ID: 33530256
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The potential long-term comparative effectiveness of larotrectinib vs standard of care for treatment of metastatic TRK fusion thyroid cancer, colorectal cancer, and soft tissue sarcoma.
    Suh K; Carlson JJ; Xia F; Williamson T; Sullivan SD
    J Manag Care Spec Pharm; 2022 Jun; 28(6):622-630. PubMed ID: 35362337
    [No Abstract]   [Full Text] [Related]  

  • 19. Myxoid spindle cell sarcoma with ETV6-NTRK3 fusion.
    Kyriazoglou A; Dimitriadis E; Mahaira L; Kotsantis J; Kouloulias V; Kontogeorgakos V; Psyrri A; Agrogiannis G
    Cancer Genet; 2022 Nov; 268-269():93-96. PubMed ID: 36274330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluating larotrectinib for the treatment of advanced solid tumors harboring an NTRK gene fusion.
    Filippi R; Depetris I; Satolli MA
    Expert Opin Pharmacother; 2021 Apr; 22(6):677-684. PubMed ID: 33576301
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.