BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 34865993)

  • 1. VX765 alleviates dextran sulfate sodium-induced colitis in mice by suppressing caspase-1-mediated pyroptosis.
    Wang L; Dong X; Feng S; Pan H; Jang X; Chen L; Zhao Y; Chen W; Huang Z
    Int Immunopharmacol; 2022 Jan; 102():108405. PubMed ID: 34865993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. VX765 Attenuates Pyroptosis and HMGB1/TLR4/NF-
    Sun Z; Nyanzu M; Yang S; Zhu X; Wang K; Ru J; Yu E; Zhang H; Wang Z; Shen J; Zhuge Q; Huang L
    Oxid Med Cell Longev; 2020; 2020():7879629. PubMed ID: 32377306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Caspase-1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia.
    Li J; Hao JH; Yao D; Li R; Li XF; Yu ZY; Luo X; Liu XH; Wang MH; Wang W
    CNS Neurosci Ther; 2020 Sep; 26(9):925-939. PubMed ID: 32343048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction.
    Wu S; Li Z; Ye M; Liu C; Liu H; He X; Qin Y; Liang F; Pan L; Lin F
    Biomed Res Int; 2021; 2021():4525988. PubMed ID: 34977239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury.
    Chen J; Chen YQ; Wang SN; Duan FX; Shi YJ; Ding SQ; Hu JG; Lü HZ
    Mol Med Rep; 2020 Jul; 22(1):33-42. PubMed ID: 32377730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cannabinoid 1 Receptor Antagonists Play a Neuroprotective Role in Chronic Alcoholic Hippocampal Injury Related to Pyroptosis Pathway.
    Zhang D; Liu X; Dong X; Zhu R; Jiang J; Ye Y; Jiang Y
    Alcohol Clin Exp Res; 2020 Aug; 44(8):1585-1597. PubMed ID: 32524615
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis.
    Xu XE; Liu L; Wang YC; Wang CT; Zheng Q; Liu QX; Li ZF; Bai XJ; Liu XH
    Brain Behav Immun; 2019 Aug; 80():859-870. PubMed ID: 31145977
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
    Liu D; Dong Z; Xiang F; Liu H; Wang Y; Wang Q; Rao J
    Neurochem Res; 2020 Feb; 45(2):437-454. PubMed ID: 31865520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats.
    Zhang Z; Bai H; Ma X; Shen M; Li R; Qiu D; Li S; Gao L
    J Neuroinflammation; 2021 Oct; 18(1):239. PubMed ID: 34666787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis.
    Zhang D; Ge F; Ji J; Li YJ; Zhang FR; Wang SY; Zhang SJ; Zhang DM; Chen M
    Front Pharmacol; 2023; 14():1218477. PubMed ID: 37954856
    [No Abstract]   [Full Text] [Related]  

  • 11. Inhibition of GSDMD-mediated pyroptosis triggered by Trichinella spiralis intervention contributes to the alleviation of DSS-induced ulcerative colitis in mice.
    Ma ZR; Li ZL; Zhang N; Lu B; Li XW; Huang YH; Nouhoum D; Liu XS; Xiao KC; Cai LT; Xu SR; Yang XO; Huang SQ; Wu X
    Parasit Vectors; 2023 Aug; 16(1):280. PubMed ID: 37580819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects and mechanisms of potent caspase-1 inhibitor VX765 treatment on collagen-induced arthritis in mice.
    Zhang Y; Zheng Y
    Clin Exp Rheumatol; 2016; 34(1):111-8. PubMed ID: 26742834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of the caspase-1/GSDMD-mediated pyroptotic signaling pathway through dexamethasone alleviates corneal alkali injuries.
    Tan Y; Zhang M; Pan Y; Feng H; Xie L
    Exp Eye Res; 2022 Jan; 214():108858. PubMed ID: 34822855
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Necrosulfonamide ameliorates intestinal inflammation via inhibiting GSDMD-medicated pyroptosis and MLKL-mediated necroptosis.
    Yang W; Tao K; Wang Y; Huang Y; Duan C; Wang T; Li C; Zhang P; Yin Y; Gao J; Li R
    Biochem Pharmacol; 2022 Dec; 206():115338. PubMed ID: 36347275
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kuijieling decoction suppresses NLRP3-Mediated pyroptosis to alleviate inflammation and experimental colitis in vivo and in vitro.
    Jie F; Xiao S; Qiao Y; You Y; Feng Y; Long Y; Li S; Wu Y; Li Y; Du Q
    J Ethnopharmacol; 2021 Jan; 264():113243. PubMed ID: 32781258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
    Bauer C; Duewell P; Mayer C; Lehr HA; Fitzgerald KA; Dauer M; Tschopp J; Endres S; Latz E; Schnurr M
    Gut; 2010 Sep; 59(9):1192-9. PubMed ID: 20442201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis.
    McKenzie BA; Mamik MK; Saito LB; Boghozian R; Monaco MC; Major EO; Lu JQ; Branton WG; Power C
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):E6065-E6074. PubMed ID: 29895691
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Canna x generalis L.H. Bailey rhizome extract ameliorates dextran sulfate sodium-induced colitis via modulating intestinal mucosal dysfunction, oxidative stress, inflammation, and TLR4/ NF-ҡB and NLRP3 inflammasome pathways.
    Mahmoud TN; El-Maadawy WH; Kandil ZA; Khalil H; El-Fiky NM; El Alfy TSMA
    J Ethnopharmacol; 2021 Apr; 269():113670. PubMed ID: 33301917
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production.
    Gong Z; Zhao S; Zhou J; Yan J; Wang L; Du X; Li H; Chen Y; Cai W; Wu J
    Mol Immunol; 2018 Dec; 104():11-19. PubMed ID: 30396035
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation.
    Guo W; Liu W; Jin B; Geng J; Li J; Ding H; Wu X; Xu Q; Sun Y; Gao J
    Int Immunopharmacol; 2015 Feb; 24(2):232-238. PubMed ID: 25523461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.