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4. SARM1 is a metabolic sensor activated by an increased NMN/NAD Figley MD; Gu W; Nanson JD; Shi Y; Sasaki Y; Cunnea K; Malde AK; Jia X; Luo Z; Saikot FK; Mosaiab T; Masic V; Holt S; Hartley-Tassell L; McGuinness HY; Manik MK; Bosanac T; Landsberg MJ; Kerry PS; Mobli M; Hughes RO; Milbrandt J; Kobe B; DiAntonio A; Ve T Neuron; 2021 Apr; 109(7):1118-1136.e11. PubMed ID: 33657413 [TBL] [Abstract][Full Text] [Related]
5. SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons. Miyamoto T; Kim C; Chow J; Dugas JC; DeGroot J; Bagdasarian AL; Thottumkara AP; Larhammar M; Calvert ME; Fox BM; Lewcock JW; Kane LA J Biol Chem; 2024 Feb; 300(2):105630. PubMed ID: 38199568 [TBL] [Abstract][Full Text] [Related]
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7. Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons. Hinz FI; Villegas CLM; Roberts JT; Yao H; Gaddam S; Delwig A; Green SA; Fredrickson C; Adrian M; Asuncion RR; Cheung TK; Hayne M; Hackos DH; Rose CM; Richmond D; Hoogenraad CC J Neurosci; 2024 Jun; 44(24):. PubMed ID: 38692735 [TBL] [Abstract][Full Text] [Related]
8. Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. Sasaki Y; Zhu J; Shi Y; Gu W; Kobe B; Ve T; DiAntonio A; Milbrandt J Exp Neurol; 2021 Nov; 345():113842. PubMed ID: 34403688 [TBL] [Abstract][Full Text] [Related]
9. cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons. Sasaki Y; Engber TM; Hughes RO; Figley MD; Wu T; Bosanac T; Devraj R; Milbrandt J; Krauss R; DiAntonio A Exp Neurol; 2020 Jul; 329():113252. PubMed ID: 32087251 [TBL] [Abstract][Full Text] [Related]
10. NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD Sasaki Y; Nakagawa T; Mao X; DiAntonio A; Milbrandt J Elife; 2016 Oct; 5():. PubMed ID: 27735788 [TBL] [Abstract][Full Text] [Related]
11. Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease. Peters OM; Weiss A; Metterville J; Song L; Logan R; Smith GA; Schwarzschild MA; Mueller C; Brown RH; Freeman M Neurobiol Dis; 2021 Jul; 155():105368. PubMed ID: 33892050 [TBL] [Abstract][Full Text] [Related]
12. SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation. Summers DW; Gibson DA; DiAntonio A; Milbrandt J Proc Natl Acad Sci U S A; 2016 Oct; 113(41):E6271-E6280. PubMed ID: 27671644 [TBL] [Abstract][Full Text] [Related]
13. Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program. Geisler S; Doan RA; Cheng GC; Cetinkaya-Fisgin A; Huang SX; Höke A; Milbrandt J; DiAntonio A JCI Insight; 2019 Sep; 4(17):. PubMed ID: 31484833 [TBL] [Abstract][Full Text] [Related]
14. SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration. Ko KW; Milbrandt J; DiAntonio A J Cell Biol; 2020 Aug; 219(8):. PubMed ID: 32609299 [TBL] [Abstract][Full Text] [Related]