BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 34870751)

  • 1. Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.
    Artunc F; Bohnert BN; Schneider JC; Staudner T; Sure F; Ilyaskin AV; Wörn M; Essigke D; Janessa A; Nielsen NV; Birkenfeld AL; Etscheid M; Haerteis S; Korbmacher C; Kanse SM
    Pflugers Arch; 2022 Feb; 474(2):217-229. PubMed ID: 34870751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasma kallikrein activates the epithelial sodium channel in vitro but is not essential for volume retention in nephrotic mice.
    Haerteis S; Schork A; Dörffel T; Bohnert BN; Nacken R; Wörn M; Xiao M; Essigke D; Janessa A; Schmaier AH; Feener EP; Häring HU; Bertog M; Korbmacher C; Artunc F
    Acta Physiol (Oxf); 2018 Sep; 224(1):e13060. PubMed ID: 29489063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome.
    Bohnert BN; Menacher M; Janessa A; Wörn M; Schork A; Daiminger S; Kalbacher H; Häring HU; Daniel C; Amann K; Sure F; Bertog M; Haerteis S; Korbmacher C; Artunc F
    Kidney Int; 2018 Jan; 93(1):159-172. PubMed ID: 29042083
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity.
    Essigke D; Bohnert BN; Janessa A; Wörn M; Omage K; Kalbacher H; Birkenfeld AL; Bugge TH; Szabo R; Artunc F
    Pflugers Arch; 2022 Jun; 474(6):613-624. PubMed ID: 35312839
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Experimental nephrotic syndrome leads to proteolytic activation of the epithelial Na
    Bohnert BN; Essigke D; Janessa A; Schneider JC; Wörn M; Kalo MZ; Xiao M; Kong L; Omage K; Hennenlotter J; Amend B; Birkenfeld AL; Artunc F
    Am J Physiol Renal Physiol; 2021 Oct; 321(4):F480-F493. PubMed ID: 34423678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome.
    Bohnert BN; Daiminger S; Wörn M; Sure F; Staudner T; Ilyaskin AV; Batbouta F; Janessa A; Schneider JC; Essigke D; Kanse S; Haerteis S; Korbmacher C; Artunc F
    Acta Physiol (Oxf); 2019 Dec; 227(4):e13286. PubMed ID: 31006168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites.
    Haerteis S; Krappitz A; Krappitz M; Murphy JE; Bertog M; Krueger B; Nacken R; Chung H; Hollenberg MD; Knecht W; Bunnett NW; Korbmacher C
    J Biol Chem; 2014 Jul; 289(27):19067-78. PubMed ID: 24841206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.
    Sure F; Bertog M; Afonso S; Diakov A; Rinke R; Madej MG; Wittmann S; Gramberg T; Korbmacher C; Ilyaskin AV
    J Biol Chem; 2022 Jun; 298(6):102004. PubMed ID: 35504352
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Plasmin in nephrotic urine activates the epithelial sodium channel.
    Svenningsen P; Bistrup C; Friis UG; Bertog M; Haerteis S; Krueger B; Stubbe J; Jensen ON; Thiesson HC; Uhrenholt TR; Jespersen B; Jensen BL; Korbmacher C; Skøtt O
    J Am Soc Nephrol; 2009 Feb; 20(2):299-310. PubMed ID: 19073825
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S.
    Haerteis S; Krappitz M; Bertog M; Krappitz A; Baraznenok V; Henderson I; Lindström E; Murphy JE; Bunnett NW; Korbmacher C
    Pflugers Arch; 2012 Oct; 464(4):353-65. PubMed ID: 22864553
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proteolytic Activity against the Distal Polybasic Tract of the Gamma Subunit of the Epithelial Sodium Channel ENaC in Nephrotic Urine.
    Wörn M; Kalbacher H; Artunc F
    Curr Med Chem; 2022; 29(42):6433-6445. PubMed ID: 35676854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proteasuria-The impact of active urinary proteases on sodium retention in nephrotic syndrome.
    Artunc F; Wörn M; Schork A; Bohnert BN
    Acta Physiol (Oxf); 2019 Apr; 225(4):e13249. PubMed ID: 30597733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Physiological regulation of epithelial sodium channel by proteolysis.
    Svenningsen P; Friis UG; Bistrup C; Buhl KB; Jensen BL; Skøtt O
    Curr Opin Nephrol Hypertens; 2011 Sep; 20(5):529-33. PubMed ID: 21670672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel.
    Haerteis S; Krappitz M; Diakov A; Krappitz A; Rauh R; Korbmacher C
    J Gen Physiol; 2012 Oct; 140(4):375-89. PubMed ID: 22966015
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of sodium transport by ENaC in the kidney.
    Hamm LL; Feng Z; Hering-Smith KS
    Curr Opin Nephrol Hypertens; 2010 Jan; 19(1):98-105. PubMed ID: 19996890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.
    Diakov A; Bera K; Mokrushina M; Krueger B; Korbmacher C
    J Physiol; 2008 Oct; 586(19):4587-608. PubMed ID: 18669538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Energetic and structural basis for activation of the epithelial sodium channel by matriptase.
    Kota P; García-Caballero A; Dang H; Gentzsch M; Stutts MJ; Dokholyan NV
    Biochemistry; 2012 Apr; 51(16):3460-9. PubMed ID: 22471557
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice.
    Essigke D; Ilyaskin AV; Wörn M; Bohnert BN; Xiao M; Daniel C; Amann K; Birkenfeld AL; Szabo R; Bugge TH; Korbmacher C; Artunc F
    Acta Physiol (Oxf); 2021 May; 232(1):e13640. PubMed ID: 33650216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome.
    Larionov A; Dahlke E; Kunke M; Zanon Rodriguez L; Schiessl IM; Magnin JL; Kern U; Alli AA; Mollet G; Schilling O; Castrop H; Theilig F
    J Cell Mol Med; 2019 Oct; 23(10):6543-6553. PubMed ID: 31368174
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Incorporation of the δ-subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in
    Wichmann L; Vowinkel KS; Perniss A; Manzini I; Althaus M
    J Biol Chem; 2018 May; 293(18):6647-6658. PubMed ID: 29576549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.