These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 34870892)

  • 1. Prodrugs of E-selectin Antagonists with Enhanced Pharmacokinetic Properties.
    Dätwyler P; Jiang X; Wagner B; Varga N; Mühlethaler T; Hostettler K; Rabbani S; Schwardt O; Ernst B
    ChemMedChem; 2022 Jan; 17(1):e202100634. PubMed ID: 34870892
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol.
    Azzolini M; Mattarei A; La Spina M; Marotta E; Zoratti M; Paradisi C; Biasutto L
    Mol Pharm; 2015 Sep; 12(9):3441-54. PubMed ID: 26252229
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
    Prueksaritanont T; Gorham LM; Breslin MJ; Hutchinson JH; Hartman GD; Vyas KP; Baillie TA
    Drug Metab Dispos; 1997 Aug; 25(8):978-84. PubMed ID: 9280406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative chemical and biological hydrolytic stability of homologous esters and isosteres.
    de Souza HMR; Guedes JS; Freitas RHCN; Gelves LGV; Fokoue HH; Sant'Anna CMR; Barreiro EJ; Lima LM
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):718-727. PubMed ID: 35156494
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemical synthesis of an indomethacin ester prodrug and its metabolic activation by human carboxylesterase 1.
    Takahashi M; Ogawa T; Kashiwagi H; Fukushima F; Yoshitsugu M; Haba M; Hosokawa M
    Bioorg Med Chem Lett; 2018 Apr; 28(6):997-1000. PubMed ID: 29503023
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetic studies of naproxen amides of some amino acid esters with promising colorectal cancer chemopreventive activity.
    Aboul-Fadl T; Al-Hamad SS; Fouad EA
    Bioorg Chem; 2018 Feb; 76():370-379. PubMed ID: 29241109
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intestinal absorption and activation of decitabine amino acid ester prodrugs mediated by peptide transporter PEPT1 and enterocyte enzymes.
    Tao W; Zhao D; Sun M; Wang Z; Lin B; Bao Y; Li Y; He Z; Sun Y; Sun J
    Int J Pharm; 2018 Apr; 541(1-2):64-71. PubMed ID: 29471144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Evaluation of the Oral Absorption of Ester-type Prodrugs].
    Ohura K
    Yakugaku Zasshi; 2020; 140(3):369-376. PubMed ID: 32115554
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of amino acid ester prodrugs of acyclovir after oral administration: interaction with the transporters on Caco-2 cells.
    Katragadda S; Jain R; Kwatra D; Hariharan S; Mitra AK
    Int J Pharm; 2008 Oct; 362(1-2):93-101. PubMed ID: 18638532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery.
    Puris E; Gynther M; Huttunen J; Auriola S; Huttunen KM
    Eur J Pharm Sci; 2019 Mar; 129():99-109. PubMed ID: 30625368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.
    Gupta D; Varghese Gupta S; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
    Mol Pharm; 2013 Feb; 10(2):512-22. PubMed ID: 23244438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of an oral prodrug alalevonadifloxacin for the treatment of MRSA infection.
    Bhawsar S; Kale R; Deshpande P; Yeole R; Bhagwat S; Patel M
    Bioorg Med Chem Lett; 2021 Dec; 54():128432. PubMed ID: 34757217
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbonate esters turn camptothecin-unsaturated fatty acid prodrugs into nanomedicines for cancer therapy.
    Li Y; Kang T; Wu Y; Chen Y; Zhu J; Gou M
    Chem Commun (Camb); 2018 Feb; 54(16):1996-1999. PubMed ID: 29411840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New natural amino acid-bearing prodrugs boost pterostilbene's oral pharmacokinetic and distribution profile.
    Azzolini M; Mattarei A; La Spina M; Fanin M; Chiodarelli G; Romio M; Zoratti M; Paradisi C; Biasutto L
    Eur J Pharm Biopharm; 2017 Jun; 115():149-158. PubMed ID: 28254379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies.
    Abdel-Azeem AZ; Abdel-Hafez AA; El-Karamany GS; Farag HH
    Bioorg Med Chem; 2009 May; 17(10):3665-70. PubMed ID: 19398345
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis.
    Dawadi S; Kawamura S; Rubenstein A; Remmel R; Aldrich CC
    Bioorg Med Chem; 2016 Mar; 24(6):1314-21. PubMed ID: 26875934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preparation, properties, reactions, and adenosine receptor affinities of sulfophenylxanthine nitrophenyl esters: toward the development of sulfonic acid prodrugs with peroral bioavailability.
    Yan L; Müller CE
    J Med Chem; 2004 Feb; 47(4):1031-43. PubMed ID: 14761205
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).
    Parang K; Wiebe LI; Knaus EE
    Curr Med Chem; 2000 Oct; 7(10):995-1039. PubMed ID: 10911016
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.
    Han H; de Vrueh RL; Rhie JK; Covitz KM; Smith PL; Lee CP; Oh DM; Sadée W; Amidon GL
    Pharm Res; 1998 Aug; 15(8):1154-9. PubMed ID: 9706043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
    Schumacher-Klinger A; Fanous J; Merzbach S; Weinmüller M; Reichart F; Räder AFB; Gitlin-Domagalska A; Gilon C; Kessler H; Hoffman A
    Mol Pharm; 2018 Aug; 15(8):3468-3477. PubMed ID: 29976060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.