These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 34876589)

  • 1. eIF2B-capturing viral protein NSs suppresses the integrated stress response.
    Kashiwagi K; Shichino Y; Osaki T; Sakamoto A; Nishimoto M; Takahashi M; Mito M; Weber F; Ikeuchi Y; Iwasaki S; Ito T
    Nat Commun; 2021 Dec; 12(1):7102. PubMed ID: 34876589
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B.
    Schoof M; Wang L; Cogan JZ; Lawrence RE; Boone M; Wuerth JD; Frost A; Walter P
    Nat Commun; 2021 Dec; 12(1):7103. PubMed ID: 34876554
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response.
    Ito T; Wuerth JD; Weber F
    J Biol Chem; 2023 Nov; 299(11):105287. PubMed ID: 37742919
    [TBL] [Abstract][Full Text] [Related]  

  • 4. eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition.
    Wuerth JD; Habjan M; Kainulainen M; Berisha B; Bertheloot D; Superti-Furga G; Pichlmair A; Weber F
    mBio; 2020 Jul; 11(4):. PubMed ID: 32665273
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
    Zyryanova AF; Kashiwagi K; Rato C; Harding HP; Crespillo-Casado A; Perera LA; Sakamoto A; Nishimoto M; Yonemochi M; Shirouzu M; Ito T; Ron D
    Mol Cell; 2021 Jan; 81(1):88-103.e6. PubMed ID: 33220178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. eIF2B and the Integrated Stress Response: A Structural and Mechanistic View.
    Marintchev A; Ito T
    Biochemistry; 2020 Apr; 59(13):1299-1308. PubMed ID: 32200625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for eIF2B inhibition in integrated stress response.
    Kashiwagi K; Yokoyama T; Nishimoto M; Takahashi M; Sakamoto A; Yonemochi M; Shirouzu M; Ito T
    Science; 2019 May; 364(6439):495-499. PubMed ID: 31048492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K; Qiu H; Dong J; Zhang F; Barthlme D; Hinnebusch AG
    Mol Cell Biol; 2010 Nov; 30(21):5218-33. PubMed ID: 20805354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eiF2b.
    Kimball SR; Fabian JR; Pavitt GD; Hinnebusch AG; Jefferson LS
    J Biol Chem; 1998 May; 273(21):12841-5. PubMed ID: 9582312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.
    Bogorad AM; Lin KY; Marintchev A
    Nucleic Acids Res; 2017 Nov; 45(20):11962-11979. PubMed ID: 29036434
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
    Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.
    Pavitt GD; Ramaiah KV; Kimball SR; Hinnebusch AG
    Genes Dev; 1998 Feb; 12(4):514-26. PubMed ID: 9472020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association.
    Rabouw HH; Visser LJ; Passchier TC; Langereis MA; Liu F; Giansanti P; van Vliet ALW; Dekker JG; van der Grein SG; Saucedo JG; Anand AA; Trellet ME; Bonvin AMJJ; Walter P; Heck AJR; de Groot RJ; van Kuppeveld FJM
    Nat Microbiol; 2020 Nov; 5(11):1361-1373. PubMed ID: 32690955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View.
    Bogorad AM; Lin KY; Marintchev A
    Biochemistry; 2018 Mar; 57(9):1426-1435. PubMed ID: 29425030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2.
    Yang W; Hinnebusch AG
    Mol Cell Biol; 1996 Nov; 16(11):6603-16. PubMed ID: 8887689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. eIF2B conformation and assembly state regulate the integrated stress response.
    Schoof M; Boone M; Wang L; Lawrence R; Frost A; Walter P
    Elife; 2021 Mar; 10():. PubMed ID: 33688831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The structural basis of translational control by eIF2 phosphorylation.
    Adomavicius T; Guaita M; Zhou Y; Jennings MD; Latif Z; Roseman AM; Pavitt GD
    Nat Commun; 2019 May; 10(1):2136. PubMed ID: 31086188
    [TBL] [Abstract][Full Text] [Related]  

  • 18. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
    Kenner LR; Anand AA; Nguyen HC; Myasnikov AG; Klose CJ; McGeever LA; Tsai JC; Miller-Vedam LE; Walter P; Frost A
    Science; 2019 May; 364(6439):491-495. PubMed ID: 31048491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A C-term truncated EIF2Bγ protein encoded by an intronically polyadenylated isoform introduces unfavorable EIF2Bγ-EIF2γ interactions.
    Circir A; Koksal Bicakci G; Savas B; Doken DN; Henden ŞO; Can T; Karaca E; Erson-Bensan AE
    Proteins; 2022 Mar; 90(3):889-897. PubMed ID: 34796993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of eIF2B and insights into eIF2-eIF2B interactions.
    Kashiwagi K; Ito T; Yokoyama S
    FEBS J; 2017 Mar; 284(6):868-874. PubMed ID: 27627185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.