181 related articles for article (PubMed ID: 34886684)
1. Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis.
Awan S; Lambert M; Imtiaz A; Alpy F; Tomasetto C; Oulad-Abdelghani M; Schaeffer C; Moritz C; Julien-David D; Najib S; Martinez LO; Matz RL; Collet X; Silva-Rojas R; Böhm J; Herz J; Terrand J; Boucher P
Circ Res; 2022 Jan; 130(2):184-199. PubMed ID: 34886684
[TBL] [Abstract][Full Text] [Related]
2. ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C.
Lim CY; Davis OB; Shin HR; Zhang J; Berdan CA; Jiang X; Counihan JL; Ory DS; Nomura DK; Zoncu R
Nat Cell Biol; 2019 Oct; 21(10):1206-1218. PubMed ID: 31548609
[TBL] [Abstract][Full Text] [Related]
3. Wnt5a/Ror2 pathway contributes to the regulation of cholesterol homeostasis and inflammatory response in atherosclerosis.
Zhang CJ; Zhu N; Liu Z; Shi Z; Long J; Zu XY; Tang ZW; Hu ZY; Liao DF; Qin L
Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Feb; 1865(2):158547. PubMed ID: 31678514
[TBL] [Abstract][Full Text] [Related]
4. Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.
Goldman SD; Krise JP
J Biol Chem; 2010 Feb; 285(7):4983-94. PubMed ID: 20007703
[TBL] [Abstract][Full Text] [Related]
5. NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C.
Davis OB; Shin HR; Lim CY; Wu EY; Kukurugya M; Maher CF; Perera RM; Ordonez MP; Zoncu R
Dev Cell; 2021 Feb; 56(3):260-276.e7. PubMed ID: 33308480
[TBL] [Abstract][Full Text] [Related]
6. NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes.
Kutchukian C; Vivas O; Casas M; Jones JG; Tiscione SA; Simó S; Ory DS; Dixon RE; Dickson EJ
EMBO J; 2021 Jul; 40(13):e105990. PubMed ID: 34019311
[TBL] [Abstract][Full Text] [Related]
7. Molecular dynamics study with mutation shows that N-terminal domain structural re-orientation in Niemann-Pick type C1 is required for proper alignment of cholesterol transport.
Yoon HJ; Jeong H; Lee HH; Jang S
J Neurochem; 2021 Mar; 156(6):967-978. PubMed ID: 32880929
[TBL] [Abstract][Full Text] [Related]
8. Rab7a-mTORC1 signaling-mediated cholesterol trafficking from the lysosome to mitochondria ameliorates hepatic lipotoxicity induced by aflatoxin B1 exposure.
Lin JX; Xu CY; Wu XM; Che L; Li TY; Mo SM; Guo DB; Lin ZN; Lin YC
Chemosphere; 2023 Apr; 320():138071. PubMed ID: 36754296
[TBL] [Abstract][Full Text] [Related]
9. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
Boadu E; Nelson RC; Francis GA
Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
[TBL] [Abstract][Full Text] [Related]
10. Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations.
Ramirez CM; Liu B; Aqul A; Taylor AM; Repa JJ; Turley SD; Dietschy JM
J Lipid Res; 2011 Apr; 52(4):688-98. PubMed ID: 21289032
[TBL] [Abstract][Full Text] [Related]
11. Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr
Jeurissen MLJ; Walenbergh SMA; Houben T; Gijbels MJJ; Li J; Hendrikx T; Oligschlaeger Y; van Gorp PJ; Binder CJ; Donners MMPC; Shiri-Sverdlov R
Atherosclerosis; 2016 Dec; 255():59-65. PubMed ID: 27816810
[TBL] [Abstract][Full Text] [Related]
12. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
Qian H; Wu X; Du X; Yao X; Zhao X; Lee J; Yang H; Yan N
Cell; 2020 Jul; 182(1):98-111.e18. PubMed ID: 32544384
[TBL] [Abstract][Full Text] [Related]
13. BORC-ARL8-HOPS ensemble is required for lysosomal cholesterol egress through NPC2.
Anderson J; Walker G; Pu J
Mol Biol Cell; 2022 Aug; 33(9):ar81. PubMed ID: 35653304
[TBL] [Abstract][Full Text] [Related]
14. NPC1, intracellular cholesterol trafficking and atherosclerosis.
Yu XH; Jiang N; Yao PB; Zheng XL; Cayabyab FS; Tang CK
Clin Chim Acta; 2014 Feb; 429():69-75. PubMed ID: 24296264
[TBL] [Abstract][Full Text] [Related]
15. Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.
Castellano BM; Thelen AM; Moldavski O; Feltes M; van der Welle RE; Mydock-McGrane L; Jiang X; van Eijkeren RJ; Davis OB; Louie SM; Perera RM; Covey DF; Nomura DK; Ory DS; Zoncu R
Science; 2017 Mar; 355(6331):1306-1311. PubMed ID: 28336668
[TBL] [Abstract][Full Text] [Related]
16. The point mutation of the cholesterol trafficking membrane protein NPC1 may affect its proper function in more than a single step: Molecular dynamics simulation study.
Yoon HJ; Jeong J; Kim G; Lee HH; Jang S
Comput Biol Chem; 2022 Aug; 99():107725. PubMed ID: 35850050
[TBL] [Abstract][Full Text] [Related]
17. Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway.
Dixit SS; Jadot M; Sohar I; Sleat DE; Stock AM; Lobel P
PLoS One; 2011; 6(8):e23677. PubMed ID: 21887293
[TBL] [Abstract][Full Text] [Related]
18. Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation.
Willenborg M; Schmidt CK; Braun P; Landgrebe J; von Figura K; Saftig P; Eskelinen EL
J Lipid Res; 2005 Dec; 46(12):2559-69. PubMed ID: 16177447
[TBL] [Abstract][Full Text] [Related]
19. Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.
Abi-Mosleh L; Infante RE; Radhakrishnan A; Goldstein JL; Brown MS
Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19316-21. PubMed ID: 19884502
[TBL] [Abstract][Full Text] [Related]
20. NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes.
Infante RE; Wang ML; Radhakrishnan A; Kwon HJ; Brown MS; Goldstein JL
Proc Natl Acad Sci U S A; 2008 Oct; 105(40):15287-92. PubMed ID: 18772377
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
