BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 34888851)

  • 21. Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel.
    Mori D; Ishida H; Mizuno T; Kusumoto S; Kondo Y; Izumi S; Nakata G; Nozaki Y; Maeda K; Sasaki Y; Fujita KI; Kusuhara H
    Drug Metab Dispos; 2020 May; 48(5):387-394. PubMed ID: 32114508
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Assessment of Clinical Drug-Drug Interactions of Elagolix, a Gonadotropin-Releasing Hormone Receptor Antagonist.
    Polepally AR; Ng JW; Salem AH; Dufek MB; Parikh A; Carter DC; Kamradt K; Mostafa NM; Shebley M
    J Clin Pharmacol; 2020 Dec; 60(12):1606-1616. PubMed ID: 33045114
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.
    Bechtold BJ; Lynch KD; Oyanna VO; Call MR; White LA; Graf TN; Oberlies NH; Clarke JD
    Drug Metab Dispos; 2024 Apr; 52(5):355-367. PubMed ID: 38485280
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Evaluation of Rifampin's Transporter Inhibitory and CYP3A Inductive Effects on the Pharmacokinetics of Venetoclax, a BCL-2 Inhibitor: Results of a Single- and Multiple-Dose Study.
    Agarwal SK; Hu B; Chien D; Wong SL; Salem AH
    J Clin Pharmacol; 2016 Nov; 56(11):1335-1343. PubMed ID: 26953185
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Further Evaluation of Coproporphyrins as Clinical Endogenous Markers for OATP1B.
    Feng S; Bo Q; Coleman HA; Charoin JE; Zhu M; Xiao J; Jin Y
    J Clin Pharmacol; 2021 Aug; 61(8):1027-1034. PubMed ID: 33460165
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist.
    Younis I; Weber E; Nelson C; Kirby BJ; Shen G; Xiao D; Watkins TR; Othman AA
    Clin Pharmacokinet; 2023 Apr; 62(4):609-621. PubMed ID: 36906733
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine.
    Lutz JD; Kirby BJ; Wang L; Song Q; Ling J; Massetto B; Worth A; Kearney BP; Mathias A
    Clin Pharmacol Ther; 2018 Dec; 104(6):1191-1198. PubMed ID: 29569712
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Drug-Drug Interaction of Letermovir and Atorvastatin in Healthy Participants.
    McCrea JB; Menzel K; Adedoyin A; Cho CR; Fox-Bosetti S; Macha S; Zhao T; Liu F; Panebianco D; Stoch SA; Iwamoto M
    Clin Pharmacol Drug Dev; 2022 Apr; 11(4):420-428. PubMed ID: 35157785
    [TBL] [Abstract][Full Text] [Related]  

  • 29. In vitro assessment of drug-drug interaction potential of boceprevir associated with drug metabolizing enzymes and transporters.
    Chu X; Cai X; Cui D; Tang C; Ghosal A; Chan G; Green MD; Kuo Y; Liang Y; Maciolek CM; Palamanda J; Evers R; Prueksaritanont T
    Drug Metab Dispos; 2013 Mar; 41(3):668-81. PubMed ID: 23293300
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease.
    Takita H; Scotcher D; Chu X; Yee KL; Ogungbenro K; Galetin A
    Clin Pharmacol Ther; 2022 Sep; 112(3):615-626. PubMed ID: 35652251
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment.
    Tatosian DA; Yee KL; Zhang Z; Mostoller K; Paul E; Sutradhar S; Larson P; Chhibber A; Wen J; Wang YJ; Lassman M; Latham AH; Pang J; Crumley T; Gillespie A; Marricco NC; Marenco T; Murphy M; Lasseter KC; Marbury TC; Tweedie D; Chu X; Evers R; Stoch SA
    Clin Pharmacol Ther; 2021 Feb; 109(2):403-415. PubMed ID: 32705692
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Developing a mechanistic understanding of the nonlinear pharmacokinetics of letermovir and prospective drug interaction with everolimus using physiological-based pharmacokinetic modeling.
    Menzel K; Kuo Y; Chen D; Hartmann G; Wang YH; Cho CR; McCrea JB; Asari K
    Clin Transl Sci; 2023 Jun; 16(6):1039-1048. PubMed ID: 37085998
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Pharmacokinetic Drug-Drug Interactions Between Letermovir and the Immunosuppressants Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolate Mofetil.
    McCrea JB; Macha S; Adedoyin A; Marshall W; Menzel K; Cho CR; Liu F; Zhao T; Levine V; Kraft WK; Yoon E; Panebianco D; Stoch SA; Iwamoto M
    J Clin Pharmacol; 2019 Oct; 59(10):1331-1339. PubMed ID: 30990905
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The Effect of Single and Multiple Doses of Rifampin on the Pharmacokinetics of Doravirine in Healthy Subjects.
    Yee KL; Khalilieh SG; Sanchez RI; Liu R; Anderson MS; Manthos H; Judge T; Brejda J; Butterton JR
    Clin Drug Investig; 2017 Jul; 37(7):659-667. PubMed ID: 28353169
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Effect of Rifampin-Mediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel.
    Schilling U; Dingemanse J; Voors-Pette C; Romeijn C; Dogterom P; Ufer M
    Clin Transl Sci; 2020 Sep; 13(5):886-890. PubMed ID: 32166864
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Quantitative prediction of OATP1B-mediated drug-drug interactions using endogenous biomarker coproporphyrin I.
    Takubo H; Bessho K; Watari R; Shigemi R
    Xenobiotica; 2022 Apr; 52(4):397-404. PubMed ID: 35638858
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The Role of Coproporphyrins As Endogenous Biomarkers for Organic Anion Transporting Polypeptide 1B Inhibition-Progress from 2016 to 2023.
    Lai Y
    Drug Metab Dispos; 2023 Aug; 51(8):950-961. PubMed ID: 37407093
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Pre-incubation with OATP1B1 and OATP1B3 inhibitors potentiates inhibitory effects in physiologically relevant sandwich-cultured primary human hepatocytes.
    Farasyn T; Pahwa S; Xu C; Yue W
    Eur J Pharm Sci; 2021 Oct; 165():105951. PubMed ID: 34311070
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers.
    Takehara I; Terashima H; Nakayama T; Yoshikado T; Yoshida M; Furihata K; Watanabe N; Maeda K; Ando O; Sugiyama Y; Kusuhara H
    Pharm Res; 2017 Aug; 34(8):1601-1614. PubMed ID: 28550384
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Biomarker-Informed Model-Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug-Drug Interactions.
    Kimoto E; Costales C; West MA; Bi YA; Vourvahis M; David Rodrigues A; Varma MVS
    Clin Pharmacol Ther; 2022 Feb; 111(2):404-415. PubMed ID: 34605015
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.