These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 34894691)

  • 1. Chemotherapeutics for
    Wu RZ; Zhou HY; Song JF; Xia QH; Hu W; Mou XD; Li X
    J Med Chem; 2021 Dec; 64(24):17627-17655. PubMed ID: 34894691
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase.
    Sharma H; Landau MJ; Sullivan TJ; Kumar VP; Dahlgren MK; Jorgensen WL; Anderson KS
    Bioorg Med Chem Lett; 2014 Feb; 24(4):1232-5. PubMed ID: 24440298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective peptide inhibitors of bifunctional thymidylate synthase-dihydrofolate reductase from Toxoplasma gondii provide insights into domain-domain communication and allosteric regulation.
    Landau MJ; Sharma H; Anderson KS
    Protein Sci; 2013 Sep; 22(9):1161-73. PubMed ID: 23813474
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular docking to Toxoplasma gondii thymidylate synthase-dihydrofolate reductase and efficacy of raltitrexed in infected mice.
    de Paula Reis M; de Lima DA; Pauli KB; Andreotti CEL; de Moraes ALS; Gonçalves DD; Navarro IT; Bueno PSA; Seixas FAV; Gasparotto Junior A; Lourenço ELB
    Parasitol Res; 2018 May; 117(5):1465-1471. PubMed ID: 29550996
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Toward rational design of species-specific inhibitors of Pneumocystis carinii thymidylate synthase and Toxoplasma gondii dihydrofolate reductase-thymidylate synthase.
    Peaslee KA; Anderson AC
    J Eukaryot Microbiol; 2001; Suppl():174S-175S. PubMed ID: 11906050
    [No Abstract]   [Full Text] [Related]  

  • 6. First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.
    Sharma H; Landau MJ; Vargo MA; Spasov KA; Anderson KS
    Biochemistry; 2013 Oct; 52(41):7305-7317. PubMed ID: 24053355
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein science "best paper" awards to Mark Landau and Brian Ziemba.
    Matthews BW
    Protein Sci; 2014 May; 23(5):515-6. PubMed ID: 24692246
    [No Abstract]   [Full Text] [Related]  

  • 8. Structural Insight into Effective Inhibitors' Binding to
    Vanichtanankul J; Yoomuang A; Taweechai S; Saeyang T; Pengon J; Yuvaniyama J; Tarnchompoo B; Yuthavong Y; Kamchonwongpaisan S
    ACS Chem Biol; 2022 Jul; 17(7):1691-1702. PubMed ID: 35715223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Evidence for a TS intermediate and TS half-sites reactivity.
    Johnson EF; Hinz W; Atreya CE; Maley F; Anderson KS
    J Biol Chem; 2002 Nov; 277(45):43126-36. PubMed ID: 12192007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii.
    Trujillo M; Donald RG; Roos DS; Greene PJ; Santi DV
    Biochemistry; 1996 May; 35(20):6366-74. PubMed ID: 8639582
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Primary structure of the dihydrofolate reductase-thymidylate synthase gene from Toxoplasma gondii.
    Roos DS
    J Biol Chem; 1993 Mar; 268(9):6269-80. PubMed ID: 8454599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bumped kinase inhibitor 1294 treats established Toxoplasma gondii infection.
    Doggett JS; Ojo KK; Fan E; Maly DJ; Van Voorhis WC
    Antimicrob Agents Chemother; 2014 Jun; 58(6):3547-9. PubMed ID: 24687502
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An updated review of chemical compounds with anti-Toxoplasma gondii activity.
    Rodriguez JB; Szajnman SH
    Eur J Med Chem; 2023 Dec; 262():115885. PubMed ID: 37871407
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Knocking down of the DHFR-TS gene in Toxoplasma gondii using siRNA and assessing the subsequences on toxoplasmosis in mice.
    Azimi-Resketi M; Eskandarian A; Ganjalikhani-Hakemi M; Zohrabi T
    Acta Trop; 2020 Jul; 207():105488. PubMed ID: 32277926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic Activity between Statins and Bisphosphonates against Acute Experimental Toxoplasmosis.
    Li ZH; Li C; Szajnman SH; Rodriguez JB; Moreno SNJ
    Antimicrob Agents Chemother; 2017 Aug; 61(8):. PubMed ID: 28559264
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A molecular docking strategy identifies Eosin B as a non-active site inhibitor of protozoal bifunctional thymidylate synthase-dihydrofolate reductase.
    Atreya CE; Johnson EF; Irwin JJ; Dow A; Massimine KM; Coppens I; Stempliuk V; Beverley S; Joiner KA; Shoichet BK; Anderson KS
    J Biol Chem; 2003 Apr; 278(16):14092-100. PubMed ID: 12556445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
    Vidadala RS; Rivas KL; Ojo KK; Hulverson MA; Zambriski JA; Bruzual I; Schultz TL; Huang W; Zhang Z; Scheele S; DeRocher AE; Choi R; Barrett LK; Siddaramaiah LK; Hol WG; Fan E; Merritt EA; Parsons M; Freiberg G; Marsh K; Kempf DJ; Carruthers VB; Isoherranen N; Doggett JS; Van Voorhis WC; Maly DJ
    J Med Chem; 2016 Jul; 59(13):6531-46. PubMed ID: 27309760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Perspective on current and emerging drugs in the treatment of acute and chronic toxoplasmosis.
    Lapinskas PJ; Ben-Harari RR
    Postgrad Med; 2019 Nov; 131(8):589-596. PubMed ID: 31399001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.
    Mui EJ; Schiehser GA; Milhous WK; Hsu H; Roberts CW; Kirisits M; Muench S; Rice D; Dubey JP; Fowble JW; Rathod PK; Queener SF; Liu SR; Jacobus DP; McLeod R
    PLoS Negl Trop Dis; 2008 Mar; 2(3):e190. PubMed ID: 18320016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of
    Alday PH; Nilsen A; Doggett JS
    Expert Opin Drug Discov; 2022 Sep; 17(9):997-1011. PubMed ID: 35772172
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.