159 related articles for article (PubMed ID: 34894957)
1. TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition.
Lee S; Park BB; Kwon H; Kim V; Jeon JS; Lee R; Subedi M; Lim T; Ha H; An D; Kim J; Kim D; Kim SK; Kim S; Byun Y
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):269-279. PubMed ID: 34894957
[TBL] [Abstract][Full Text] [Related]
2. Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors.
Puhl-Rubio AC; Stashko MA; Wang H; Hardy PB; Tyagi V; Li B; Wang X; Kireev D; Jessen HJ; Frye SV; Shears SB; Pearce KH
SLAS Discov; 2018 Oct; 23(9):982-988. PubMed ID: 29842835
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and characterization of novel isoform-selective IP6K1 inhibitors.
Wormald MM; Ernst G; Wei H; Barrow JC
Bioorg Med Chem Lett; 2019 Oct; 29(19):126628. PubMed ID: 31445853
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates.
Padmanabhan U; Dollins DE; Fridy PC; York JD; Downes CP
J Biol Chem; 2009 Apr; 284(16):10571-82. PubMed ID: 19208622
[TBL] [Abstract][Full Text] [Related]
5. Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases.
Mukherjee S; Haubner J; Chakraborty A
Molecules; 2020 Mar; 25(6):. PubMed ID: 32204420
[TBL] [Abstract][Full Text] [Related]
6. The Key Role of IP
Minini M; Senni A; Unfer V; Bizzarri M
Molecules; 2020 Sep; 25(19):. PubMed ID: 32992691
[TBL] [Abstract][Full Text] [Related]
7. Protein kinase- and lipase inhibitors of inositide metabolism deplete IP
Rajasekaran SS; Illies C; Shears SB; Wang H; Ayala TS; Martins JO; Daré E; Berggren PO; Barker CJ
Cell Signal; 2018 Jan; 42():127-133. PubMed ID: 29042286
[TBL] [Abstract][Full Text] [Related]
8. TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway.
Ghoshal S; Zhu Q; Asteian A; Lin H; Xu H; Ernst G; Barrow JC; Xu B; Cameron MD; Kamenecka TM; Chakraborty A
Mol Metab; 2016 Oct; 5(10):903-917. PubMed ID: 27689003
[TBL] [Abstract][Full Text] [Related]
9. Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.
Fu C; Xu J; Cheng W; Rojas T; Chin AC; Snowman AM; Harraz MM; Snyder SH
Proc Natl Acad Sci U S A; 2017 Feb; 114(8):2036-2041. PubMed ID: 28154132
[TBL] [Abstract][Full Text] [Related]
10. The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals.
Moritoh Y; Abe SI; Akiyama H; Kobayashi A; Koyama R; Hara R; Kasai S; Watanabe M
Nat Commun; 2021 Aug; 12(1):4847. PubMed ID: 34381031
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
Gu C; Stashko MA; Puhl-Rubio AC; Chakraborty M; Chakraborty A; Frye SV; Pearce KH; Wang X; Shears SB; Wang H
J Med Chem; 2019 Feb; 62(3):1443-1454. PubMed ID: 30624931
[TBL] [Abstract][Full Text] [Related]
12. The inositol pyrophosphate metabolism of Dictyostelium discoideum does not regulate inorganic polyphosphate (polyP) synthesis.
Desfougères Y; Portela-Torres P; Qiu D; Livermore TM; Harmel RK; Borghi F; Jessen HJ; Fiedler D; Saiardi A
Adv Biol Regul; 2022 Jan; 83():100835. PubMed ID: 34782304
[TBL] [Abstract][Full Text] [Related]
13. Selective inhibition of inositol hexakisphosphate kinases (IP6Ks) enhances mesenchymal stem cell engraftment and improves therapeutic efficacy for myocardial infarction.
Zhang Z; Liang D; Gao X; Zhao C; Qin X; Xu Y; Su T; Sun D; Li W; Wang H; Liu B; Cao F
Basic Res Cardiol; 2014 Jul; 109(4):417. PubMed ID: 24847908
[TBL] [Abstract][Full Text] [Related]
14. Inositol pyrophosphates and Akt/PKB: Is the pancreatic β-cell the exception to the rule?
Kim J; Darè E; Rajasekaran SS; Ryu SH; Berggren PO; Barker CJ
Cell Signal; 2019 Jun; 58():131-136. PubMed ID: 30742888
[TBL] [Abstract][Full Text] [Related]
15. Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups.
Draskovic P; Saiardi A; Bhandari R; Burton A; Ilc G; Kovacevic M; Snyder SH; Podobnik M
Chem Biol; 2008 Mar; 15(3):274-86. PubMed ID: 18355727
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors.
Ahn M; Park SE; Choi J; Choi J; Choi D; An D; Jeon H; Oh S; Lee K; Kim J; Jang J; Kim S; Byun Y
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2193866. PubMed ID: 37013838
[TBL] [Abstract][Full Text] [Related]
17. Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio.
Wundenberg T; Grabinski N; Lin H; Mayr GW
Biochem J; 2014 Aug; 462(1):173-84. PubMed ID: 24865181
[TBL] [Abstract][Full Text] [Related]
18. Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery.
Wang H; Godage HY; Riley AM; Weaver JD; Shears SB; Potter BV
Chem Biol; 2014 May; 21(5):689-99. PubMed ID: 24768307
[TBL] [Abstract][Full Text] [Related]
19. Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity.
Wormald M; Liao G; Kimos M; Barrow J; Wei H
PLoS One; 2017; 12(11):e0188852. PubMed ID: 29186181
[TBL] [Abstract][Full Text] [Related]
20. KO of 5-InsP
Gu C; Nguyen HN; Ganini D; Chen Z; Jessen HJ; Gu Z; Wang H; Shears SB
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):11968-11973. PubMed ID: 29078269
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
