BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 34899694)

  • 1. Treatment With the CSF1R Antagonist GW2580, Sensitizes Microglia to Reactive Oxygen Species.
    Soto-Diaz K; Vailati-Riboni M; Louie AY; McKim DB; Gaskins HR; Johnson RW; Steelman AJ
    Front Immunol; 2021; 12():734349. PubMed ID: 34899694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates.
    Poulen G; Aloy E; Bringuier CM; Mestre-Francés N; Artus EVF; Cardoso M; Perez JC; Goze-Bac C; Boukhaddaoui H; Lonjon N; Gerber YN; Perrin FE
    Theranostics; 2021; 11(18):8640-8659. PubMed ID: 34522204
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
    Neal ML; Fleming SM; Budge KM; Boyle AM; Kim C; Alam G; Beier EE; Wu LJ; Richardson JR
    FASEB J; 2020 Jan; 34(1):1679-1694. PubMed ID: 31914683
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves.
    Martínez-Muriana A; Mancuso R; Francos-Quijorna I; Olmos-Alonso A; Osta R; Perry VH; Navarro X; Gomez-Nicola D; López-Vales R
    Sci Rep; 2016 May; 6():25663. PubMed ID: 27174644
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
    Conway JG; McDonald B; Parham J; Keith B; Rusnak DW; Shaw E; Jansen M; Lin P; Payne A; Crosby RM; Johnson JH; Frick L; Lin MH; Depee S; Tadepalli S; Votta B; James I; Fuller K; Chambers TJ; Kull FC; Chamberlain SD; Hutchins JT
    Proc Natl Acad Sci U S A; 2005 Nov; 102(44):16078-83. PubMed ID: 16249345
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CSF1R blockade slows progression of cerebral hemorrhage by reducing microglial proliferation and increasing infiltration of CD8 + CD122+ T cells into the brain.
    Cheng F; Wang C; Yan B; Yin Z; Liu Y; Zhang L; Li M; Liao P; Gao H; Jia Z; Li D; Liu Q; Lei P
    Int Immunopharmacol; 2024 May; 133():112071. PubMed ID: 38636374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits.
    Henry RJ; Ritzel RM; Barrett JP; Doran SJ; Jiao Y; Leach JB; Szeto GL; Wu J; Stoica BA; Faden AI; Loane DJ
    J Neurosci; 2020 Apr; 40(14):2960-2974. PubMed ID: 32094203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CSF-1R inhibition attenuates renal and neuropsychiatric disease in murine lupus.
    Chalmers SA; Wen J; Shum J; Doerner J; Herlitz L; Putterman C
    Clin Immunol; 2017 Dec; 185():100-108. PubMed ID: 27570219
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.
    Obst J; Simon E; Martin-Estebane M; Pipi E; Barkwill LM; Gonzalez-Rivera I; Buchanan F; Prescott AR; Faust D; Fox S; Brownlees J; Taylor D; Perry VH; Nuthall H; Atkinson PJ; Karran E; Routledge C; Gomez-Nicola D
    Front Immunol; 2020; 11():579000. PubMed ID: 33162994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology.
    Olmos-Alonso A; Schetters ST; Sri S; Askew K; Mancuso R; Vargas-Caballero M; Holscher C; Perry VH; Gomez-Nicola D
    Brain; 2016 Mar; 139(Pt 3):891-907. PubMed ID: 26747862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Behavioral Sequelae of Social Defeat Require Microglia and Are Driven by Oxidative Stress in Mice.
    Lehmann ML; Weigel TK; Poffenberger CN; Herkenham M
    J Neurosci; 2019 Jul; 39(28):5594-5605. PubMed ID: 31085604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CSF1R antagonism limits local restimulation of antiviral CD8
    Funk KE; Klein RS
    J Neuroinflammation; 2019 Jan; 16(1):22. PubMed ID: 30704498
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Colony-stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma.
    Moon HG; Kim SJ; Lee MK; Kang H; Choi HS; Harijith A; Ren J; Natarajan V; Christman JW; Ackerman SJ; Park GY
    Allergy; 2020 Feb; 75(2):357-369. PubMed ID: 31385613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo.
    Liu Y; Given KS; Dickson EL; Owens GP; Macklin WB; Bennett JL
    Exp Neurol; 2019 Aug; 318():32-41. PubMed ID: 31029597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An Early Microglial Response Is Needed To Efficiently Control Herpes Simplex Virus Encephalitis.
    Uyar O; Laflamme N; Piret J; Venable MC; Carbonneau J; Zarrouk K; Rivest S; Boivin G
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32938766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine.
    da Silva MCM; Gomes GF; de Barros Fernandes H; da Silva AM; Teixeira AL; Moreira FA; de Miranda AS; de Oliveira ACP
    Sci Rep; 2021 Aug; 11(1):15989. PubMed ID: 34362959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of Macrophage Colony-Stimulating Factor Receptor on the Proliferation and Survival of Microglia Following Systemic Nerve and Cuprizone-Induced Injuries.
    Pons V; Laflamme N; Préfontaine P; Rivest S
    Front Immunol; 2020; 11():47. PubMed ID: 32082318
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
    Askew KE; Beverley J; Sigfridsson E; Szymkowiak S; Emelianova K; Dando O; Hardingham GE; Duncombe J; Hennessy E; Koudelka J; Samarasekera N; Salman RA; Smith C; Tavares AAS; Gomez-Nicola D; Kalaria RN; McColl BW; Horsburgh K
    Glia; 2024 Feb; 72(2):375-395. PubMed ID: 37909242
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.
    Moughon DL; He H; Schokrpur S; Jiang ZK; Yaqoob M; David J; Lin C; Iruela-Arispe ML; Dorigo O; Wu L
    Cancer Res; 2015 Nov; 75(22):4742-52. PubMed ID: 26471360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Depletion of embryonic microglia using the CSF1R inhibitor PLX5622 has adverse sex-specific effects on mice, including accelerated weight gain, hyperactivity and anxiolytic-like behaviour.
    Rosin JM; Vora SR; Kurrasch DM
    Brain Behav Immun; 2018 Oct; 73():682-697. PubMed ID: 30056204
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.