196 related articles for article (PubMed ID: 34902296)
1. EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway.
Qi X; Zhang S; Chen Z; Wang L; Zhu W; Yin C; Fan J; Wu X; Wang J; Guo C
Chem Biol Interact; 2022 Jan; 352():109773. PubMed ID: 34902296
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment.
Wang L; Guo C; Li X; Yu X; Li X; Xu K; Jiang B; Jia X; Li C; Shi D
Eur J Med Chem; 2019 Sep; 177():153-170. PubMed ID: 31132531
[TBL] [Abstract][Full Text] [Related]
3. Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro.
Wang J; Wang L; Zhang S; Fan J; Yang H; Li Q; Guo C
Int J Biol Macromol; 2020 Oct; 160():496-505. PubMed ID: 32479946
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma.
Liu Y; Sun L; Su X; Guo S
Biomed Pharmacother; 2016 Dec; 84():237-243. PubMed ID: 27662474
[TBL] [Abstract][Full Text] [Related]
5. The ERK-MNK-eIF4F signaling pathway mediates TPDHT-induced A549 cell death in vitro and in vivo.
Guo C; Hou Y; Yu X; Zhang F; Wu X; Wu X; Wang L
Food Chem Toxicol; 2020 Mar; 137():111158. PubMed ID: 31991197
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.
Konicek BW; Stephens JR; McNulty AM; Robichaud N; Peery RB; Dumstorf CA; Dowless MS; Iversen PW; Parsons S; Ellis KE; McCann DJ; Pelletier J; Furic L; Yingling JM; Stancato LF; Sonenberg N; Graff JR
Cancer Res; 2011 Mar; 71(5):1849-57. PubMed ID: 21233335
[TBL] [Abstract][Full Text] [Related]
7. CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q; Wang W; Luo J; Chu S; Chen L; Xu L; Zang H; Alnemah MM; Ma J; Fan S
Oncotarget; 2016 May; 7(19):27787-801. PubMed ID: 27050281
[TBL] [Abstract][Full Text] [Related]
8. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.
Fan S; Li Y; Yue P; Khuri FR; Sun SY
Neoplasia; 2010 Apr; 12(4):346-56. PubMed ID: 20360945
[TBL] [Abstract][Full Text] [Related]
9. The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex.
Chen L; Li G; Peng F; Jie X; Dongye G; Cai K; Feng R; Li B; Zeng Q; Lun K; Chen J; Xu B
Oncotarget; 2016 Dec; 7(49):80716-80734. PubMed ID: 27811372
[TBL] [Abstract][Full Text] [Related]
10. An-te-xiao capsule inhibits tumor growth in non-small cell lung cancer by targeting angiogenesis.
Han L; Wang JN; Cao XQ; Sun CX; Du X
Biomed Pharmacother; 2018 Dec; 108():941-951. PubMed ID: 30372906
[TBL] [Abstract][Full Text] [Related]
11. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
Moerke NJ; Aktas H; Chen H; Cantel S; Reibarkh MY; Fahmy A; Gross JD; Degterev A; Yuan J; Chorev M; Halperin JA; Wagner G
Cell; 2007 Jan; 128(2):257-67. PubMed ID: 17254965
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of eIF4E signaling by ribavirin selectively targets lung cancer and angiogenesis.
Tan H; He L; Cheng Z
Biochem Biophys Res Commun; 2020 Aug; 529(3):519-525. PubMed ID: 32736668
[TBL] [Abstract][Full Text] [Related]
13. Sulfated fucoidan FP08S2 inhibits lung cancer cell growth in vivo by disrupting angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling.
Chen H; Cong Q; Du Z; Liao W; Zhang L; Yao Y; Ding K
Cancer Lett; 2016 Nov; 382(1):44-52. PubMed ID: 27569654
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction.
Mahalingam P; Takrouri K; Chen T; Sahoo R; Papadopoulos E; Chen L; Wagner G; Aktas BH; Halperin JA; Chorev M
J Med Chem; 2014 Jun; 57(12):5094-111. PubMed ID: 24827861
[TBL] [Abstract][Full Text] [Related]
15. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
Zhou Y; Ma J; Zhang J; He L; Gong J; Long C
Oncol Rep; 2017 Jan; 37(1):313-322. PubMed ID: 28004121
[TBL] [Abstract][Full Text] [Related]
16. 5'-Cap‒Dependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma.
Srivastava RK; Khan J; Arumugam A; Muzaffar S; Guroji P; Gorbatyuk MS; Elmets CA; Slominski AT; Mukhtar MS; Athar M
J Invest Dermatol; 2021 Apr; 141(4):742-753.e10. PubMed ID: 32971126
[TBL] [Abstract][Full Text] [Related]
17. Targeting BRD4 proteins suppresses the growth of NSCLC through downregulation of eIF4E expression.
Gao Z; Yuan T; Zhou X; Ni P; Sun G; Li P; Cheng Z; Wang X
Cancer Biol Ther; 2018 May; 19(5):407-415. PubMed ID: 29333921
[TBL] [Abstract][Full Text] [Related]
18. 3-substituted indazoles as configurationally locked 4EGI-1 mimetics and inhibitors of the eIF4E/eIF4G interaction.
Yefidoff-Freedman R; Chen T; Sahoo R; Chen L; Wagner G; Halperin JA; Aktas BH; Chorev M
Chembiochem; 2014 Mar; 15(4):595-611. PubMed ID: 24458973
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E.
Ko SY; Guo H; Barengo N; Naora H
Clin Cancer Res; 2009 Jul; 15(13):4336-47. PubMed ID: 19458052
[TBL] [Abstract][Full Text] [Related]
20. eIF4E-eIF4G complex inhibition synergistically enhances the effect of sorafenib in hepatocellular carcinoma.
Fang C; Xie H; Zhao J; Wang W; Hou H; Zhang B; Zhou D; Geng X
Anticancer Drugs; 2021 Sep; 32(8):822-828. PubMed ID: 33783376
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]