183 related articles for article (PubMed ID: 34915026)
1. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer.
Lee WK; Maaß M; Quach A; Poscic N; Prangley H; Pallott EC; Kim JL; Pierce JS; Ogretmen B; Futerman AH; Thévenod F
J Biol Chem; 2022 Feb; 298(2):101492. PubMed ID: 34915026
[TBL] [Abstract][Full Text] [Related]
2. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
[TBL] [Abstract][Full Text] [Related]
3. Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides.
Trayssac M; Clarke CJ; Stith JL; Snider JM; Newen N; Gault CR; Hannun YA; Obeid LM
Cell Death Dis; 2021 Jan; 12(1):27. PubMed ID: 33414460
[TBL] [Abstract][Full Text] [Related]
4. Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide.
Yamaji T; Horie A; Tachida Y; Sakuma C; Suzuki Y; Kushi Y; Hanada K
Int J Mol Sci; 2016 Oct; 17(10):. PubMed ID: 27775668
[TBL] [Abstract][Full Text] [Related]
5. Modulation of ceramide synthase activity via dimerization.
Laviad EL; Kelly S; Merrill AH; Futerman AH
J Biol Chem; 2012 Jun; 287(25):21025-33. PubMed ID: 22539345
[TBL] [Abstract][Full Text] [Related]
6. The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.
Hartmann D; Wegner MS; Wanger RA; Ferreirós N; Schreiber Y; Lucks J; Schiffmann S; Geisslinger G; Grösch S
Int J Biochem Cell Biol; 2013 Jul; 45(7):1195-203. PubMed ID: 23538298
[TBL] [Abstract][Full Text] [Related]
7. Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases.
Kim YR; Lee EJ; Shin KO; Kim MH; Pewzner-Jung Y; Lee YM; Park JW; Futerman AH; Park WJ
Exp Mol Med; 2019 Nov; 51(11):1-16. PubMed ID: 31676768
[TBL] [Abstract][Full Text] [Related]
8. Ceramide synthase 2 deletion decreases the infectivity of HIV-1.
Barklis E; Alfadhli A; Kyle JE; Bramer LM; Bloodsworth KJ; Barklis RL; Leier HC; Petty RM; Zelnik ID; Metz TO; Futerman AH; Tafesse FG
J Biol Chem; 2021; 296():100340. PubMed ID: 33515546
[TBL] [Abstract][Full Text] [Related]
9. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
Mullen TD; Spassieva S; Jenkins RW; Kitatani K; Bielawski J; Hannun YA; Obeid LM
J Lipid Res; 2011 Jan; 52(1):68-77. PubMed ID: 20940143
[TBL] [Abstract][Full Text] [Related]
10. Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer.
Jang SW; Park WJ; Min H; Kwon TK; Baek SK; Hwang I; Kim S; Park JW
Oncol Rep; 2018 Dec; 40(6):3489-3500. PubMed ID: 30272337
[TBL] [Abstract][Full Text] [Related]
11. Ceramide synthase 2-C
Zhang X; Sakamoto W; Canals D; Ishibashi M; Matsuda M; Nishida K; Toyoshima M; Shigeta S; Taniguchi M; Senkal CE; Okazaki T; Yaegashi N; Hannun YA; Nabe T; Kitatani K
FASEB J; 2021 Feb; 35(2):e21287. PubMed ID: 33423335
[TBL] [Abstract][Full Text] [Related]
12. Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.
Senkal CE; Ponnusamy S; Manevich Y; Meyers-Needham M; Saddoughi SA; Mukhopadyay A; Dent P; Bielawski J; Ogretmen B
J Biol Chem; 2011 Dec; 286(49):42446-42458. PubMed ID: 22013072
[TBL] [Abstract][Full Text] [Related]
13. Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
Verlekar D; Wei SJ; Cho H; Yang S; Kang MH
Cell Death Dis; 2018 Sep; 9(9):925. PubMed ID: 30206207
[TBL] [Abstract][Full Text] [Related]
14. Long-Chain and Very Long-Chain Ceramides Mediate Doxorubicin-Induced Toxicity and Fibrosis.
Kretzschmar T; Bekhite MM; Wu JMF; Haase D; Förster M; Müller T; Nietzsche S; Westermann M; Franz M; Gräler MH; Schulze PC
Int J Mol Sci; 2021 Nov; 22(21):. PubMed ID: 34769283
[TBL] [Abstract][Full Text] [Related]
15. Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment.
Frangioudakis G; Diakanastasis B; Liao BQ; Saville JT; Hoffman NJ; Mitchell TW; Schmitz-Peiffer C
Diabetologia; 2013 Dec; 56(12):2697-701. PubMed ID: 23989724
[TBL] [Abstract][Full Text] [Related]
16. Eleven residues determine the acyl chain specificity of ceramide synthases.
Tidhar R; Zelnik ID; Volpert G; Ben-Dor S; Kelly S; Merrill AH; Futerman AH
J Biol Chem; 2018 Jun; 293(25):9912-9921. PubMed ID: 29632068
[TBL] [Abstract][Full Text] [Related]
17. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.
Laviad EL; Albee L; Pankova-Kholmyansky I; Epstein S; Park H; Merrill AH; Futerman AH
J Biol Chem; 2008 Feb; 283(9):5677-84. PubMed ID: 18165233
[TBL] [Abstract][Full Text] [Related]
18. Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.
Sassa T; Hirayama T; Kihara A
J Biol Chem; 2016 Apr; 291(14):7477-87. PubMed ID: 26887952
[TBL] [Abstract][Full Text] [Related]
19. Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis.
Stiban J; Perera M
Biochim Biophys Acta; 2015 Feb; 1848(2):561-7. PubMed ID: 25462172
[TBL] [Abstract][Full Text] [Related]
20. Oncogenic PITX2 facilitates tumor cell drug resistance by inverse regulation of hOCT3/SLC22A3 and ABC drug transporters in colon and kidney cancers.
Lee WK; Thévenod F
Cancer Lett; 2019 May; 449():237-251. PubMed ID: 30742940
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
