260 related articles for article (PubMed ID: 34919689)
1. A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease.
Kandimalla R; Manczak M; Pradeepkiran JA; Morton H; Reddy PH
Hum Mol Genet; 2022 Jun; 31(11):1788-1805. PubMed ID: 34919689
[TBL] [Abstract][Full Text] [Related]
2. Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Manczak M; Kandimalla R; Yin X; Reddy PH
Hum Mol Genet; 2018 Apr; 27(8):1332-1342. PubMed ID: 29408999
[TBL] [Abstract][Full Text] [Related]
3. A partial reduction of VDAC1 enhances mitophagy, autophagy, synaptic activities in a transgenic Tau mouse model.
Vijayan M; Alvir RV; Alvir RV; Bunquin LE; Pradeepkiran JA; Reddy PH
Aging Cell; 2022 Aug; 21(8):e13663. PubMed ID: 35801276
[TBL] [Abstract][Full Text] [Related]
4. Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Kandimalla R; Manczak M; Fry D; Suneetha Y; Sesaki H; Reddy PH
Hum Mol Genet; 2016 Nov; 25(22):4881-4897. PubMed ID: 28173111
[TBL] [Abstract][Full Text] [Related]
5. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer's disease.
Reddy AP; Sawant N; Morton H; Kshirsagar S; Bunquin LE; Yin X; Reddy PH
Hum Mol Genet; 2021 May; 30(9):789-810. PubMed ID: 33791799
[TBL] [Abstract][Full Text] [Related]
6. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
[TBL] [Abstract][Full Text] [Related]
7. Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer's Disease.
Reddy PH; Oliver DM
Cells; 2019 May; 8(5):. PubMed ID: 31121890
[TBL] [Abstract][Full Text] [Related]
8. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Kandimalla R; Manczak M; Yin X; Wang R; Reddy PH
Hum Mol Genet; 2018 Jan; 27(1):30-40. PubMed ID: 29040533
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
[TBL] [Abstract][Full Text] [Related]
10. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Reddy PH; Yin X; Manczak M; Kumar S; Pradeepkiran JA; Vijayan M; Reddy AP
Hum Mol Genet; 2018 Jul; 27(14):2502-2516. PubMed ID: 29701781
[TBL] [Abstract][Full Text] [Related]
11. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Manczak M; Reddy PH
Hum Mol Genet; 2012 Jun; 21(11):2538-47. PubMed ID: 22367970
[TBL] [Abstract][Full Text] [Related]
12. Mitochondrial dysfunction, mitophagy, and role of dynamin-related protein 1 in Alzheimer's disease.
Medala VK; Gollapelli B; Dewanjee S; Ogunmokun G; Kandimalla R; Vallamkondu J
J Neurosci Res; 2021 Apr; 99(4):1120-1135. PubMed ID: 33465841
[TBL] [Abstract][Full Text] [Related]
13. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Manczak M; Calkins MJ; Reddy PH
Hum Mol Genet; 2011 Jul; 20(13):2495-509. PubMed ID: 21459773
[TBL] [Abstract][Full Text] [Related]
14. Targeting dynamin-related protein-1 as a potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease.
Bhatti JS; Kaur S; Mishra J; Dibbanti H; Singh A; Reddy AP; Bhatti GK; Reddy PH
Biochim Biophys Acta Mol Basis Dis; 2023 Oct; 1869(7):166798. PubMed ID: 37392948
[TBL] [Abstract][Full Text] [Related]
15. Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimer's disease.
Bera A; Lavanya G; Reshmi R; Dev K; Kumar R
Eur J Neurosci; 2022 Nov; 56(9):5516-5531. PubMed ID: 35078269
[TBL] [Abstract][Full Text] [Related]
16. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse.
Morton H; Kshirsagar S; Orlov E; Bunquin LE; Sawant N; Boleng L; George M; Basu T; Ramasubramanian B; Pradeepkiran JA; Kumar S; Vijayan M; Reddy AP; Reddy PH
Free Radic Biol Med; 2021 Aug; 172():652-667. PubMed ID: 34246776
[TBL] [Abstract][Full Text] [Related]
17. Early Cellular, Molecular, Morphological and Behavioral Changes in the Humanized Amyloid-Beta-Knock-In Mouse Model of Late-Onset Alzheimer's Disease.
Kshirsagar S; Alvir RV; Hindle A; Kumar S; Vijayan M; Pradeepkiran JA; Reddy AP; Ramasubramanian B; Reddy PH
Cells; 2022 Feb; 11(4):. PubMed ID: 35203382
[TBL] [Abstract][Full Text] [Related]
18. Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer's disease.
Reddy AP; Yin X; Sawant N; Reddy PH
Hum Mol Genet; 2021 May; 30(10):847-864. PubMed ID: 33615359
[TBL] [Abstract][Full Text] [Related]
19. Protective effects of a small molecule inhibitor, DDQ against amyloid beta in Alzheimer's disease.
Vijayan M; Bose C; Reddy PH
Mitochondrion; 2021 Jul; 59():17-29. PubMed ID: 33839321
[TBL] [Abstract][Full Text] [Related]
20. Are mitophagy enhancers therapeutic targets for Alzheimer's disease?
Pradeepkiran JA; Hindle A; Kshirsagar S; Reddy PH
Biomed Pharmacother; 2022 May; 149():112918. PubMed ID: 35585708
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]