141 related articles for article (PubMed ID: 34928138)
1. Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
Ayoub A; Park SH; Lee YT; Cho US; Dou Y
Biochemistry; 2022 Jan; 61(1):1-9. PubMed ID: 34928138
[TBL] [Abstract][Full Text] [Related]
2. Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Park SH; Ayoub A; Lee YT; Xu J; Kim H; Zheng W; Zhang B; Sha L; An S; Zhang Y; Cianfrocco MA; Su M; Dou Y; Cho US
Nat Commun; 2019 Dec; 10(1):5540. PubMed ID: 31804488
[TBL] [Abstract][Full Text] [Related]
3. Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Xue H; Yao T; Cao M; Zhu G; Li Y; Yuan G; Chen Y; Lei M; Huang J
Nature; 2019 Sep; 573(7774):445-449. PubMed ID: 31485071
[TBL] [Abstract][Full Text] [Related]
4. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
Patel A; Vought VE; Swatkoski S; Viggiano S; Howard B; Dharmarajan V; Monteith KE; Kupakuwana G; Namitz KE; Shinsky SA; Cotter RJ; Cosgrove MS
J Biol Chem; 2014 Jan; 289(2):868-84. PubMed ID: 24235145
[TBL] [Abstract][Full Text] [Related]
5. The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
Han J; Li T; Li Y; Li M; Wang X; Peng C; Su C; Li N; Li Y; Xu Y; Chen Y
Nucleic Acids Res; 2019 Nov; 47(19):10426-10438. PubMed ID: 31544921
[TBL] [Abstract][Full Text] [Related]
6. On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A; Dharmarajan V; Vought VE; Cosgrove MS
J Biol Chem; 2009 Sep; 284(36):24242-56. PubMed ID: 19556245
[TBL] [Abstract][Full Text] [Related]
7. A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A; Vought VE; Dharmarajan V; Cosgrove MS
J Biol Chem; 2011 Feb; 286(5):3359-69. PubMed ID: 21106533
[TBL] [Abstract][Full Text] [Related]
8. Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Lee YT; Ayoub A; Park SH; Sha L; Xu J; Mao F; Zheng W; Zhang Y; Cho US; Dou Y
Nat Commun; 2021 May; 12(1):2953. PubMed ID: 34012049
[TBL] [Abstract][Full Text] [Related]
9. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
Wiersma M; Bussiere M; Halsall JA; Turan N; Slany R; Turner BM; Nightingale KP
Epigenetics Chromatin; 2016; 9():52. PubMed ID: 27895715
[TBL] [Abstract][Full Text] [Related]
10. Structural insights on the KMT2-NCP interaction.
Yang Z; Zepeda R; Dou Y
Biochem Soc Trans; 2023 Feb; 51(1):427-434. PubMed ID: 36695549
[TBL] [Abstract][Full Text] [Related]
11. Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Rahman S; Hoffmann NA; Worden EJ; Smith ML; Namitz KEW; Knutson BA; Cosgrove MS; Wolberger C
Proc Natl Acad Sci U S A; 2022 Sep; 119(38):e2205691119. PubMed ID: 36095189
[TBL] [Abstract][Full Text] [Related]
12. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.
Cao F; Chen Y; Cierpicki T; Liu Y; Basrur V; Lei M; Dou Y
PLoS One; 2010 Nov; 5(11):e14102. PubMed ID: 21124902
[TBL] [Abstract][Full Text] [Related]
13. Regulation of MLL1 H3K4 methyltransferase activity by its core components.
Dou Y; Milne TA; Ruthenburg AJ; Lee S; Lee JW; Verdine GL; Allis CD; Roeder RG
Nat Struct Mol Biol; 2006 Aug; 13(8):713-9. PubMed ID: 16878130
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
Dharmarajan V; Lee JH; Patel A; Skalnik DG; Cosgrove MS
J Biol Chem; 2012 Aug; 287(33):27275-89. PubMed ID: 22665483
[TBL] [Abstract][Full Text] [Related]
15. High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.
Li DD; Chen WL; Wang ZH; Xie YY; Xu XL; Jiang ZY; Zhang XJ; You QD; Guo XK
Eur J Med Chem; 2016 Nov; 124():480-489. PubMed ID: 27598236
[TBL] [Abstract][Full Text] [Related]
16. Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.
Cosgrove MS; Patel A
FEBS J; 2010 Apr; 277(8):1832-42. PubMed ID: 20236310
[TBL] [Abstract][Full Text] [Related]
17. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
Wang P; Lin C; Smith ER; Guo H; Sanderson BW; Wu M; Gogol M; Alexander T; Seidel C; Wiedemann LM; Ge K; Krumlauf R; Shilatifard A
Mol Cell Biol; 2009 Nov; 29(22):6074-85. PubMed ID: 19703992
[TBL] [Abstract][Full Text] [Related]
18. Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
Patel A; Dharmarajan V; Cosgrove MS
J Biol Chem; 2008 Nov; 283(47):32158-61. PubMed ID: 18829459
[TBL] [Abstract][Full Text] [Related]
19. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
Cao F; Townsend EC; Karatas H; Xu J; Li L; Lee S; Liu L; Chen Y; Ouillette P; Zhu J; Hess JL; Atadja P; Lei M; Qin ZS; Malek S; Wang S; Dou Y
Mol Cell; 2014 Jan; 53(2):247-61. PubMed ID: 24389101
[TBL] [Abstract][Full Text] [Related]
20. A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.
Shinsky SA; Hu M; Vought VE; Ng SB; Bamshad MJ; Shendure J; Cosgrove MS
J Mol Biol; 2014 Jun; 426(12):2283-99. PubMed ID: 24680668
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]