141 related articles for article (PubMed ID: 34928138)
21. Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.
Jakovcevski M; Ruan H; Shen EY; Dincer A; Javidfar B; Ma Q; Peter CJ; Cheung I; Mitchell AC; Jiang Y; Lin CL; Pothula V; Stewart AF; Ernst P; Yao WD; Akbarian S
J Neurosci; 2015 Apr; 35(13):5097-108. PubMed ID: 25834037
[TBL] [Abstract][Full Text] [Related]
22. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.
Karatas H; Townsend EC; Bernard D; Dou Y; Wang S
J Med Chem; 2010 Jul; 53(14):5179-85. PubMed ID: 20575550
[TBL] [Abstract][Full Text] [Related]
23. Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance.
Huo H; Magro PG; Pietsch EC; Patel BB; Scotto KW
Cancer Res; 2010 Nov; 70(21):8726-35. PubMed ID: 20861184
[TBL] [Abstract][Full Text] [Related]
24. Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1.
Luan Y; Blazer LL; Hu H; Hajian T; Zhang J; Wu H; Houliston S; Arrowsmith CH; Vedadi M; Zheng YG
Org Biomol Chem; 2016 Jan; 14(2):631-638. PubMed ID: 26541578
[TBL] [Abstract][Full Text] [Related]
25. Structure-based design and synthesis of small molecular inhibitors disturbing the interaction of MLL1-WDR5.
Li DD; Chen WL; Xu XL; Jiang F; Wang L; Xie YY; Zhang XJ; Guo XK; You QD; Sun HP
Eur J Med Chem; 2016 Aug; 118():1-8. PubMed ID: 27116709
[TBL] [Abstract][Full Text] [Related]
26. The histone methyltransferase MLL1 permits the oscillation of circadian gene expression.
Katada S; Sassone-Corsi P
Nat Struct Mol Biol; 2010 Dec; 17(12):1414-21. PubMed ID: 21113167
[TBL] [Abstract][Full Text] [Related]
27. Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Ruthenburg AJ; Wang W; Graybosch DM; Li H; Allis CD; Patel DJ; Verdine GL
Nat Struct Mol Biol; 2006 Aug; 13(8):704-12. PubMed ID: 16829959
[TBL] [Abstract][Full Text] [Related]
28. Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.
Avdic V; Zhang P; Lanouette S; Voronova A; Skerjanc I; Couture JF
FASEB J; 2011 Mar; 25(3):960-7. PubMed ID: 21135039
[TBL] [Abstract][Full Text] [Related]
29. Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.
Shinsky SA; Monteith KE; Viggiano S; Cosgrove MS
J Biol Chem; 2015 Mar; 290(10):6361-75. PubMed ID: 25561738
[TBL] [Abstract][Full Text] [Related]
30. Insights on the regulation of the MLL/SET1 family histone methyltransferases.
Sha L; Ayoub A; Cho US; Dou Y
Biochim Biophys Acta Gene Regul Mech; 2020 Jul; 1863(7):194561. PubMed ID: 32304759
[TBL] [Abstract][Full Text] [Related]
31. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
Alicea-Velázquez NL; Shinsky SA; Loh DM; Lee JH; Skalnik DG; Cosgrove MS
J Biol Chem; 2016 Oct; 291(43):22357-22372. PubMed ID: 27563068
[TBL] [Abstract][Full Text] [Related]
32. PAQR3 modulates H3K4 trimethylation by spatial modulation of the regulatory subunits of COMPASS-like complexes in mammalian cells.
Liu C; Zhang Y; Hou Y; Shen L; Li Y; Guo W; Xu D; Liu G; Zhao Z; Man K; Pan Y; Wang Z; Chen Y
Biochem J; 2015 May; 467(3):415-24. PubMed ID: 25706881
[TBL] [Abstract][Full Text] [Related]
33. RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
Blatter M; Meylan C; Cléry A; Giambruno R; Nikolaev Y; Heidecker M; Solanki JA; Diaz MO; Gabellini D; Allain FH
Sci Adv; 2023 Apr; 9(16):eadf5330. PubMed ID: 37075125
[TBL] [Abstract][Full Text] [Related]
34. Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy.
Wang ZH; Li DD; Chen WL; You QD; Guo XK
Bioorg Med Chem; 2018 Jan; 26(2):356-365. PubMed ID: 29254892
[TBL] [Abstract][Full Text] [Related]
35. Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.
Weirich S; Kudithipudi S; Jeltsch A
Mol Oncol; 2017 Apr; 11(4):373-387. PubMed ID: 28182322
[TBL] [Abstract][Full Text] [Related]
36. Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.
Namitz KEW; Tan S; Cosgrove MS
J Biol Chem; 2023 Feb; 299(2):102874. PubMed ID: 36623730
[TBL] [Abstract][Full Text] [Related]
37. MLL1 inhibition reduces IgM levels in Waldenström macroglobulinemia.
Karbalivand M; Almada LL; Ansell SM; Fernandez-Zapico ME; Elsawa SF
Leuk Res; 2022 May; 116():106841. PubMed ID: 35462170
[TBL] [Abstract][Full Text] [Related]
38. The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat J; Heuberger J; Vidal RO; Goveas N; Kosel F; Berenguer-Llergo A; Kranz A; Wulf-Goldenberg A; Behrens D; Melcher B; Sauer S; Vieth M; Batlle E; Stewart AF; Birchmeier W
Nat Commun; 2020 Dec; 11(1):6422. PubMed ID: 33349639
[TBL] [Abstract][Full Text] [Related]
39. MLL1 is regulated by KSHV LANA and is important for virus latency.
Tan M; Li S; Juillard F; Chitas R; Custódio TF; Xue H; Szymula A; Sun Q; Liu B; Álvarez ÁL; Chen S; Huang J; Simas JP; McVey CE; Kaye KM
Nucleic Acids Res; 2021 Dec; 49(22):12895-12911. PubMed ID: 34850113
[TBL] [Abstract][Full Text] [Related]
40. MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.
Wang X; Zhu K; Li S; Liao Y; Du R; Zhang X; Shu HB; Guo AY; Li L; Wu M
J Cell Sci; 2012 Sep; 125(Pt 17):4058-66. PubMed ID: 22623725
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
