BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 34932122)

  • 1. Role of plakophilin-2 expression on exercise-related progression of arrhythmogenic right ventricular cardiomyopathy: a translational study.
    Cerrone M; Marrón-Liñares GM; van Opbergen CJM; Costa S; Bourfiss M; Pérez-Hernández M; Schlamp F; Sanchis-Gomar F; Malkani K; Drenkova K; Zhang M; Lin X; Heguy A; Velthuis BK; Prakken NHJ; LaGerche A; Calkins H; James CA; Te Riele ASJM; Delmar M
    Eur Heart J; 2022 Mar; 43(12):1251-1264. PubMed ID: 34932122
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of Ca
    Kim JC; Pérez-Hernández M; Alvarado FJ; Maurya SR; Montnach J; Yin Y; Zhang M; Lin X; Vasquez C; Heguy A; Liang FX; Woo SH; Morley GE; Rothenberg E; Lundby A; Valdivia HH; Cerrone M; Delmar M
    Circulation; 2019 Sep; 140(12):1015-1030. PubMed ID: 31315456
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts.
    van Opbergen CJM; Bagwan N; Maurya SR; Kim JC; Smith AN; Blackwell DJ; Johnston JN; Knollmann BC; Cerrone M; Lundby A; Delmar M
    Circulation; 2022 May; 145(19):1480-1496. PubMed ID: 35491884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC.
    Pérez-Hernández M; van Opbergen CJM; Bagwan N; Vissing CR; Marrón-Liñares GM; Zhang M; Torres Vega E; Sorrentino A; Drici L; Sulek K; Zhai R; Hansen FB; Christensen AH; Boesgaard S; Gustafsson F; Rossing K; Small EM; Davies MJ; Rothenberg E; Sato PY; Cerrone M; Jensen THL; Qvortrup K; Bundgaard H; Delmar M; Lundby A
    Circulation; 2022 Sep; 146(11):851-867. PubMed ID: 35959657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exercise triggers ARVC phenotype in mice expressing a disease-causing mutated version of human plakophilin-2.
    Cruz FM; Sanz-Rosa D; Roche-Molina M; García-Prieto J; García-Ruiz JM; Pizarro G; Jiménez-Borreguero LJ; Torres M; Bernad A; Ruíz-Cabello J; Fuster V; Ibáñez B; Bernal JA
    J Am Coll Cardiol; 2015 Apr; 65(14):1438-50. PubMed ID: 25857910
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the molecular phenotype of two arrhythmogenic right ventricular cardiomyopathy (ARVC)-related plakophilin-2 (PKP2) mutations.
    Joshi-Mukherjee R; Coombs W; Musa H; Oxford E; Taffet S; Delmar M
    Heart Rhythm; 2008 Dec; 5(12):1715-23. PubMed ID: 19084810
    [TBL] [Abstract][Full Text] [Related]  

  • 7. AAV-Mediated Delivery of Plakophilin-2a Arrests Progression of Arrhythmogenic Right Ventricular Cardiomyopathy in Murine Hearts: Preclinical Evidence Supporting Gene Therapy in Humans.
    van Opbergen CJM; Narayanan B; Sacramento CB; Stiles KM; Mishra V; Frenk E; Ricks D; Chen G; Zhang M; Yarabe P; Schwartz J; Delmar M; Herzog CD; Cerrone M
    Circ Genom Precis Med; 2024 Feb; 17(1):e004305. PubMed ID: 38288614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High risk of heart failure associated with desmoglein-2 mutations compared to plakophilin-2 mutations in arrhythmogenic right ventricular cardiomyopathy/dysplasia.
    Hermida A; Fressart V; Hidden-Lucet F; Donal E; Probst V; Deharo JC; Chevalier P; Klug D; Mansencal N; Delacretaz E; Cosnay P; Scanu P; Extramiana F; Keller DI; Rouanet S; Charron P; Gandjbakhch E
    Eur J Heart Fail; 2019 Jun; 21(6):792-800. PubMed ID: 30790397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype.
    Cerrone M; Lin X; Zhang M; Agullo-Pascual E; Pfenniger A; Chkourko Gusky H; Novelli V; Kim C; Tirasawadichai T; Judge DP; Rothenberg E; Chen HS; Napolitano C; Priori SG; Delmar M
    Circulation; 2014 Mar; 129(10):1092-103. PubMed ID: 24352520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells.
    Caspi O; Huber I; Gepstein A; Arbel G; Maizels L; Boulos M; Gepstein L
    Circ Cardiovasc Genet; 2013 Dec; 6(6):557-68. PubMed ID: 24200905
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
    Cerrone M; Noorman M; Lin X; Chkourko H; Liang FX; van der Nagel R; Hund T; Birchmeier W; Mohler P; van Veen TA; van Rijen HV; Delmar M
    Cardiovasc Res; 2012 Sep; 95(4):460-8. PubMed ID: 22764151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
    Kirchner F; Schuetz A; Boldt LH; Martens K; Dittmar G; Haverkamp W; Thierfelder L; Heinemann U; Gerull B
    Circ Cardiovasc Genet; 2012 Aug; 5(4):400-11. PubMed ID: 22781308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
    Gerull B; Heuser A; Wichter T; Paul M; Basson CT; McDermott DA; Lerman BB; Markowitz SM; Ellinor PT; MacRae CA; Peters S; Grossmann KS; Drenckhahn J; Michely B; Sasse-Klaassen S; Birchmeier W; Dietz R; Breithardt G; Schulze-Bahr E; Thierfelder L
    Nat Genet; 2004 Nov; 36(11):1162-4. PubMed ID: 15489853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pathogenic variants in plakophilin-2 gene (PKP2) are associated with better survival in arrhythmogenic right ventricular cardiomyopathy.
    Biernacka EK; Borowiec K; Franaszczyk M; Szperl M; Rampazzo A; Woźniak O; Roszczynko M; Śmigielski W; Lutyńska A; Hoffman P
    J Appl Genet; 2021 Dec; 62(4):613-620. PubMed ID: 34191271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations.
    Fidler LM; Wilson GJ; Liu F; Cui X; Scherer SW; Taylor GP; Hamilton RM
    J Cell Mol Med; 2009 Oct; 13(10):4219-28. PubMed ID: 18662195
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Truncating plakophilin-2 mutations in arrhythmogenic cardiomyopathy are associated with protein haploinsufficiency in both myocardium and epidermis.
    Rasmussen TB; Nissen PH; Palmfeldt J; Gehmlich K; Dalager S; Jensen UB; Kim WY; Heickendorff L; Mølgaard H; Jensen HK; Baandrup UT; Bross P; Mogensen J
    Circ Cardiovasc Genet; 2014 Jun; 7(3):230-40. PubMed ID: 24704780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arrhythmogenic right ventricular cardiomyopathy due to a novel plakophilin 2 mutation: wide spectrum of disease in mutation carriers within a family.
    Kannankeril PJ; Bhuiyan ZA; Darbar D; Mannens MM; Wilde AA; Roden DM
    Heart Rhythm; 2006 Aug; 3(8):939-44. PubMed ID: 16876743
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy.
    Pilichou K; Nava A; Basso C; Beffagna G; Bauce B; Lorenzon A; Frigo G; Vettori A; Valente M; Towbin J; Thiene G; Danieli GA; Rampazzo A
    Circulation; 2006 Mar; 113(9):1171-9. PubMed ID: 16505173
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion.
    Sonoda K; Ohno S; Otuki S; Kato K; Yagihara N; Watanabe H; Makiyama T; Minamino T; Horie M
    Europace; 2017 Apr; 19(4):644-650. PubMed ID: 28431057
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.
    Cerrone M; Montnach J; Lin X; Zhao YT; Zhang M; Agullo-Pascual E; Leo-Macias A; Alvarado FJ; Dolgalev I; Karathanos TV; Malkani K; Van Opbergen CJM; van Bavel JJA; Yang HQ; Vasquez C; Tester D; Fowler S; Liang F; Rothenberg E; Heguy A; Morley GE; Coetzee WA; Trayanova NA; Ackerman MJ; van Veen TAB; Valdivia HH; Delmar M
    Nat Commun; 2017 Jul; 8(1):106. PubMed ID: 28740174
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.