209 related articles for article (PubMed ID: 34936539)
1. SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain.
Yin P; Bai D; Deng F; Zhang C; Jia Q; Zhu L; Chen L; Li B; Guo X; Ye J; Tan Z; Wang L; Li S; Li XJ
Autophagy; 2022 Aug; 18(8):1955-1968. PubMed ID: 34936539
[TBL] [Abstract][Full Text] [Related]
2. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S; Jeon YM; Cha SJ; Kim S; Kwon Y; Jo M; Jang YN; Lee S; Kim J; Kim SR; Lee KJ; Lee SB; Kim K; Kim HJ
Autophagy; 2020 Aug; 16(8):1396-1412. PubMed ID: 31690171
[TBL] [Abstract][Full Text] [Related]
3. Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43.
Donde A; Sun M; Jeong YH; Wen X; Ling J; Lin S; Braunstein K; Nie S; Wang S; Chen L; Wong PC
Autophagy; 2020 Apr; 16(4):672-682. PubMed ID: 31242080
[TBL] [Abstract][Full Text] [Related]
4. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z; Lim J; Wang Q; Purtell K; Wu S; Palomo GM; Tan H; Manfredi G; Zhao Y; Peng J; Hu B; Chen S; Yue Z
Autophagy; 2020 May; 16(5):917-931. PubMed ID: 31362587
[TBL] [Abstract][Full Text] [Related]
5. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Xu Y; Zhang S; Zheng H
Autophagy; 2019 Apr; 15(4):583-598. PubMed ID: 30290707
[TBL] [Abstract][Full Text] [Related]
6. Loss of TDP-43 mediates severe neurotoxicity by suppressing PJA1 gene transcription in the monkey brain.
Zhu L; Deng F; Bai D; Hou J; Jia Q; Zhang C; Ou K; Li S; Li XJ; Yin P
Cell Mol Life Sci; 2024 Jan; 81(1):16. PubMed ID: 38194085
[TBL] [Abstract][Full Text] [Related]
7. TTR (transthyretin) leads the autophagy disaster relief team against TARDBP/TDP-43 proteinopathy.
Chu YP; Ho PC; Tsai KJ
Autophagy; 2023 Aug; 19(8):2403-2405. PubMed ID: 36633448
[TBL] [Abstract][Full Text] [Related]
8. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution.
De Marco G; Lomartire A; Calvo A; Risso A; De Luca E; Mostert M; Mandrioli J; Caponnetto C; Borghero G; Manera U; Canosa A; Moglia C; Restagno G; Fini N; Tarella C; Giordana MT; Rinaudo MT; Chiò A
Neuropathol Appl Neurobiol; 2017 Feb; 43(2):133-153. PubMed ID: 27178390
[TBL] [Abstract][Full Text] [Related]
9. TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.
Van Deerlin VM; Leverenz JB; Bekris LM; Bird TD; Yuan W; Elman LB; Clay D; Wood EM; Chen-Plotkin AS; Martinez-Lage M; Steinbart E; McCluskey L; Grossman M; Neumann M; Wu IL; Yang WS; Kalb R; Galasko DR; Montine TJ; Trojanowski JQ; Lee VM; Schellenberg GD; Yu CE
Lancet Neurol; 2008 May; 7(5):409-16. PubMed ID: 18396105
[TBL] [Abstract][Full Text] [Related]
10. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
Mashiko T; Sakashita E; Kasashima K; Tominaga K; Kuroiwa K; Nozaki Y; Matsuura T; Hamamoto T; Endo H
J Biol Chem; 2016 Jul; 291(29):14996-5007. PubMed ID: 27226551
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Kim HC; Zhang Y; King PH; Lu L
J Neurochem; 2023 Mar; 164(5):643-657. PubMed ID: 36527420
[TBL] [Abstract][Full Text] [Related]
12. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains.
Yin P; Guo X; Yang W; Yan S; Yang S; Zhao T; Sun Q; Liu Y; Li S; Li XJ
Acta Neuropathol; 2019 Jun; 137(6):919-937. PubMed ID: 30810811
[TBL] [Abstract][Full Text] [Related]
13. p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death.
Foster AD; Flynn LL; Cluning C; Cheng F; Davidson JM; Lee A; Polain N; Mejzini R; Farrawell N; Yerbury JJ; Layfield R; Akkari PA; Rea SL
Sci Rep; 2021 Jun; 11(1):11474. PubMed ID: 34075102
[TBL] [Abstract][Full Text] [Related]
14. The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Janssens J; Kleinberger G; Wils H; Van Broeckhoven C
Biochem Soc Trans; 2011 Aug; 39(4):954-9. PubMed ID: 21787329
[TBL] [Abstract][Full Text] [Related]
15. Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Hadano S; Mitsui S; Pan L; Otomo A; Kubo M; Sato K; Ono S; Onodera W; Abe K; Chen X; Koike M; Uchiyama Y; Aoki M; Warabi E; Yamamoto M; Ishii T; Yanagawa T; Shang HF; Yoshii F
Hum Mol Genet; 2016 Aug; 25(15):3321-3340. PubMed ID: 27439389
[TBL] [Abstract][Full Text] [Related]
16. Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.
Torres P; Ramírez-Núñez O; Romero-Guevara R; Barés G; Granado-Serrano AB; Ayala V; Boada J; Fontdevila L; Povedano M; Sanchís D; Pamplona R; Ferrer I; Portero-Otín M
Autophagy; 2018; 14(8):1398-1403. PubMed ID: 29912613
[TBL] [Abstract][Full Text] [Related]
17. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
[TBL] [Abstract][Full Text] [Related]
18. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.
Shen WC; Li HY; Chen GC; Chern Y; Tu PH
Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089
[TBL] [Abstract][Full Text] [Related]
19. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.
Dutta K; Patel P; Rahimian R; Phaneuf D; Julien JP
Neurotherapeutics; 2017 Apr; 14(2):447-462. PubMed ID: 27928708
[TBL] [Abstract][Full Text] [Related]
20. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis.
Rutherford NJ; Zhang YJ; Baker M; Gass JM; Finch NA; Xu YF; Stewart H; Kelley BJ; Kuntz K; Crook RJ; Sreedharan J; Vance C; Sorenson E; Lippa C; Bigio EH; Geschwind DH; Knopman DS; Mitsumoto H; Petersen RC; Cashman NR; Hutton M; Shaw CE; Boylan KB; Boeve B; Graff-Radford NR; Wszolek ZK; Caselli RJ; Dickson DW; Mackenzie IR; Petrucelli L; Rademakers R
PLoS Genet; 2008 Sep; 4(9):e1000193. PubMed ID: 18802454
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
