149 related articles for article (PubMed ID: 34936867)
1. Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2.
Marek M; Ramos-Morales E; Picchi-Constante GFA; Bayer T; Norström C; Herp D; Sales-Junior PA; Guerra-Slompo EP; Hausmann K; Chakrabarti A; Shaik TB; Merz A; Troesch E; Schmidtkunz K; Goldenberg S; Pierce RJ; Mourão MM; Jung M; Schultz J; Sippl W; Zanchin NIT; Romier C
Cell Rep; 2021 Dec; 37(12):110129. PubMed ID: 34936867
[TBL] [Abstract][Full Text] [Related]
2. Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression.
Campo VA
Int J Parasitol Drugs Drug Resist; 2017 Apr; 7(1):23-33. PubMed ID: 28038431
[TBL] [Abstract][Full Text] [Related]
3. Evolutionary relationships among protein lysine deacetylases of parasites causing neglected diseases.
Scholte LLS; Mourão MM; Pais FS; Melesina J; Robaa D; Volpini AC; Sippl W; Pierce RJ; Oliveira G; Nahum LA
Infect Genet Evol; 2017 Sep; 53():175-188. PubMed ID: 28506839
[TBL] [Abstract][Full Text] [Related]
4. Metacyclogenesis defects and gene expression hallmarks of histone deacetylase 4-deficient Trypanosoma cruzi cells.
Picchi-Constante GFA; Guerra-Slompo EP; Tahira AC; Alcantara MV; Amaral MS; Ferreira AS; Batista M; Batista CM; Goldenberg S; Verjovski-Almeida S; Zanchin NIT
Sci Rep; 2021 Nov; 11(1):21671. PubMed ID: 34737385
[TBL] [Abstract][Full Text] [Related]
5. Homology modeling of parasite histone deacetylases to guide the structure-based design of selective inhibitors.
Melesina J; Robaa D; Pierce RJ; Romier C; Sippl W
J Mol Graph Model; 2015 Nov; 62():342-361. PubMed ID: 26595183
[TBL] [Abstract][Full Text] [Related]
6. Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment.
Capriles PV; Guimarães AC; Otto TD; Miranda AB; Dardenne LE; Degrave WM
BMC Genomics; 2010 Oct; 11():610. PubMed ID: 21034488
[TBL] [Abstract][Full Text] [Related]
7. Trichostatin A induces Trypanosoma cruzi histone and tubulin acetylation: effects on cell division and microtubule cytoskeleton remodelling.
de Oliveira Santos J; Zuma AA; de Luna Vitorino FN; da Cunha JPC; de Souza W; Motta MCM
Parasitology; 2019 Apr; 146(4):543-552. PubMed ID: 30421693
[TBL] [Abstract][Full Text] [Related]
8. Complexes of Trypanosoma cruzi sterol 14α-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: structural basis for pathogen selectivity.
Hargrove TY; Wawrzak Z; Alexander PW; Chaplin JH; Keenan M; Charman SA; Perez CJ; Waterman MR; Chatelain E; Lepesheva GI
J Biol Chem; 2013 Nov; 288(44):31602-15. PubMed ID: 24047900
[TBL] [Abstract][Full Text] [Related]
9. A novel receptor for platelet-activating factor and lysophosphatidylcholine in Trypanosoma cruzi.
Coelho FS; Oliveira MM; Vieira DP; Torres PHM; Moreira ICF; Martins-Duarte ES; Gonçalves IC; Cabanelas A; Pascutti PG; Fragoso SP; Lopes AH
Mol Microbiol; 2021 Sep; 116(3):890-908. PubMed ID: 34184334
[TBL] [Abstract][Full Text] [Related]
10. Comparative Analysis of the Secretome and Interactome of
Watanabe Costa R; Batista MF; Meneghelli I; Vidal RO; Nájera CA; Mendes AC; Andrade-Lima IA; da Silveira JF; Lopes LR; Ferreira LRP; Antoneli F; Bahia D
Front Immunol; 2020; 11():1774. PubMed ID: 32973747
[TBL] [Abstract][Full Text] [Related]
11. Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer.
Martinez A; Peluffo G; Petruk AA; Hugo M; Piñeyro D; Demicheli V; Moreno DM; Lima A; Batthyány C; Durán R; Robello C; Martí MA; Larrieux N; Buschiazzo A; Trujillo M; Radi R; Piacenza L
J Biol Chem; 2014 May; 289(18):12760-78. PubMed ID: 24616096
[TBL] [Abstract][Full Text] [Related]
12. Histone deacetylases in Trypanosoma brucei: two are essential and another is required for normal cell cycle progression.
Ingram AK; Horn D
Mol Microbiol; 2002 Jul; 45(1):89-97. PubMed ID: 12100550
[TBL] [Abstract][Full Text] [Related]
13. Identification of Inhibitors to
Matutino Bastos T; Botelho Pereira Soares M; Haddad Franco C; Alcântara L; Antonini L; Sabatino M; Mautone N; Holanda Freitas-Junior L; Moraes CB; Ragno R; Rotili D; Schenkman S; Mai A; Silvio Moretti N
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32455951
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
Chen YT; Brinen LS; Kerr ID; Hansell E; Doyle PS; McKerrow JH; Roush WR
PLoS Negl Trop Dis; 2010 Sep; 4(9):. PubMed ID: 20856868
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite.
Vilchez Larrea SC; Haikarainen T; Narwal M; Schlesinger M; Venkannagari H; Flawiá MM; Villamil SH; Lehtiö L
PLoS One; 2012; 7(9):e46063. PubMed ID: 23049934
[TBL] [Abstract][Full Text] [Related]
16. Biophysical and Biochemical Comparison of Extracellular Vesicles Produced by Infective and Non-Infective Stages of
Retana Moreira L; Prescilla-Ledezma A; Cornet-Gomez A; Linares F; Jódar-Reyes AB; Fernandez J; Ibarrola Vannucci AK; De Pablos LM; Osuna A
Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34068436
[TBL] [Abstract][Full Text] [Related]
17. Extensive Translational Regulation through the Proliferative Transition of Trypanosoma cruzi Revealed by Multi-Omics.
Chávez S; Urbaniak MD; Benz C; Smircich P; Garat B; Sotelo-Silveira JR; Duhagon MA
mSphere; 2021 Oct; 6(5):e0036621. PubMed ID: 34468164
[TBL] [Abstract][Full Text] [Related]
18. Repertoire, genealogy and genomic organization of cruzipain and homologous genes in Trypanosoma cruzi, T. cruzi-like and other trypanosome species.
Lima L; Ortiz PA; da Silva FM; Alves JM; Serrano MG; Cortez AP; Alfieri SC; Buck GA; Teixeira MM
PLoS One; 2012; 7(6):e38385. PubMed ID: 22685565
[TBL] [Abstract][Full Text] [Related]
19. Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.
Freymann DM; Wenck MA; Engel JC; Feng J; Focia PJ; Eakin AE; Craig SP
Chem Biol; 2000 Dec; 7(12):957-68. PubMed ID: 11137818
[TBL] [Abstract][Full Text] [Related]
20. Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.
Gaspar L; Coron RP; KongThoo Lin P; Costa DM; Perez-Cabezas B; Tavares J; Roura-Ferrer M; Ramos I; Ronin C; Major LL; Ciesielski F; Pemberton IK; MacDougall J; Ciapetti P; Smith TK; Cordeiro-da-Silva A
PLoS Negl Trop Dis; 2018 Jan; 12(1):e0006180. PubMed ID: 29357372
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]