BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 34942400)

  • 1. Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment.
    Reiner BC; Crist RC; Borner T; Doyle RP; Hayes MR; De Jonghe BC
    Mol Metab; 2022 Feb; 56():101422. PubMed ID: 34942400
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS.
    Tsai VW; Zhang HP; Manandhar R; Schofield P; Christ D; Lee-Ng KKM; Lebhar H; Marquis CP; Husaini Y; Brown DA; Breit SN
    Int J Obes (Lond); 2019 Dec; 43(12):2370-2380. PubMed ID: 31152154
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice.
    Frikke-Schmidt H; Hultman K; Galaske JW; Jørgensen SB; Myers MG; Seeley RJ
    Mol Metab; 2019 Mar; 21():13-21. PubMed ID: 30685336
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
    Emmerson PJ; Wang F; Du Y; Liu Q; Pickard RT; Gonciarz MD; Coskun T; Hamang MJ; Sindelar DK; Ballman KK; Foltz LA; Muppidi A; Alsina-Fernandez J; Barnard GC; Tang JX; Liu X; Mao X; Siegel R; Sloan JH; Mitchell PJ; Zhang BB; Gimeno RE; Shan B; Wu X
    Nat Med; 2017 Oct; 23(10):1215-1219. PubMed ID: 28846098
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
    Mullican SE; Lin-Schmidt X; Chin CN; Chavez JA; Furman JL; Armstrong AA; Beck SC; South VJ; Dinh TQ; Cash-Mason TD; Cavanaugh CR; Nelson S; Huang C; Hunter MJ; Rangwala SM
    Nat Med; 2017 Oct; 23(10):1150-1157. PubMed ID: 28846097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling.
    Worth AA; Shoop R; Tye K; Feetham CH; D'Agostino G; Dodd GT; Reimann F; Gribble FM; Beebe EC; Dunbar JD; Alexander-Chacko JT; Sindelar DK; Coskun T; Emmerson PJ; Luckman SM
    Elife; 2020 Jul; 9():. PubMed ID: 32723474
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
    Hsu JY; Crawley S; Chen M; Ayupova DA; Lindhout DA; Higbee J; Kutach A; Joo W; Gao Z; Fu D; To C; Mondal K; Li B; Kekatpure A; Wang M; Laird T; Horner G; Chan J; McEntee M; Lopez M; Lakshminarasimhan D; White A; Wang SP; Yao J; Yie J; Matern H; Solloway M; Haldankar R; Parsons T; Tang J; Shen WD; Alice Chen Y; Tian H; Allan BB
    Nature; 2017 Oct; 550(7675):255-259. PubMed ID: 28953886
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.
    Dowsett GKC; Lam BYH; Tadross JA; Cimino I; Rimmington D; Coll AP; Polex-Wolf J; Knudsen LB; Pyke C; Yeo GSH
    Mol Metab; 2021 Nov; 53():101240. PubMed ID: 33962048
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight.
    Zhang SY; Bruce K; Danaei Z; Li RJW; Barros DR; Kuah R; Lim YM; Mariani LH; Cherney DZ; Chiu JFM; Reich HN; Lam TKT
    Cell Metab; 2023 May; 35(5):875-886.e5. PubMed ID: 37060902
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
    Breit SN; Brown DA; Tsai VW
    Annu Rev Physiol; 2021 Feb; 83():127-151. PubMed ID: 33228454
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets.
    Rochette L; Zeller M; Cottin Y; Vergely C
    Trends Endocrinol Metab; 2020 Dec; 31(12):939-951. PubMed ID: 33172749
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
    Yang L; Chang CC; Sun Z; Madsen D; Zhu H; Padkjær SB; Wu X; Huang T; Hultman K; Paulsen SJ; Wang J; Bugge A; Frantzen JB; Nørgaard P; Jeppesen JF; Yang Z; Secher A; Chen H; Li X; John LM; Shan B; He Z; Gao X; Su J; Hansen KT; Yang W; Jørgensen SB
    Nat Med; 2017 Oct; 23(10):1158-1166. PubMed ID: 28846099
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
    Breit SN; Manandhar R; Zhang HP; Lee-Ng M; Brown DA; Tsai VW
    Cell Metab; 2023 Aug; 35(8):1341-1355.e3. PubMed ID: 37433299
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GFRAL Is Widely Distributed in the Brain and Peripheral Tissues of Mice.
    Fichtner K; Kalwa H; Lin MM; Gong Y; Müglitz A; Kluge M; Krügel U
    Nutrients; 2024 Mar; 16(5):. PubMed ID: 38474863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Obesity and Cachexia: Identification of the GFRAL Receptor-MIC-1/GDF15 Pathway.
    Breit SN; Tsai VW; Brown DA
    Trends Mol Med; 2017 Dec; 23(12):1065-1067. PubMed ID: 29129392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract.
    Tsai VW; Manandhar R; Jørgensen SB; Lee-Ng KK; Zhang HP; Marquis CP; Jiang L; Husaini Y; Lin S; Sainsbury A; Sawchenko PE; Brown DA; Breit SN
    PLoS One; 2014; 9(6):e100370. PubMed ID: 24971956
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.
    Suriben R; Chen M; Higbee J; Oeffinger J; Ventura R; Li B; Mondal K; Gao Z; Ayupova D; Taskar P; Li D; Starck SR; Chen HH; McEntee M; Katewa SD; Phung V; Wang M; Kekatpure A; Lakshminarasimhan D; White A; Olland A; Haldankar R; Solloway MJ; Hsu JY; Wang Y; Tang J; Lindhout DA; Allan BB
    Nat Med; 2020 Aug; 26(8):1264-1270. PubMed ID: 32661391
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases.
    Tsai VWW; Husaini Y; Sainsbury A; Brown DA; Breit SN
    Cell Metab; 2018 Sep; 28(3):353-368. PubMed ID: 30184485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GDF15: A Hormone Conveying Somatic Distress to the Brain.
    Lockhart SM; Saudek V; O'Rahilly S
    Endocr Rev; 2020 Aug; 41(4):. PubMed ID: 32310257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region.
    Maolood N; Meister B
    J Chem Neuroanat; 2009 May; 37(3):182-95. PubMed ID: 19146948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.