BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

359 related articles for article (PubMed ID: 34943834)

  • 21. Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model.
    Bosnakovski D; Chan SSK; Recht OO; Hartweck LM; Gustafson CJ; Athman LL; Lowe DA; Kyba M
    Nat Commun; 2017 Sep; 8(1):550. PubMed ID: 28916757
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics.
    Chen JC; King OD; Zhang Y; Clayton NP; Spencer C; Wentworth BM; Emerson CP; Wagner KR
    Mol Ther; 2016 Aug; 24(8):1405-11. PubMed ID: 27378237
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4.
    Homma S; Beermann ML; Yu B; Boyce FM; Miller JB
    Skelet Muscle; 2016 Dec; 6(1):42. PubMed ID: 27906075
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Direct interplay between two candidate genes in FSHD muscular dystrophy.
    Ferri G; Huichalaf CH; Caccia R; Gabellini D
    Hum Mol Genet; 2015 Mar; 24(5):1256-66. PubMed ID: 25326393
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy.
    Jagannathan S; Ogata Y; Gafken PR; Tapscott SJ; Bradley RK
    Elife; 2019 Jan; 8():. PubMed ID: 30644821
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene.
    Snider L; Geng LN; Lemmers RJ; Kyba M; Ware CB; Nelson AM; Tawil R; Filippova GN; van der Maarel SM; Tapscott SJ; Miller DG
    PLoS Genet; 2010 Oct; 6(10):e1001181. PubMed ID: 21060811
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target.
    Heher P; Ganassi M; Weidinger A; Engquist EN; Pruller J; Nguyen TH; Tassin A; Declèves AE; Mamchaoui K; Banerji CRS; Grillari J; Kozlov AV; Zammit PS
    Redox Biol; 2022 May; 51():102251. PubMed ID: 35248827
    [TBL] [Abstract][Full Text] [Related]  

  • 28. PAX7 target gene repression is a superior FSHD biomarker than DUX4 target gene activation, associating with pathological severity and identifying FSHD at the single-cell level.
    Banerji CRS; Zammit PS
    Hum Mol Genet; 2019 Jul; 28(13):2224-2236. PubMed ID: 31067297
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression.
    Resnick R; Wong CJ; Hamm DC; Bennett SR; Skene PJ; Hake SB; Henikoff S; van der Maarel SM; Tapscott SJ
    Cell Rep; 2019 Nov; 29(7):1812-1820.e5. PubMed ID: 31722199
    [TBL] [Abstract][Full Text] [Related]  

  • 30. An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy.
    Cowley MV; Pruller J; Ganassi M; Zammit PS; Banerji CRS
    Elife; 2023 May; 12():. PubMed ID: 37184373
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD.
    Nip Y; Bennett SR; Smith AA; Jones TI; Jones PL; Tapscott SJ
    Hum Mol Genet; 2023 May; 32(11):1864-1874. PubMed ID: 36728804
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A patient-derived iPSC model revealed oxidative stress increases facioscapulohumeral muscular dystrophy-causative DUX4.
    Sasaki-Honda M; Jonouchi T; Arai M; Hotta A; Mitsuhashi S; Nishino I; Matsuda R; Sakurai H
    Hum Mol Genet; 2018 Dec; 27(23):4024-4035. PubMed ID: 30107443
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The Genetics and Epigenetics of Facioscapulohumeral Muscular Dystrophy.
    Himeda CL; Jones PL
    Annu Rev Genomics Hum Genet; 2019 Aug; 20():265-291. PubMed ID: 31018108
    [TBL] [Abstract][Full Text] [Related]  

  • 34. WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy.
    Mocciaro E; Giambruno R; Micheloni S; Cernilogar FM; Andolfo A; Consonni C; Pannese M; Ferri G; Runfola V; Schotta G; Gabellini D
    Nucleic Acids Res; 2023 Jun; 51(10):5144-5161. PubMed ID: 37021550
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice.
    Bosnakovski D; Shams AS; Yuan C; da Silva MT; Ener ET; Baumann CW; Lindsay AJ; Verma M; Asakura A; Lowe DA; Kyba M
    J Clin Invest; 2020 May; 130(5):2465-2477. PubMed ID: 32250341
    [TBL] [Abstract][Full Text] [Related]  

  • 36. β-Catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy.
    Banerji CR; Knopp P; Moyle LA; Severini S; Orrell RW; Teschendorff AE; Zammit PS
    J R Soc Interface; 2015 Jan; 12(102):20140797. PubMed ID: 25551153
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A Targeted Approach for Evaluating DUX4-Regulated Proteins as Potential Serum Biomarkers for Facioscapulohumeral Muscular Dystrophy Using Immunoassay Proteomics.
    Campbell AE; Arjomand J; King OD; Tawil R; Jagannathan S
    J Neuromuscul Dis; 2023; 10(6):1031-1040. PubMed ID: 37899061
    [TBL] [Abstract][Full Text] [Related]  

  • 38. p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.
    Bosnakovski D; Gearhart MD; Toso EA; Recht OO; Cucak A; Jain AK; Barton MC; Kyba M
    Dis Model Mech; 2017 Oct; 10(10):1211-1216. PubMed ID: 28754837
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Deciphering transcription dysregulation in FSH muscular dystrophy.
    Ehrlich M; Lacey M
    J Hum Genet; 2012 Aug; 57(8):477-84. PubMed ID: 22718021
    [TBL] [Abstract][Full Text] [Related]  

  • 40. DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients.
    Dmitriev P; Bou Saada Y; Dib C; Ansseau E; Barat A; Hamade A; Dessen P; Robert T; Lazar V; Louzada RAN; Dupuy C; Zakharova V; Carnac G; Lipinski M; Vassetzky YS
    Free Radic Biol Med; 2016 Oct; 99():244-258. PubMed ID: 27519269
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.