BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 34951654)

  • 1. Activation of neutral sphingomyelinase 2 through hyperglycemia contributes to endothelial apoptosis via vesicle-bound intercellular transfer of ceramides.
    Zietzer A; Jahnel AL; Bulic M; Gutbrod K; Düsing P; Hosen MR; Dörmann P; Werner N; Nickenig G; Jansen F
    Cell Mol Life Sci; 2021 Dec; 79(1):48. PubMed ID: 34951654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Platelet extracellular vesicles mediate transfusion-related acute lung injury by imbalancing the sphingolipid rheostat.
    McVey MJ; Weidenfeld S; Maishan M; Spring C; Kim M; Tabuchi A; Srbely V; Takabe-French A; Simmons S; Arenz C; Semple JW; Kuebler WM
    Blood; 2021 Feb; 137(5):690-701. PubMed ID: 33232973
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo.
    Risner ML; Ribeiro M; McGrady NR; Kagitapalli BS; Chamling X; Zack DJ; Calkins DJ
    Cell Commun Signal; 2023 Oct; 21(1):305. PubMed ID: 37904133
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
    Hitomi K; Okada R; Loo TM; Miyata K; Nakamura AJ; Takahashi A
    Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32466233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).
    Wang G; Dinkins M; He Q; Zhu G; Poirier C; Campbell A; Mayer-Proschel M; Bieberich E
    J Biol Chem; 2012 Jun; 287(25):21384-95. PubMed ID: 22532571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function.
    Kong X; Patel NA; Chalfant CE; Cooper DR
    Cell Commun Signal; 2023 Aug; 21(1):221. PubMed ID: 37620957
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Large extracellular vesicles do not mitigate the harmful effect of hyperglycemia on endothelial cell mobility.
    Drożdż A; Kołodziej T; Wróbel S; Misztal K; Targosz-Korecka M; Drab M; Jach R; Rząca C; Surman M; Przybyło M; Rajfur Z; Stępień EŁ
    Eur J Cell Biol; 2022; 101(4):151266. PubMed ID: 35952497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis.
    Perdomo L; Vidal-Gómez X; Soleti R; Vergori L; Duluc L; Chwastyniak M; Bisserier M; Le Lay S; Villard A; Simard G; Meilhac O; Lezoualc'h F; Khantalin I; Veerapen R; Dubois S; Boursier J; Henni S; Gagnadoux F; Pinet F; Andriantsitohaina R; Martínez MC;
    Circ Res; 2020 Aug; 127(6):747-760. PubMed ID: 32539601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis.
    Niaudet C; Bonnaud S; Guillonneau M; Gouard S; Gaugler MH; Dutoit S; Ripoche N; Dubois N; Trichet V; Corre I; Paris F
    Cell Signal; 2017 May; 33():10-21. PubMed ID: 28179144
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extracellular Vesicle Subtypes Released From Activated or Apoptotic T-Lymphocytes Carry a Specific and Stimulus-Dependent Protein Cargo.
    Tucher C; Bode K; Schiller P; Claßen L; Birr C; Souto-Carneiro MM; Blank N; Lorenz HM; Schiller M
    Front Immunol; 2018; 9():534. PubMed ID: 29599781
    [TBL] [Abstract][Full Text] [Related]  

  • 11. nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe
    Lallemand T; Rouahi M; Swiader A; Grazide MH; Geoffre N; Alayrac P; Recazens E; Coste A; Salvayre R; Nègre-Salvayre A; Augé N
    Arterioscler Thromb Vasc Biol; 2018 Jul; 38(7):1479-1492. PubMed ID: 29794115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
    Lei X; Zhang S; Bohrer A; Bao S; Song H; Ramanadham S
    Biochemistry; 2007 Sep; 46(35):10170-85. PubMed ID: 17685585
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
    Mondal S; Mandal C; Sangwan R; Chandra S; Mandal C
    Mol Cancer; 2010 Sep; 9():239. PubMed ID: 20836852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation.
    Shakor AB; Atia M; Ismail IA; Alshehri A; El-Refaey H; Kwiatkowska K; Sobota A
    Biochim Biophys Acta; 2014 Dec; 1841(12):1672-82. PubMed ID: 25240837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.
    Medler TR; Petrusca DN; Lee PJ; Hubbard WC; Berdyshev EV; Skirball J; Kamocki K; Schuchman E; Tuder RM; Petrache I
    Am J Respir Cell Mol Biol; 2008 Jun; 38(6):639-46. PubMed ID: 18192502
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction.
    Meyers-Needham M; Lewis JA; Gencer S; Sentelle RD; Saddoughi SA; Clarke CJ; Hannun YA; Norell H; da Palma TM; Nishimura M; Kraveka JM; Khavandgar Z; Murshed M; Cevik MO; Ogretmen B
    Mol Cancer Ther; 2012 May; 11(5):1092-102. PubMed ID: 22452947
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation.
    Sánchez AM; Malagarie-Cazenave S; Olea N; Vara D; Chiloeches A; Díaz-Laviada I
    Apoptosis; 2007 Nov; 12(11):2013-24. PubMed ID: 17828457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium.
    Chung S; Vu S; Filosto S; Goldkorn T
    Am J Respir Cell Mol Biol; 2015 Jun; 52(6):738-48. PubMed ID: 25347576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondria-containing extracellular vesicles (EV) reduce mouse brain infarct sizes and EV/HSP27 protect ischemic brain endothelial cultures.
    Dave KM; Stolz DB; Venna VR; Quaicoe VA; Maniskas ME; Reynolds MJ; Babidhan R; Dobbins DX; Farinelli MN; Sullivan A; Bhatia TN; Yankello H; Reddy R; Bae Y; Leak RK; Shiva SS; McCullough LD; Manickam DS
    J Control Release; 2023 Feb; 354():368-393. PubMed ID: 36642252
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactive nitrogen and oxygen species activate different sphingomyelinases to induce apoptosis in airway epithelial cells.
    Castillo SS; Levy M; Thaikoottathil JV; Goldkorn T
    Exp Cell Res; 2007 Jul; 313(12):2680-6. PubMed ID: 17498692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.