144 related articles for article (PubMed ID: 34952432)
1. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1.
Mathieu C; Chamayou Q; Hyen Luong TT; Naud D; Mahuteau-Betzer F; Alami M; Fattal E; Messaoudi S; Vergnaud-Gauduchon J
Eur J Med Chem; 2022 Feb; 229():114052. PubMed ID: 34952432
[TBL] [Abstract][Full Text] [Related]
2. Mitochondrial-targeted Hsp90 C-terminal inhibitors manifest anti-proliferative activity.
Zhang Z; Banerjee M; Davis RE; Blagg BSJ
Bioorg Med Chem Lett; 2019 Nov; 29(22):126676. PubMed ID: 31591016
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors.
Audisio D; Methy-Gonnot D; Radanyi C; Renoir JM; Denis S; Sauvage F; Vergnaud-Gauduchon J; Brion JD; Messaoudi S; Alami M
Eur J Med Chem; 2014 Aug; 83():498-507. PubMed ID: 24992077
[TBL] [Abstract][Full Text] [Related]
4. Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery.
Audisio D; Messaoudi S; Cegielkowski L; Peyrat JF; Brion JD; Methy-Gonnot D; Radanyi C; Renoir JM; Alami M
ChemMedChem; 2011 May; 6(5):804-15. PubMed ID: 21374821
[TBL] [Abstract][Full Text] [Related]
5. Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.
Lee C; Park HK; Jeong H; Lim J; Lee AJ; Cheon KY; Kim CS; Thomas AP; Bae B; Kim ND; Kim SH; Suh PG; Ryu JH; Kang BH
J Am Chem Soc; 2015 Apr; 137(13):4358-67. PubMed ID: 25785725
[TBL] [Abstract][Full Text] [Related]
6. Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug.
Hu S; Ferraro M; Thomas AP; Chung JM; Yoon NG; Seol JH; Kim S; Kim HU; An MY; Ok H; Jung HS; Ryu JH; Colombo G; Kang BH
J Med Chem; 2020 Mar; 63(6):2930-2940. PubMed ID: 32068404
[TBL] [Abstract][Full Text] [Related]
7. Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1.
Sanchez-Martin C; Menon D; Moroni E; Ferraro M; Masgras I; Elsey J; Arbiser JL; Colombo G; Rasola A
Antioxid Redox Signal; 2021 Mar; 34(7):505-516. PubMed ID: 32438819
[No Abstract] [Full Text] [Related]
8. New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting.
Rondanin R; Lettini G; Oliva P; Baruchello R; Costantini C; Trapella C; Simoni D; Bernardi T; Sisinni L; Pietrafesa M; Ponterini G; Costi MP; Vignudelli T; Luciani R; Matassa DS; Esposito F; Landriscina M
Bioorg Med Chem Lett; 2018 Jul; 28(13):2289-2293. PubMed ID: 29807796
[TBL] [Abstract][Full Text] [Related]
9. Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells.
Sauvage F; Franzè S; Bruneau A; Alami M; Denis S; Nicolas V; Lesieur S; Legrand FX; Barratt G; Messaoudi S; Vergnaud-Gauduchon J
Int J Pharm; 2016 Feb; 499(1-2):101-109. PubMed ID: 26721724
[TBL] [Abstract][Full Text] [Related]
10. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
El-Shafey HW; Gomaa RM; El-Messery SM; Goda FE
Bioorg Med Chem Lett; 2020 Aug; 30(15):127281. PubMed ID: 32527460
[TBL] [Abstract][Full Text] [Related]
11. Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo.
Liu YM; Tu HJ; Wu CH; Lai MJ; Yu SC; Chao MW; Wu YW; Teng CM; Pan SL; Liou JP
Eur J Med Chem; 2021 Jul; 219():113428. PubMed ID: 33934008
[TBL] [Abstract][Full Text] [Related]
12. Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
Park HK; Jeong H; Ko E; Lee G; Lee JE; Lee SK; Lee AJ; Im JY; Hu S; Kim SH; Lee JH; Lee C; Kang S; Kang BH
J Med Chem; 2017 Sep; 60(17):7569-7578. PubMed ID: 28816449
[TBL] [Abstract][Full Text] [Related]
13. Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.
Kim H; Yang J; Kim MJ; Choi S; Chung JR; Kim JM; Yoo YH; Chung J; Koh H
J Biol Chem; 2016 Jan; 291(4):1841-1853. PubMed ID: 26631731
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, antimicrobial activity and cytotoxicity of triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl nucleoside analogues.
Yu Strobykina I; Voloshina AD; Andreeva OV; Sapunova AS; Lyubina AP; Amerhanova SK; Belenok MG; Saifina LF; Semenov VE; Kataev VE
Bioorg Chem; 2021 Nov; 116():105328. PubMed ID: 34500307
[TBL] [Abstract][Full Text] [Related]
15. 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.
Nepali K; Kumar S; Huang HL; Kuo FC; Lee CH; Kuo CC; Yeh TK; Li YH; Chang JY; Liou JP; Lee HY
Org Biomol Chem; 2016 Jan; 14(2):716-723. PubMed ID: 26694589
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, Anticancer, and Antibacterial Activity of Betulinic and Betulonic Acid C-28-Triphenylphosphonium Conjugates with Variable Alkyl Linker Length.
Tsepaeva OV; Nemtarev AV; Salikhova TI; Abdullin TI; Grigor Eva LR; Khozyainova SA; Mironov VF
Anticancer Agents Med Chem; 2020; 20(3):286-300. PubMed ID: 31660842
[TBL] [Abstract][Full Text] [Related]
17. Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site.
Yoon NG; Lee H; Kim SY; Hu S; Kim D; Yang S; Hong KB; Lee JH; Kang S; Kim BG; Myung K; Lee C; Kang BH
J Am Chem Soc; 2021 Dec; 143(47):19684-19696. PubMed ID: 34758612
[TBL] [Abstract][Full Text] [Related]
18. Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1.
Sanchez-Martin C; Moroni E; Ferraro M; Laquatra C; Cannino G; Masgras I; Negro A; Quadrelli P; Rasola A; Colombo G
Cell Rep; 2020 Apr; 31(3):107531. PubMed ID: 32320652
[TBL] [Abstract][Full Text] [Related]
19. Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level.
Yoo SH; Kim HY; Rho JH; Jeong SY; Yun J; Yun I; Park HT; Yoo YH
Int J Oncol; 2015 Nov; 47(5):1783-92. PubMed ID: 26351876
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and biological evaluation of a series of resorcinol-based N-benzyl benzamide derivatives as potent Hsp90 inhibitors.
Park SY; Oh YJ; Lho Y; Jeong JH; Liu KH; Song J; Kim SH; Ha E; Seo YH
Eur J Med Chem; 2018 Jan; 143():390-401. PubMed ID: 29202402
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
