These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 34954237)

  • 1. Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4
    Hwang S; Pan C; Garcia B; Davidson AR; Moraes TF; Maxwell KL
    J Mol Biol; 2022 Mar; 434(5):167420. PubMed ID: 34954237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins.
    Lee J; Mir A; Edraki A; Garcia B; Amrani N; Lou HE; Gainetdinov I; Pawluk A; Ibraheim R; Gao XD; Liu P; Davidson AR; Maxwell KL; Sontheimer EJ
    mBio; 2018 Dec; 9(6):. PubMed ID: 30514786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AcrIIA5 Inhibits a Broad Range of Cas9 Orthologs by Preventing DNA Target Cleavage.
    Song G; Zhang F; Zhang X; Gao X; Zhu X; Fan D; Tian Y
    Cell Rep; 2019 Nov; 29(9):2579-2589.e4. PubMed ID: 31775029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural insights into DNA cleavage activation of CRISPR-Cas9 system.
    Huai C; Li G; Yao R; Zhang Y; Cao M; Kong L; Jia C; Yuan H; Chen H; Lu D; Huang Q
    Nat Commun; 2017 Nov; 8(1):1375. PubMed ID: 29123204
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
    Thavalingam A; Cheng Z; Garcia B; Huang X; Shah M; Sun W; Wang M; Harrington L; Hwang S; Hidalgo-Reyes Y; Sontheimer EJ; Doudna J; Davidson AR; Moraes TF; Wang Y; Maxwell KL
    Nat Commun; 2019 Jun; 10(1):2806. PubMed ID: 31243272
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AcrIIA28 is a metalloprotein that specifically inhibits targeted-DNA loading to SpyCas9 by binding to the REC3 domain.
    Kim GE; Park HH
    Nucleic Acids Res; 2024 Jun; 52(11):6459-6471. PubMed ID: 38726868
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4.
    Li X; Liao F; Gao J; Song G; Zhang C; Ji N; Wang X; Wen J; He J; Wei Y; Zhang H; Li Z; Yu G; Yin H
    Nucleic Acids Res; 2023 Sep; 51(17):9442-9451. PubMed ID: 37587688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of inhibition of CRISPR-Cas9 by anti-CRISPR protein AcrIIC1.
    Zhu Y; Yin S; Li Z
    Biochem Biophys Res Commun; 2023 Apr; 654():34-39. PubMed ID: 36878037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Broad-Spectrum Inhibitor of CRISPR-Cas9.
    Harrington LB; Doxzen KW; Ma E; Liu JJ; Knott GJ; Edraki A; Garcia B; Amrani N; Chen JS; Cofsky JC; Kranzusch PJ; Sontheimer EJ; Davidson AR; Maxwell KL; Doudna JA
    Cell; 2017 Sep; 170(6):1224-1233.e15. PubMed ID: 28844692
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intrinsic disorder is essential for Cas9 inhibition of anti-CRISPR AcrIIA5.
    An SY; Ka D; Kim I; Kim EH; Kim NK; Bae E; Suh JY
    Nucleic Acids Res; 2020 Jul; 48(13):7584-7594. PubMed ID: 32544231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis of Staphylococcus aureus Cas9 inhibition by AcrIIA14.
    Liu H; Zhu Y; Lu Z; Huang Z
    Nucleic Acids Res; 2021 Jun; 49(11):6587-6595. PubMed ID: 34107040
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Real-time observation of flexible domain movements in CRISPR-Cas9.
    Osuka S; Isomura K; Kajimoto S; Komori T; Nishimasu H; Shima T; Nureki O; Uemura S
    EMBO J; 2018 May; 37(10):. PubMed ID: 29650679
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Critical Anti-CRISPR Locus Repression by a Bi-functional Cas9 Inhibitor.
    Osuna BA; Karambelkar S; Mahendra C; Sarbach A; Johnson MC; Kilcher S; Bondy-Denomy J
    Cell Host Microbe; 2020 Jul; 28(1):23-30.e5. PubMed ID: 32325051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
    Sun W; Cheng Z; Wang J; Yang J; Li X; Wang J; Chen M; Yang X; Sheng G; Lou J; Wang Y
    Proc Natl Acad Sci U S A; 2023 Aug; 120(31):e2303675120. PubMed ID: 37494395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes.
    Osuna BA; Karambelkar S; Mahendra C; Christie KA; Garcia B; Davidson AR; Kleinstiver BP; Kilcher S; Bondy-Denomy J
    Cell Host Microbe; 2020 Jul; 28(1):31-40.e9. PubMed ID: 32325050
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.
    Fuchsbauer O; Swuec P; Zimberger C; Amigues B; Levesque S; Agudelo D; Duringer A; Chaves-Sanjuan A; Spinelli S; Rousseau GM; Velimirovic M; Bolognesi M; Roussel A; Cambillau C; Moineau S; Doyon Y; Goulet A
    Mol Cell; 2019 Dec; 76(6):922-937.e7. PubMed ID: 31604602
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Key role of the REC lobe during CRISPR-Cas9 activation by 'sensing', 'regulating', and 'locking' the catalytic HNH domain.
    Palermo G; Chen JS; Ricci CG; Rivalta I; Jinek M; Batista VS; Doudna JA; McCammon JA
    Q Rev Biophys; 2018; 51():. PubMed ID: 30555184
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-CRISPR AcrIIC5 is a dsDNA mimic that inhibits type II-C Cas9 effectors by blocking PAM recognition.
    Sun W; Zhao X; Wang J; Yang X; Cheng Z; Liu S; Wang J; Sheng G; Wang Y
    Nucleic Acids Res; 2023 Feb; 51(4):1984-1995. PubMed ID: 36744495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity.
    Zhang S; Sun A; Qian JM; Lin S; Xing W; Yang Y; Zhu HZ; Zhou XY; Guo YS; Liu Y; Meng Y; Jin SL; Song W; Li CP; Li Z; Jin S; Wang JH; Dong MQ; Gao C; Chen C; Bai Y; Liu JG
    Nature; 2024 Jun; 630(8016):484-492. PubMed ID: 38811729
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exploring alternative catalytic mechanisms of the Cas9 HNH domain.
    Zhao LN; Mondal D; Warshel A
    Proteins; 2020 Feb; 88(2):260-264. PubMed ID: 31390092
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.