BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 34959176)

  • 21. Novel 4-methylsulfonylphenyl derivatives as NSAIDS with preferential COX-2 inhibition.
    Amin NH; Mohammed AA; Abdellatif KR
    Future Med Chem; 2018 Jan; 10(1):53-70. PubMed ID: 29235887
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis, evaluation and docking of novel pyrazolo pyrimidines as potent p38α MAP kinase inhibitors with improved anti-inflammatory, ulcerogenic and TNF-α inhibitory properties.
    Somakala K; Tariq S; Amir M
    Bioorg Chem; 2019 Jun; 87():550-559. PubMed ID: 30928877
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity.
    Halim PA; Georgey HH; George MY; El Kerdawy AM; Said MF
    Bioorg Chem; 2021 Oct; 115():105253. PubMed ID: 34390973
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis of novel 1,2,3-triazole based benzoxazolinones: their TNF-α based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk evaluation.
    Haider S; Alam MS; Hamid H; Shafi S; Nargotra A; Mahajan P; Nazreen S; Kalle AM; Kharbanda C; Ali Y; Alam A; Panda AK
    Eur J Med Chem; 2013; 70():579-88. PubMed ID: 24211633
    [TBL] [Abstract][Full Text] [Related]  

  • 25. New methyl 5-(halomethyl)-1-aryl-1H-1,2,4-triazole-3-carboxylates as selective COX-2 inhibitors and anti-inflammatory agents: Design, synthesis, biological evaluation, and docking study.
    Li SM; Tsai SE; Chiang CY; Chung CY; Chuang TJ; Tseng CC; Jiang WP; Huang GJ; Lin CY; Yang YC; Fuh MT; Wong FF
    Bioorg Chem; 2020 Nov; 104():104333. PubMed ID: 33142408
    [TBL] [Abstract][Full Text] [Related]  

  • 26. COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core.
    Abdelall EKA; Lamie PF; Ahmed AKM; El-Nahass ES
    Bioorg Chem; 2019 May; 86():235-253. PubMed ID: 30716621
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design and Synthesis of Novel Anti-inflammatory/Anti-ulcer Hybrid Molecules with Antioxidant Activity.
    Chaudhari BB; Bali A; Balaini A
    Med Chem; 2021; 17(9):994-1006. PubMed ID: 32998679
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 1,4-Diaryl-1,2,3-triazole neolignan-celecoxib hybrids inhibit experimental arthritis induced by zymosan.
    Felipe JL; Bonfá IS; Lossavaro PKMB; Lencina JS; B Carvalho D; Candeloro L; Ferreira GIS; das Neves AR; Souza MIL; Silva-Filho SE; Baroni ACM; Toffoli-Kadri MC
    Inflammopharmacology; 2023 Dec; 31(6):3227-3241. PubMed ID: 37806984
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biological properties of aryl methyl sulfones.
    Navarro L; Rosell G; Sánchez S; Boixareu N; Pors K; Pouplana R; Campanera JM; Pujol MD
    Bioorg Med Chem; 2018 Aug; 26(14):4113-4126. PubMed ID: 29980364
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.
    Sarigol D; Uzgoren-Baran A; Tel BC; Somuncuoglu EI; Kazkayasi I; Ozadali-Sari K; Unsal-Tan O; Okay G; Ertan M; Tozkoparan B
    Bioorg Med Chem; 2015 May; 23(10):2518-28. PubMed ID: 25868745
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
    Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
    Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
    [TBL] [Abstract][Full Text] [Related]  

  • 32. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.
    Alfayomy AM; Abdel-Aziz SA; Marzouk AA; Shaykoon MSA; Narumi A; Konno H; Abou-Seri SM; Ragab FAF
    Bioorg Chem; 2021 Mar; 108():104555. PubMed ID: 33376011
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity.
    Abdel-Aziz M; Beshr EA; Abdel-Rahman IM; Ozadali K; Tan OU; Aly OM
    Eur J Med Chem; 2014 Apr; 77():155-65. PubMed ID: 24631895
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
    Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of new nicotinate derivatives as potential anti-inflammatory agents targeting COX-2 enzyme.
    El-Dash Y; Khalil NA; Ahmed EM; Hassan MSA
    Bioorg Chem; 2021 Feb; 107():104610. PubMed ID: 33454504
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors.
    Mohamed MFA; Marzouk AA; Nafady A; El-Gamal DA; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Moustafa AH
    Bioorg Chem; 2020 Dec; 105():104439. PubMed ID: 33161252
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel pyrimidine-pyridine hybrids: Synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability.
    Abdelgawad MA; Bakr RB; Azouz AA
    Bioorg Chem; 2018 Apr; 77():339-348. PubMed ID: 29421710
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis and biological evaluations of new nitric oxide-anti-inflammatory drug hybrids.
    Abdelall EKA; Abdelhamid AO; Azouz AA
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4358-4369. PubMed ID: 28844389
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
    Jiang B; Huang X; Yao H; Jiang J; Wu X; Jiang S; Wang Q; Lu T; Xu J
    Org Biomol Chem; 2014 Apr; 12(13):2114-27. PubMed ID: 24562695
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.