These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 34965283)

  • 1. Reversion mutations in phosphoprotein P of a codon-pair-deoptimized human respiratory syncytial virus confer increased transcription, immunogenicity, and genetic stability without loss of attenuation.
    Chen JW; Yang L; Santos C; Hassan SA; Collins PL; Buchholz UJ; Le Nouën C
    PLoS Pathog; 2021 Dec; 17(12):e1010191. PubMed ID: 34965283
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.
    Le Nouën C; McCarty T; Brown M; Smith ML; Lleras R; Dolan MA; Mehedi M; Yang L; Luongo C; Liang B; Munir S; DiNapoli JM; Mueller S; Wimmer E; Collins PL; Buchholz UJ
    Proc Natl Acad Sci U S A; 2017 Jan; 114(3):E386-E395. PubMed ID: 28049853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rescue of codon-pair deoptimized respiratory syncytial virus by the emergence of genomes with very large internal deletions that complemented replication.
    Le Nouën C; McCarty T; Yang L; Brown M; Wimmer E; Collins PL; Buchholz UJ
    Proc Natl Acad Sci U S A; 2021 Mar; 118(13):. PubMed ID: 33753491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters.
    Levy M; Chen JW; Kaiser JA; Park HS; Liu X; Yang L; Santos C; Buchholz UJ; Le Nouën C
    PLoS Pathog; 2024 May; 20(5):e1012198. PubMed ID: 38739647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication
    Le Nouën C; Luongo CL; Yang L; Mueller S; Wimmer E; DiNapoli JM; Collins PL; Buchholz UJ
    J Virol; 2020 Jan; 94(2):. PubMed ID: 31666376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization.
    Le Nouën C; Brock LG; Luongo C; McCarty T; Yang L; Mehedi M; Wimmer E; Mueller S; Collins PL; Buchholz UJ; DiNapoli JM
    Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13169-74. PubMed ID: 25157129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes.
    Meng J; Lee S; Hotard AL; Moore ML
    mBio; 2014 Sep; 5(5):e01704-14. PubMed ID: 25249281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding.
    Le Nouën C; Collins PL; Buchholz UJ
    Front Immunol; 2019; 10():1250. PubMed ID: 31231383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stable Attenuation of Human Respiratory Syncytial Virus for Live Vaccines by Deletion and Insertion of Amino Acids in the Hinge Region between the mRNA Capping and Methyltransferase Domains of the Large Polymerase Protein.
    Xue M; Wang R; Harder O; Chen P; Lu M; Cai H; Li A; Liang X; Jennings R; La Perle K; Niewiesk S; Peeples ME; Li J
    J Virol; 2020 Nov; 94(24):. PubMed ID: 32999025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates.
    Luongo C; Yang L; Winter CC; Spann KM; Murphy BR; Collins PL; Buchholz UJ
    Vaccine; 2009 Sep; 27(41):5667-76. PubMed ID: 19646406
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic Stability of Parainfluenza Virus 5-Vectored Human Respiratory Syncytial Virus Vaccine Candidates after
    Phan SI; Adam CM; Chen Z; Citron M; Liang X; Espeseth AS; Wang D; He B
    J Virol; 2017 Oct; 91(19):. PubMed ID: 28747497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection.
    Liang B; Munir S; Amaro-Carambot E; Surman S; Mackow N; Yang L; Buchholz UJ; Collins PL; Schaap-Nutt A
    J Virol; 2014 Apr; 88(8):4237-50. PubMed ID: 24478424
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates.
    Mueller S; Stauft CB; Kalkeri R; Koidei F; Kushnir A; Tasker S; Coleman JR
    Vaccine; 2020 Mar; 38(14):2943-2948. PubMed ID: 32107060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein.
    Alamares-Sapuay J; Kishko M; Lai C; Parrington M; Delagrave S; Herbert R; Castens A; Swerczek J; Luongo C; Yang L; Collins PL; Buchholz UJ; Zhang L
    PLoS One; 2024; 19(4):e0301773. PubMed ID: 38593167
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of the Safety and Immune Efficacy of Recombinant Human Respiratory Syncytial Virus Strain Long Live Attenuated Vaccine Candidates.
    Wang LN; Peng XL; Xu M; Zheng YB; Jiao YY; Yu JM; Fu YH; Zheng YP; Zhu WY; Dong ZJ; He JS
    Virol Sin; 2021 Aug; 36(4):706-720. PubMed ID: 33559831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human parainfluenza virus 3 vaccine candidates attenuated by codon-pair deoptimization are immunogenic and protective in hamsters.
    Afroz S; Saul S; Dai J; Surman S; Liu X; Park HS; Le Nouën C; Lingemann M; Dahal B; Coleman JR; Mueller S; Collins PL; Buchholz UJ; Munir S
    Proc Natl Acad Sci U S A; 2024 Jun; 121(25):e2316376121. PubMed ID: 38861603
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Addition of a missense mutation present in the L gene of respiratory syncytial virus (RSV) cpts530/1030 to RSV vaccine candidate cpts248/404 increases its attenuation and temperature sensitivity.
    Whitehead SS; Firestone CY; Karron RA; Crowe JE; Elkins WR; Collins PL; Murphy BR
    J Virol; 1999 Feb; 73(2):871-7. PubMed ID: 9882287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Murine Pneumonia Virus Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus from an Added Gene Is Highly Attenuated and Immunogenic in Rhesus Macaques.
    Brock LG; Liu X; Liang B; Lingemann M; Liu X; Herbert R; Hackenberg AD; Buchholz UJ; Collins PL; Munir S
    J Virol; 2018 Sep; 92(17):. PubMed ID: 29925656
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of temperature-sensitive mutations in the phosphoprotein of respiratory syncytial virus that are likely involved in its interaction with the nucleoprotein.
    Lu B; Brazas R; Ma CH; Kristoff T; Cheng X; Jin H
    J Virol; 2002 Mar; 76(6):2871-80. PubMed ID: 11861854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased genetic and phenotypic stability of a promising live-attenuated respiratory syncytial virus vaccine candidate by reverse genetics.
    Luongo C; Winter CC; Collins PL; Buchholz UJ
    J Virol; 2012 Oct; 86(19):10792-804. PubMed ID: 22837193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.