BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 34966788)

  • 1. Unraveling the Influence of K280 Acetylation on the Conformational Features of Tau Core Fragment: A Molecular Dynamics Simulation Study.
    Zou Y; Guan L
    Front Mol Biosci; 2021; 8():801577. PubMed ID: 34966788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of Aggregation Mechanism of Acetylated PHF6* and PHF6 Tau Peptides Based on Molecular Dynamics Simulations and Markov State Modeling.
    Shah SJA; Zhang Q; Guo J; Liu H; Liu H; Villà-Freixa J
    ACS Chem Neurosci; 2023 Nov; 14(21):3959-3971. PubMed ID: 37830541
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insights into the co-aggregation of Aβ and tau amyloid core peptides: Revealing potential pathological heterooligomers by simulations.
    Li X; Chen Y; Yang Z; Zhang S; Wei G; Zhang L
    Int J Biol Macromol; 2024 Jan; 254(Pt 2):127841. PubMed ID: 37924907
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Atomistic Insights into the Inhibitory Mechanism of Tyrosine Phosphorylation against the Aggregation of Human Tau Fragment PHF6.
    Zou Y; Guan L; Tan J; Qi B; Wang Y; Zhang Q; Sun Y
    J Phys Chem B; 2023 Jan; 127(1):335-345. PubMed ID: 36594671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Insights into the Differential Effects of Acetylation on the Aggregation of Tau Microtubule-Binding Repeats.
    Zou Y; Guan L; Tan J; Qi B; Sun Y; Huang F; Zhang Q
    J Chem Inf Model; 2024 Apr; 64(8):3386-3399. PubMed ID: 38489841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deciphering the Inhibitory Mechanism of Naphthoquinone-Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6.
    Zou Y; Qi B; Tan J; Guan L; Zhang Q; Sun Y; Huang F
    ACS Chem Neurosci; 2023 Sep; 14(17):3265-3277. PubMed ID: 37585669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
    Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
    ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Membrane-mediated fibrillation and toxicity of the tau hexapeptide PHF6.
    Fanni AM; Vander Zanden CM; Majewska PV; Majewski J; Chi EY
    J Biol Chem; 2019 Oct; 294(42):15304-15317. PubMed ID: 31439664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations.
    Dong X; Qi R; Qiao Q; Li X; Li F; Wan J; Zhang Q; Wei G
    Phys Chem Chem Phys; 2021 Sep; 23(36):20406-20418. PubMed ID: 34494046
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deciphering the Role of ATP on PHF6 Aggregation.
    Pal S; Roy R; Paul S
    J Phys Chem B; 2022 Jul; 126(26):4761-4775. PubMed ID: 35759245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Terminal Capping of an Amyloidogenic Tau Fragment Modulates Its Fibrillation Propensity.
    Arya S; Ganguly P; Arsiccio A; Claud SL; Trapp B; Schonfeld GE; Liu X; Lazar Cantrell K; Shea JE; Bowers MT
    J Phys Chem B; 2020 Oct; 124(40):8772-8783. PubMed ID: 32816481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mapping the configurational landscape and aggregation phase behavior of the tau protein fragment PHF6.
    Pretti E; Shell MS
    Proc Natl Acad Sci U S A; 2023 Nov; 120(48):e2309995120. PubMed ID: 37983502
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Post-translational modifications within tau paired helical filament nucleating motifs perturb microtubule interactions and oligomer formation.
    Acosta DM; Mancinelli C; Bracken C; Eliezer D
    J Biol Chem; 2022 Jan; 298(1):101442. PubMed ID: 34838590
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational Insights Into the Inhibition Mechanism of Proanthocyanidin B2 on Tau Hexapeptide (PHF6) Oligomer.
    Li Q; Xiong C; Liu H; Ge H; Yao X; Liu H
    Front Chem; 2021; 9():666043. PubMed ID: 34336783
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural transitions in tau k18 on micelle binding suggest a hierarchy in the efficacy of individual microtubule-binding repeats in filament nucleation.
    Barré P; Eliezer D
    Protein Sci; 2013 Aug; 22(8):1037-48. PubMed ID: 23740819
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6.
    Smit FX; Luiken JA; Bolhuis PG
    J Phys Chem B; 2017 Apr; 121(15):3250-3261. PubMed ID: 27776213
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.
    Ganguly P; Do TD; Larini L; LaPointe NE; Sercel AJ; Shade MF; Feinstein SC; Bowers MT; Shea JE
    J Phys Chem B; 2015 Apr; 119(13):4582-93. PubMed ID: 25775228
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of PHF6 Peptide of Tau Protein.
    Man VH; He X; Gao J; Wang J
    J Chem Theory Comput; 2021 Oct; 17(10):6458-6471. PubMed ID: 34491058
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent Tau Aggregation Inhibitor D-Peptides Selected against Tau-Repeat 2 Using Mirror Image Phage Display.
    Malhis M; Kaniyappan S; Aillaud I; Chandupatla RR; Ramirez LM; Zweckstetter M; Horn AHC; Mandelkow E; Sticht H; Funke SA
    Chembiochem; 2021 Nov; 22(21):3049-3059. PubMed ID: 34375027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tau acetylation at K280 regulates tau phosphorylation.
    Kim MS; Mun YS; Lee SE; Cho WY; Han SH; Kim DH; Yoon SY
    Int J Neurosci; 2023 Dec; 133(12):1394-1398. PubMed ID: 35603448
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.