These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 34977582)

  • 1. Biodegradable self-assembly micelles significantly enhanced the solubility, biological stability and
    Fang J; Chen Z; Song J; Li J; Han Y; Hou W; Wang W; Ruan BH
    RSC Chem Biol; 2021 Dec; 2(6):1669-1681. PubMed ID: 34977582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Self-Assembled Micellar Glutaminase Allosteric Inhibitor for Effective Therapeutic Intervention.
    Fang J; Chen Z; Li J; Li D; Wang W; Ruan BH
    Int J Nanomedicine; 2022; 17():213-225. PubMed ID: 35058693
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kidney-Type Glutaminase Inhibitor Hexylselen Selectively Kills Cancer Cells via a Three-Pronged Mechanism.
    Ruan JJ; Yu Y; Hou W; Chen Z; Fang J; Zhang J; Ni M; Li D; Lu S; Rui J; Wu R; Zhang W; Ruan BH
    ACS Pharmacol Transl Sci; 2019 Feb; 2(1):18-30. PubMed ID: 32219214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of biotinylated Hexylselen as a probe to identify KGA allosteric inhibitors by a convenient biomolecular interaction assay.
    Hou W; Fang J; Su L; Ye H; Ruan BH
    Bioorg Med Chem Lett; 2019 Sep; 29(17):2498-2502. PubMed ID: 31324513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
    Thangavelu K; Pan CQ; Karlberg T; Balaji G; Uttamchandani M; Suresh V; Schüler H; Low BC; Sivaraman J
    Proc Natl Acad Sci U S A; 2012 May; 109(20):7705-10. PubMed ID: 22538822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
    Ramachandran S; Pan CQ; Zimmermann SC; Duvall B; Tsukamoto T; Low BC; Sivaraman J
    Oncotarget; 2016 Sep; 7(36):57943-57954. PubMed ID: 27462863
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diselenide Covalent Allosteric Inhibitors of Glutaminase with Strong
    Hou W; Chen Z; Pan C; Ni M; Ruan H; Song J; Lu S; Bhasin A; Ruan BH
    ACS Med Chem Lett; 2023 Jul; 14(7):920-928. PubMed ID: 37465295
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biomolecular Interaction Assays Identified Dual Inhibitors of Glutaminase and Glutamate Dehydrogenase That Disrupt Mitochondrial Function and Prevent Growth of Cancer Cells.
    Zhu M; Fang J; Zhang J; Zhang Z; Xie J; Yu Y; Ruan JJ; Chen Z; Hou W; Yang G; Su W; Ruan BH
    Anal Chem; 2017 Feb; 89(3):1689-1696. PubMed ID: 28208301
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor targeting by pH-sensitive, biodegradable, cross-linked N-(2-hydroxypropyl) methacrylamide copolymer micelles.
    Zhou Z; Li L; Yang Y; Xu X; Huang Y
    Biomaterials; 2014 Aug; 35(24):6622-35. PubMed ID: 24814427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improved oral bioavailability and anticancer efficacy on breast cancer of paclitaxel via Novel Soluplus(®)-Solutol(®) HS15 binary mixed micelles system.
    Hou J; Sun E; Sun C; Wang J; Yang L; Jia XB; Zhang ZH
    Int J Pharm; 2016 Oct; 512(1):186-193. PubMed ID: 27567930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel 1,3,4-Selenadiazole-Containing Kidney-Type Glutaminase Inhibitors Showed Improved Cellular Uptake and Antitumor Activity.
    Chen Z; Li D; Xu N; Fang J; Yu Y; Hou W; Ruan H; Zhu P; Ma R; Lu S; Cao D; Wu R; Ni M; Zhang W; Su W; Ruan BH
    J Med Chem; 2019 Jan; 62(2):589-603. PubMed ID: 30543285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preparation and evaluation of self-assembly Soluplus
    Jiang S; Mou Y; He H; Yang D; Qin L; Zhang F; Zhang P
    Drug Dev Ind Pharm; 2019 Nov; 45(11):1788-1798. PubMed ID: 31500443
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel tellurodibenzoic acid compounds as kidney-type glutaminase (KGA) inhibitors.
    Hou W; Zhou Y; Rui J; Bai R; Bhasin AKK; Ruan BH
    Bioorg Med Chem Lett; 2019 Jul; 29(13):1673-1676. PubMed ID: 31076348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES).
    Robinson MM; McBryant SJ; Tsukamoto T; Rojas C; Ferraris DV; Hamilton SK; Hansen JC; Curthoys NP
    Biochem J; 2007 Sep; 406(3):407-14. PubMed ID: 17581113
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of Novel Kidney-Type Glutaminase Allosteric Inhibitors Targeting the Critical Lys-320 Residue.
    Song J; Pan C; Li J; Bai R; Zeng Z; Han Y; Chen Z; Hou W; Li Y; Ruan BH
    ACS Med Chem Lett; 2023 Jan; 14(1):11-17. PubMed ID: 36655131
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formulation of injectable glycyrrhizic acid-hydroxycamptothecin micelles as new generation of DNA topoisomerase I inhibitor for enhanced antitumor activity.
    Cai J; Luo S; Lv X; Deng Y; Huang H; Zhao B; Zhang Q; Li G
    Int J Pharm; 2019 Nov; 571():118693. PubMed ID: 31525442
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development and evaluation of a novel drug delivery: Soluplus
    Ding Y; Wang C; Wang Y; Xu Y; Zhao J; Gao M; Ding Y; Peng J; Li L
    Drug Dev Ind Pharm; 2018 Sep; 44(9):1409-1416. PubMed ID: 29718714
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
    Elgogary A; Xu Q; Poore B; Alt J; Zimmermann SC; Zhao L; Fu J; Chen B; Xia S; Liu Y; Neisser M; Nguyen C; Lee R; Park JK; Reyes J; Hartung T; Rojas C; Rais R; Tsukamoto T; Semenza GL; Hanes J; Slusher BS; Le A
    Proc Natl Acad Sci U S A; 2016 Sep; 113(36):E5328-36. PubMed ID: 27559084
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel polymeric micelles as enzyme-sensitive nuclear-targeted dual-functional drug delivery vehicles for enhanced 9-nitro-20(S)-camptothecin delivery and antitumor efficacy.
    Sun Y; Liang Y; Hao N; Fu X; He B; Han S; Cao J; Ma Q; Xu W; Sun Y
    Nanoscale; 2020 Mar; 12(9):5380-5396. PubMed ID: 32022069
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing the anti-colon cancer activity of quercetin by self-assembled micelles.
    Xu G; Shi H; Ren L; Gou H; Gong D; Gao X; Huang N
    Int J Nanomedicine; 2015; 10():2051-63. PubMed ID: 25844036
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.