BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

389 related articles for article (PubMed ID: 34978586)

  • 1. Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose.
    Akakpo JY; Ramachandran A; Curry SC; Rumack BH; Jaeschke H
    Arch Toxicol; 2022 Feb; 96(2):453-465. PubMed ID: 34978586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole.
    Akakpo JY; Jaeschke MW; Ramachandran A; Curry SC; Rumack BH; Jaeschke H
    Arch Toxicol; 2021 Oct; 95(10):3377-3391. PubMed ID: 34420083
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
    Link SL; Rampon G; Osmon S; Scalzo AJ; Rumack BH
    Clin Toxicol (Phila); 2022 Apr; 60(4):472-477. PubMed ID: 34709101
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning: A scoping review.
    Pourbagher-Shahri AM; Schimmel J; Shirazi FM; Nakhaee S; Mehrpour O
    Toxicol Lett; 2022 Feb; 355():47-61. PubMed ID: 34785186
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine.
    Akakpo JY; Ramachandran A; Rumack BH; Wallace DP; Jaeschke H
    Toxicology; 2023 Dec; 500():153692. PubMed ID: 38042273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase.
    Akakpo JY; Ramachandran A; Duan L; Schaich MA; Jaeschke MW; Freudenthal BD; Ding WX; Rumack BH; Jaeschke H
    Toxicol Sci; 2019 Jul; 170(1):57-68. PubMed ID: 30903181
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical outcome of massive acetaminophen overdose treated with standard-dose N-acetylcysteine.
    Downs JW; Cumpston KL; Kershner EK; Troendle MM; Rose SR; Wills BK
    Clin Toxicol (Phila); 2021 Oct; 59(10):932-936. PubMed ID: 33620007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes.
    Akakpo JY; Ramachandran A; Kandel SE; Ni HM; Kumer SC; Rumack BH; Jaeschke H
    Hum Exp Toxicol; 2018 Dec; 37(12):1310-1322. PubMed ID: 29739258
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-methylpyrazole protects against acetaminophen-induced acute kidney injury.
    Akakpo JY; Ramachandran A; Orhan H; Curry SC; Rumack BH; Jaeschke H
    Toxicol Appl Pharmacol; 2020 Dec; 409():115317. PubMed ID: 33157119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel Therapeutic Approaches Against Acetaminophen-induced Liver Injury and Acute Liver Failure.
    Jaeschke H; Akakpo JY; Umbaugh DS; Ramachandran A
    Toxicol Sci; 2020 Apr; 174(2):159-167. PubMed ID: 31926003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-acetylcysteine amide, a promising antidote for acetaminophen toxicity.
    Khayyat A; Tobwala S; Hart M; Ercal N
    Toxicol Lett; 2016 Jan; 241():133-42. PubMed ID: 26602168
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose.
    Doyon S; Klein-Schwartz W
    Acad Emerg Med; 2009 Jan; 16(1):34-9. PubMed ID: 19007345
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane.
    Etemadi Y; Akakpo JY; Ramachandran A; Jaeschke H
    J Biochem Mol Toxicol; 2023 Dec; 37(12):e23505. PubMed ID: 37598316
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel strategies for the treatment of acetaminophen hepatotoxicity.
    Akakpo JY; Ramachandran A; Jaeschke H
    Expert Opin Drug Metab Toxicol; 2020 Nov; 16(11):1039-1050. PubMed ID: 32862728
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity.
    Yang R; Miki K; He X; Killeen ME; Fink MP
    Crit Care; 2009; 13(2):R55. PubMed ID: 19358737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improvement of therapeutic potential N-acetylcysteine in acetaminophen hepatotoxicity by encapsulation in PEGylated nano-niosomes.
    Firozian F; Karami S; Ranjbar A; Azandaryani MT; Nili-Ahmadabadi A
    Life Sci; 2020 Aug; 255():117832. PubMed ID: 32450164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparative evaluation of N-acetylcysteine and N-acetylcysteineamide in acetaminophen-induced hepatotoxicity in human hepatoma HepaRG cells.
    Tobwala S; Khayyat A; Fan W; Ercal N
    Exp Biol Med (Maywood); 2015 Feb; 240(2):261-72. PubMed ID: 25245075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acetaminophen psi parameter: a useful tool to quantify hepatotoxicity risk in acute acetaminophen overdose.
    Chomchai S; Chomchai C; Anusornsuwan T
    Clin Toxicol (Phila); 2011 Aug; 49(7):664-7. PubMed ID: 21819286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A metabolomic analysis of thiol response for standard and modified N-acetyl cysteine treatment regimens in patients with acetaminophen overdose.
    Dear JW; Ng ML; Bateman DN; Leroy Sivappiragasam P; Choi H; Khoo BBJ; Ibrahim B; Drum CL
    Clin Transl Sci; 2021 Jul; 14(4):1476-1489. PubMed ID: 33742775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients.
    Jaeschke H
    Dig Dis; 2015; 33(4):464-71. PubMed ID: 26159260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.