251 related articles for article (PubMed ID: 34985783)
1. Pharmacological CDK4/6 inhibition reveals a p53-dependent senescent state with restricted toxicity.
Wang B; Varela-Eirin M; Brandenburg SM; Hernandez-Segura A; van Vliet T; Jongbloed EM; Wilting SM; Ohtani N; Jager A; Demaria M
EMBO J; 2022 Mar; 41(6):e108946. PubMed ID: 34985783
[TBL] [Abstract][Full Text] [Related]
2. Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth.
Guan X; LaPak KM; Hennessey RC; Yu CY; Shakya R; Zhang J; Burd CE
Mol Cancer Res; 2017 Mar; 15(3):237-249. PubMed ID: 28039358
[TBL] [Abstract][Full Text] [Related]
3. CDK4/6 inhibitors induce breast cancer senescence with enhanced anti-tumor immunogenic properties compared with DNA-damaging agents.
Lee DH; Imran M; Choi JH; Park YJ; Kim YH; Min S; Park TJ; Choi YW
Mol Oncol; 2024 Jan; 18(1):216-232. PubMed ID: 37854019
[TBL] [Abstract][Full Text] [Related]
4. Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence.
Brookes S; Gagrica S; Sanij E; Rowe J; Gregory FJ; Hara E; Peters G
Cell Cycle; 2015; 14(8):1164-73. PubMed ID: 25695870
[TBL] [Abstract][Full Text] [Related]
5. Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors.
Patel HK; Tao N; Lee KM; Huerta M; Arlt H; Mullarkey T; Troy S; Arteaga CL; Bihani T
Breast Cancer Res; 2019 Dec; 21(1):146. PubMed ID: 31852484
[TBL] [Abstract][Full Text] [Related]
6. Senescence as a therapeutically relevant response to CDK4/6 inhibitors.
Wagner V; Gil J
Oncogene; 2020 Jul; 39(29):5165-5176. PubMed ID: 32541838
[TBL] [Abstract][Full Text] [Related]
7. Cellular senescence in the response of HR
Klapp V; Buqué A; Bloy N; Sato A; Yamazaki T; Zhou XK; Formenti SC; Galluzzi L; Petroni G
J Transl Med; 2023 Feb; 21(1):110. PubMed ID: 36765430
[TBL] [Abstract][Full Text] [Related]
8. Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.
Strzeszewska A; Alster O; Mosieniak G; Ciolko A; Sikora E
Cell Death Dis; 2018 Jan; 9(2):44. PubMed ID: 29352261
[TBL] [Abstract][Full Text] [Related]
9. Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway.
Sun X; Shi B; Zheng H; Min L; Yang J; Li X; Liao X; Huang W; Zhang M; Xu S; Zhu Z; Cui H; Liu X
Cell Death Dis; 2018 Feb; 9(3):260. PubMed ID: 29449532
[TBL] [Abstract][Full Text] [Related]
10. NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.
Raynard C; Ma X; Huna A; Tessier N; Massemin A; Zhu K; Flaman JM; Moulin F; Goehrig D; Medard JJ; Vindrieux D; Treilleux I; Hernandez-Vargas H; Ducreux S; Martin N; Bernard D
Aging Cell; 2022 Jul; 21(7):e13632. PubMed ID: 35653631
[TBL] [Abstract][Full Text] [Related]
11. Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.
Vilgelm AE; Johnson CA; Prasad N; Yang J; Chen SC; Ayers GD; Pawlikowski JS; Raman D; Sosman JA; Kelley M; Ecsedy JA; Shyr Y; Levy SE; Richmond A
J Natl Cancer Inst; 2016 Jun; 108(6):djv406. PubMed ID: 26719346
[TBL] [Abstract][Full Text] [Related]
12. Punicalagin induces senescent growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway.
Cheng X; Yao X; Xu S; Pan J; Yu H; Bao J; Guan H; Lu R; Zhang L
Biomed Pharmacother; 2018 Jul; 103():490-498. PubMed ID: 29677534
[TBL] [Abstract][Full Text] [Related]
13. Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP).
Salminen A; Kauppinen A; Kaarniranta K
Cell Signal; 2012 Apr; 24(4):835-45. PubMed ID: 22182507
[TBL] [Abstract][Full Text] [Related]
14. Membrane-Bound CD40L Promotes Senescence and Initiates Senescence-Associated Secretory Phenotype via NF-κB Activation in Lung Adenocarcinoma.
Xu W; Li Y; Yuan WW; Yin Y; Song WW; Wang Y; Huang QQ; Zhao WH; Wu JQ
Cell Physiol Biochem; 2018; 48(4):1793-1803. PubMed ID: 30078020
[TBL] [Abstract][Full Text] [Related]
15. Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.
Chien Y; Scuoppo C; Wang X; Fang X; Balgley B; Bolden JE; Premsrirut P; Luo W; Chicas A; Lee CS; Kogan SC; Lowe SW
Genes Dev; 2011 Oct; 25(20):2125-36. PubMed ID: 21979375
[TBL] [Abstract][Full Text] [Related]
16. Practical Treatment Strategies and Future Directions After Progression While Receiving CDK4/6 Inhibition and Endocrine Therapy in Advanced HR
Sammons S; Shastry M; Dent S; Anders C; Hamilton E
Clin Breast Cancer; 2020 Feb; 20(1):1-11. PubMed ID: 31780379
[TBL] [Abstract][Full Text] [Related]
17. Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor-induced senescence in breast cancer cells.
Kartika ID; Kotani H; Iida Y; Koyanagi A; Tanino R; Harada M
Cancer Med; 2021 Dec; 10(24):8988-8999. PubMed ID: 34761877
[TBL] [Abstract][Full Text] [Related]
18. Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype.
Coppé JP; Rodier F; Patil CK; Freund A; Desprez PY; Campisi J
J Biol Chem; 2011 Oct; 286(42):36396-403. PubMed ID: 21880712
[TBL] [Abstract][Full Text] [Related]
19. MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Vilgelm AE; Saleh N; Shattuck-Brandt R; Riemenschneider K; Slesur L; Chen SC; Johnson CA; Yang J; Blevins A; Yan C; Johnson DB; Al-Rohil RN; Halilovic E; Kauffmann RM; Kelley M; Ayers GD; Richmond A
Sci Transl Med; 2019 Aug; 11(505):. PubMed ID: 31413145
[TBL] [Abstract][Full Text] [Related]
20. AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop.
Han X; Zhang T; Zhang X; Zhang R; Lao K; Mi Y; Gou X
Mech Ageing Dev; 2020 Oct; 191():111347. PubMed ID: 32882228
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
