These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 34992268)

  • 1. Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies.
    Lopes KP; Snijders GJL; Humphrey J; Allan A; Sneeboer MAM; Navarro E; Schilder BM; Vialle RA; Parks M; Missall R; van Zuiden W; Gigase FAJ; Kübler R; van Berlekom AB; Hicks EM; Bӧttcher C; Priller J; Kahn RS; de Witte LD; Raj T
    Nat Genet; 2022 Jan; 54(1):4-17. PubMed ID: 34992268
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
    Raj T; Li YI; Wong G; Humphrey J; Wang M; Ramdhani S; Wang YC; Ng B; Gupta I; Haroutunian V; Schadt EE; Young-Pearse T; Mostafavi S; Zhang B; Sklar P; Bennett DA; De Jager PL
    Nat Genet; 2018 Nov; 50(11):1584-1592. PubMed ID: 30297968
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.
    Bonham LW; Sirkis DW; Yokoyama JS
    Front Immunol; 2019; 10():1170. PubMed ID: 31214167
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A transcriptomic atlas of aged human microglia.
    Olah M; Patrick E; Villani AC; Xu J; White CC; Ryan KJ; Piehowski P; Kapasi A; Nejad P; Cimpean M; Connor S; Yung CJ; Frangieh M; McHenry A; Elyaman W; Petyuk V; Schneider JA; Bennett DA; De Jager PL; Bradshaw EM
    Nat Commun; 2018 Feb; 9(1):539. PubMed ID: 29416036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional profiling in microglia across physiological and pathological states identifies a transcriptional module associated with neurodegeneration.
    Guvenek A; Parikshak N; Zamolodchikov D; Gelfman S; Moscati A; Dobbyn L; Stahl E; Shuldiner A; Coppola G
    Commun Biol; 2024 Sep; 7(1):1168. PubMed ID: 39294270
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
    Felsky D; Patrick E; Schneider JA; Mostafavi S; Gaiteri C; Patsopoulos N; Bennett DA; De Jager PL
    Mol Neurodegener; 2018 Jul; 13(1):38. PubMed ID: 30041668
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease.
    Morabito S; Miyoshi E; Michael N; Swarup V
    Hum Mol Genet; 2020 Oct; 29(17):2899-2919. PubMed ID: 32803238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A core transcriptional signature of human microglia: Derivation and utility in describing region-dependent alterations associated with Alzheimer's disease.
    Patir A; Shih B; McColl BW; Freeman TC
    Glia; 2019 Jul; 67(7):1240-1253. PubMed ID: 30758077
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
    Sudwarts A; Ramesha S; Gao T; Ponnusamy M; Wang S; Hansen M; Kozlova A; Bitarafan S; Kumar P; Beaulieu-Abdelahad D; Zhang X; Collier L; Szekeres C; Wood LB; Duan J; Thinakaran G; Rangaraju S
    Mol Neurodegener; 2022 May; 17(1):33. PubMed ID: 35526014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12.
    Sepulveda J; Kim JY; Binder J; Vicini S; Rebeck GW
    Mol Neurodegener; 2024 Mar; 19(1):24. PubMed ID: 38468308
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
    Kosoy R; Fullard JF; Zeng B; Bendl J; Dong P; Rahman S; Kleopoulos SP; Shao Z; Girdhar K; Humphrey J; de Paiva Lopes K; Charney AW; Kopell BH; Raj T; Bennett D; Kellner CP; Haroutunian V; Hoffman GE; Roussos P
    Nat Genet; 2022 Aug; 54(8):1145-1154. PubMed ID: 35931864
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
    Rangaraju S; Dammer EB; Raza SA; Rathakrishnan P; Xiao H; Gao T; Duong DM; Pennington MW; Lah JJ; Seyfried NT; Levey AI
    Mol Neurodegener; 2018 May; 13(1):24. PubMed ID: 29784049
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptomic profiling of microglia and astrocytes throughout aging.
    Pan J; Ma N; Yu B; Zhang W; Wan J
    J Neuroinflammation; 2020 Apr; 17(1):97. PubMed ID: 32238175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microglial Senescence and Activation in Healthy Aging and Alzheimer's Disease: Systematic Review and Neuropathological Scoring.
    Malvaso A; Gatti A; Negro G; Calatozzolo C; Medici V; Poloni TE
    Cells; 2023 Dec; 12(24):. PubMed ID: 38132144
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains.
    Walker DG; Tang TM; Mendsaikhan A; Tooyama I; Serrano GE; Sue LI; Beach TG; Lue LF
    Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31968618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microglial TREM2 at the Intersection of Brain Aging and Alzheimer's Disease.
    Qu W; Li L
    Neuroscientist; 2023 Jun; 29(3):302-316. PubMed ID: 34470515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease.
    Sobue A; Komine O; Hara Y; Endo F; Mizoguchi H; Watanabe S; Murayama S; Saito T; Saido TC; Sahara N; Higuchi M; Ogi T; Yamanaka K
    Acta Neuropathol Commun; 2021 Jan; 9(1):1. PubMed ID: 33402227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.
    Streit WJ; Braak H; Xue QS; Bechmann I
    Acta Neuropathol; 2009 Oct; 118(4):475-85. PubMed ID: 19513731
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.
    Lopes KO; Sparks DL; Streit WJ
    Glia; 2008 Aug; 56(10):1048-60. PubMed ID: 18442088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.
    Mancuso R; Fattorelli N; Martinez-Muriana A; Davis E; Wolfs L; Van Den Daele J; Geric I; Premereur J; Polanco P; Bijnens B; Preman P; Serneels L; Poovathingal S; Balusu S; Verfaillie C; Fiers M; De Strooper B
    Nat Neurosci; 2024 May; 27(5):886-900. PubMed ID: 38539015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.