BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 34995376)

  • 1. TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation.
    Shiode Y; Kodama T; Shigeno S; Murai K; Tanaka S; Newberg JY; Kondo J; Kobayashi S; Yamada R; Hikita H; Sakamori R; Suemizu H; Tatsumi T; Eguchi H; Jenkins NA; Copeland NG; Takehara T
    Hepatology; 2023 Feb; 77(2):395-410. PubMed ID: 34995376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway.
    He JQ; Saha SK; Kang JR; Zarnegar B; Cheng G
    J Biol Chem; 2007 Feb; 282(6):3688-94. PubMed ID: 17158868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
    Wang J; Dong M; Xu Z; Song X; Zhang S; Qiao Y; Che L; Gordan J; Hu K; Liu Y; Calvisi DF; Chen X
    Oncogene; 2018 Jun; 37(24):3229-3242. PubMed ID: 29545603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
    Mu X; Pradere JP; Affò S; Dapito DH; Friedman R; Lefkovitch JH; Schwabe RF
    Gastroenterology; 2016 Mar; 150(3):720-33. PubMed ID: 26627606
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
    Liao G; Zhang M; Harhaj EW; Sun SC
    J Biol Chem; 2004 Jun; 279(25):26243-50. PubMed ID: 15084608
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma.
    Terada M; Horisawa K; Miura S; Takashima Y; Ohkawa Y; Sekiya S; Matsuda-Ito K; Suzuki A
    Sci Rep; 2016 Oct; 6():34691. PubMed ID: 27698452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injury.
    Jiang B; Shen H; Chen Z; Yin L; Zan L; Rui L
    J Biol Chem; 2015 May; 290(18):11704-14. PubMed ID: 25792747
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TRAF3 loss-of-function reveals the noncanonical NF-κB pathway as a therapeutic target in diffuse large B cell lymphoma.
    Li MY; Chong LC; Duns G; Lytle A; Woolcock B; Jiang A; Telenius A; Ben-Neriah S; Nawaz W; Slack GW; Elisia I; Viganò E; Aoki T; Healy S; Krystal G; Venturutti L; Scott DW; Steidl C
    Proc Natl Acad Sci U S A; 2024 Apr; 121(18):e2320421121. PubMed ID: 38662551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
    Zarnegar BJ; Wang Y; Mahoney DJ; Dempsey PW; Cheung HH; He J; Shiba T; Yang X; Yeh WC; Mak TW; Korneluk RG; Cheng G
    Nat Immunol; 2008 Dec; 9(12):1371-8. PubMed ID: 18997794
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Both amino- and carboxyl-terminal domains of TRAF3 negatively regulate NF-kappaB activation induced by OX40 signaling.
    Takaori-Kondo A; Hori T; Fukunaga K; Morita R; Kawamata S; Uchiyama T
    Biochem Biophys Res Commun; 2000 Jun; 272(3):856-63. PubMed ID: 10860842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways.
    Muro I; Fang G; Gardella KA; Mahajan IM; Wright CW
    Cell Cycle; 2014; 13(12):1918-27. PubMed ID: 24739416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor κB pathway and chemokine expression in human T cells.
    Michel M; Wilhelmi I; Schultz AS; Preussner M; Heyd F
    J Biol Chem; 2014 May; 289(19):13651-60. PubMed ID: 24671418
    [TBL] [Abstract][Full Text] [Related]  

  • 13. OTUD7B suppresses Smac mimetic-induced lung cancer cell invasion and migration via deubiquitinating TRAF3.
    Zhang B; Yang C; Wang R; Wu J; Zhang Y; Liu D; Sun X; Li X; Ren H; Qin S
    J Exp Clin Cancer Res; 2020 Nov; 39(1):244. PubMed ID: 33198776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TLR2 promotes human intrahepatic cholangiocarcinoma cell migration and invasion by modulating NF-κB pathway-mediated inflammatory responses.
    Liu B; Yan S; Jia Y; Ma J; Wu S; Xu Y; Shang M; Mao A
    FEBS J; 2016 Oct; 283(20):3839-3850. PubMed ID: 27616304
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Long non-coding RNA MEG3 represses cholangiocarcinoma by regulating miR-361-5p/TRAF3 axis.
    Lu WX
    Eur Rev Med Pharmacol Sci; 2019 Sep; 23(17):7356-7368. PubMed ID: 31539122
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NOTCH-YAP1/TEAD-DNMT1 Axis Drives Hepatocyte Reprogramming Into Intrahepatic Cholangiocarcinoma.
    Hu S; Molina L; Tao J; Liu S; Hassan M; Singh S; Poddar M; Bell A; Sia D; Oertel M; Raeman R; Nejak-Bowen K; Singhi A; Luo J; Monga SP; Ko S
    Gastroenterology; 2022 Aug; 163(2):449-465. PubMed ID: 35550144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
    Vallabhapurapu S; Matsuzawa A; Zhang W; Tseng PH; Keats JJ; Wang H; Vignali DA; Bergsagel PL; Karin M
    Nat Immunol; 2008 Dec; 9(12):1364-70. PubMed ID: 18997792
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes.
    Sekiya S; Suzuki A
    J Clin Invest; 2012 Nov; 122(11):3914-8. PubMed ID: 23023701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autocrine parathyroid hormone-like hormone promotes intrahepatic cholangiocarcinoma cell proliferation via increased ERK/JNK-ATF2-cyclinD1 signaling.
    Tang J; Liao Y; He S; Shi J; Peng L; Xu X; Xie F; Diao N; Huang J; Xie Q; Lin C; Luo X; Liao K; Ma J; Li J; Zhou D; Li Z; Xu J; Zhong C; Wang G; Bai L
    J Transl Med; 2017 Nov; 15(1):238. PubMed ID: 29178939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway.
    Shen J; Zhou Y; Zhang X; Peng W; Peng C; Zhou Q; Li C; Wen T; Shi Y
    Aging (Albany NY); 2019 Nov; 11(21):9280-9294. PubMed ID: 31689237
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.