BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 34996123)

  • 1. Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.
    Mundy C; Chung J; Koyama E; Bunting S; Mahimkar R; Pacifici M
    J Orthop Res; 2022 Oct; 40(10):2391-2401. PubMed ID: 34996123
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
    Sinha S; Mundy C; Bechtold T; Sgariglia F; Ibrahim MM; Billings PC; Carroll K; Koyama E; Jones KB; Pacifici M
    PLoS Genet; 2017 Apr; 13(4):e1006742. PubMed ID: 28445472
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.
    Pacifici M
    Matrix Biol; 2018 Oct; 71-72():28-39. PubMed ID: 29277722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Palovarotene Inhibits Osteochondroma Formation in a Mouse Model of Multiple Hereditary Exostoses.
    Inubushi T; Lemire I; Irie F; Yamaguchi Y
    J Bone Miner Res; 2018 Apr; 33(4):658-666. PubMed ID: 29120519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The short-lived exostosis induced surgically versus the lasting genetic hereditary multiple exostoses.
    Trebicz-Geffen M; Nevo Z; Evron Z; Posternak N; Glaser T; Fridkin M; Kollander Y; Robinson D
    Exp Mol Pathol; 2003 Feb; 74(1):40-8. PubMed ID: 12645631
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
    Matsumoto K; Irie F; Mackem S; Yamaguchi Y
    Proc Natl Acad Sci U S A; 2010 Jun; 107(24):10932-7. PubMed ID: 20534475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signaling systems affecting the severity of multiple osteochondromas.
    Piombo V; Jochmann K; Hoffmann D; Wuelling M; Vortkamp A
    Bone; 2018 Jun; 111():71-81. PubMed ID: 29545125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT.
    de Andrea CE; Reijnders CM; Kroon HM; de Jong D; Hogendoorn PC; Szuhai K; Bovée JV
    Oncogene; 2012 Mar; 31(9):1095-104. PubMed ID: 21804604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses.
    Huegel J; Sgariglia F; Enomoto-Iwamoto M; Koyama E; Dormans JP; Pacifici M
    Dev Dyn; 2013 Sep; 242(9):1021-32. PubMed ID: 23821404
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity.
    Cheung PK; McCormick C; Crawford BE; Esko JD; Tufaro F; Duncan G
    Am J Hum Genet; 2001 Jul; 69(1):55-66. PubMed ID: 11391482
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: a mechanism possibly involved in hereditary multiple exostoses.
    Huegel J; Enomoto-Iwamoto M; Sgariglia F; Koyama E; Pacifici M
    Am J Pathol; 2015 Jun; 185(6):1676-85. PubMed ID: 25863260
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Haploinsufficiency of EXT1 and Heparan Sulphate Deficiency Associated with Hereditary Multiple Exostoses in a Pakistani Family.
    Ajmal M; Muhammad H; Nasir M; Shoaib M; Malik SA; Ullah I
    Medicina (Kaunas); 2022 Dec; 59(1):. PubMed ID: 36676722
    [No Abstract]   [Full Text] [Related]  

  • 13. Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
    Huegel J; Mundy C; Sgariglia F; Nygren P; Billings PC; Yamaguchi Y; Koyama E; Pacifici M
    Dev Biol; 2013 May; 377(1):100-12. PubMed ID: 23458899
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dysplasia epiphysealis hemimelica (Trevor disease): a rare developmental disorder of bone mimicking osteochondroma of long bones.
    Glick R; Khaldi L; Ptaszynski K; Steiner GC
    Hum Pathol; 2007 Aug; 38(8):1265-72. PubMed ID: 17490719
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.
    Hameetman L; David G; Yavas A; White SJ; Taminiau AH; Cleton-Jansen AM; Hogendoorn PC; Bovée JV
    J Pathol; 2007 Mar; 211(4):399-409. PubMed ID: 17226760
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
    Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
    Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis.
    Sgariglia F; Pedrini E; Bradfield JP; Bhatti TR; D'Adamo P; Dormans JP; Gunawardena AT; Hakonarson H; Hecht JT; Sangiorgi L; Pacifici M; Enomoto-Iwamoto M; Grant SF
    Bone; 2015 Mar; 72():123-7. PubMed ID: 25498973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ext-mutation analysis in Italian sporadic and hereditary osteochondromas.
    Gigante M; Matera MG; Seripa D; Izzo AM; Venanzi R; Giannotti A; Digilio MC; Gravina C; Lazzari M; Monteleone G; Monteleone M; Dallapiccola B; Fazio VM
    Int J Cancer; 2001 Nov; 95(6):378-83. PubMed ID: 11668521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.
    Pacifici M
    Curr Osteoporos Rep; 2017 Jun; 15(3):142-152. PubMed ID: 28466453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice.
    Morimoto K; Shimizu T; Furukawa K; Morio H; Kurosawa H; Shirasawa T
    Biochem Biophys Res Commun; 2002 Apr; 292(4):999-1009. PubMed ID: 11944914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.