203 related articles for article (PubMed ID: 34999054)
1. Identification of ritanserin analogs that display DGK isoform specificity.
Granade ME; Manigat LC; Lemke MC; Purow BW; Harris TE
Biochem Pharmacol; 2022 Mar; 197():114908. PubMed ID: 34999054
[TBL] [Abstract][Full Text] [Related]
2. Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists.
Boroda S; Niccum M; Raje V; Purow BW; Harris TE
Biochem Pharmacol; 2017 Jan; 123():29-39. PubMed ID: 27974147
[TBL] [Abstract][Full Text] [Related]
3. Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics.
McCloud RL; Franks CE; Campbell ST; Purow BW; Harris TE; Hsu KL
Biochemistry; 2018 Jan; 57(2):231-236. PubMed ID: 29155586
[TBL] [Abstract][Full Text] [Related]
4. Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Olmez I; Love S; Xiao A; Manigat L; Randolph P; McKenna BD; Neal BP; Boroda S; Li M; Brenneman B; Abounader R; Floyd D; Lee J; Nakano I; Godlewski J; Bronisz A; Sulman EP; Mayo M; Gioeli D; Weber M; Harris TE; Purow B
Neuro Oncol; 2018 Jan; 20(2):192-202. PubMed ID: 29048560
[TBL] [Abstract][Full Text] [Related]
5. Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signals.
Arranz-Nicolás J; Ogando J; Soutar D; Arcos-Pérez R; Meraviglia-Crivelli D; Mañes S; Mérida I; Ávila-Flores A
Cancer Immunol Immunother; 2018 Jun; 67(6):965-980. PubMed ID: 29572701
[TBL] [Abstract][Full Text] [Related]
6. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response.
Liu K; Kunii N; Sakuma M; Yamaki A; Mizuno S; Sato M; Sakai H; Kado S; Kumagai K; Kojima H; Okabe T; Nagano T; Shirai Y; Sakane F
J Lipid Res; 2016 Mar; 57(3):368-79. PubMed ID: 26768655
[TBL] [Abstract][Full Text] [Related]
7. Diacylglycerol kinase α-selective inhibitors induce apoptosis and reduce viability of melanoma and several other cancer cell lines.
Yamaki A; Akiyama R; Murakami C; Takao S; Murakami Y; Mizuno S; Takahashi D; Kado S; Taketomi A; Shirai Y; Goto K; Sakane F
J Cell Biochem; 2019 Jun; 120(6):10043-10056. PubMed ID: 30536880
[TBL] [Abstract][Full Text] [Related]
8. The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling.
Joshi RP; Schmidt AM; Das J; Pytel D; Riese MJ; Lester M; Diehl JA; Behrens EM; Kambayashi T; Koretzky GA
Sci Signal; 2013 Nov; 6(303):ra102. PubMed ID: 24280043
[TBL] [Abstract][Full Text] [Related]
9. Palmitic acid- and/or palmitoleic acid-containing phosphatidic acids are generated by diacylglycerol kinase α in starved Jurkat T cells.
Murakami Y; Murakami C; Hoshino F; Lu Q; Akiyama R; Yamaki A; Takahashi D; Sakane F
Biochem Biophys Res Commun; 2020 May; 525(4):1054-1060. PubMed ID: 32184022
[TBL] [Abstract][Full Text] [Related]
10. Fatty acids inhibit growth-factor-induced diacylglycerol kinase alpha activation in vascular smooth-muscle cells.
Du X; Jiang Y; Qian W; Lu X; Walsh JP
Biochem J; 2001 Jul; 357(Pt 1):275-82. PubMed ID: 11415460
[TBL] [Abstract][Full Text] [Related]
11. Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening.
Velnati S; Ruffo E; Massarotti A; Talmon M; Varma KSS; Gesu A; Fresu LG; Snow AL; Bertoni A; Capello D; Tron GC; Graziani A; Baldanzi G
Eur J Med Chem; 2019 Feb; 164():378-390. PubMed ID: 30611057
[TBL] [Abstract][Full Text] [Related]
12. Screening of subtype-specific activators and inhibitors for diacylglycerol kinase.
Hayashi D; Tsumagari R; Liu K; Ueda S; Yamanoue M; Sakane F; Shirai Y
J Biochem; 2019 Jun; 165(6):517-522. PubMed ID: 30715374
[TBL] [Abstract][Full Text] [Related]
13. Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes.
Jiang Y; Sakane F; Kanoh H; Walsh JP
Biochem Pharmacol; 2000 Apr; 59(7):763-72. PubMed ID: 10718334
[TBL] [Abstract][Full Text] [Related]
14. Molecular Pathways: Targeting Diacylglycerol Kinase Alpha in Cancer.
Purow B
Clin Cancer Res; 2015 Nov; 21(22):5008-12. PubMed ID: 26420856
[TBL] [Abstract][Full Text] [Related]
15. The Ligand Binding Landscape of Diacylglycerol Kinases.
Franks CE; Campbell ST; Purow BW; Harris TE; Hsu KL
Cell Chem Biol; 2017 Jul; 24(7):870-880.e5. PubMed ID: 28712745
[TBL] [Abstract][Full Text] [Related]
16. Depression of type I diacylglycerol kinases in pancreatic β-cells from male mice results in impaired insulin secretion.
Kurohane Kaneko Y; Kobayashi Y; Motoki K; Nakata K; Miyagawa S; Yamamoto M; Hayashi D; Shirai Y; Sakane F; Ishikawa T
Endocrinology; 2013 Nov; 154(11):4089-98. PubMed ID: 24035999
[TBL] [Abstract][Full Text] [Related]
17. Diacylglycerol kinase alpha activity promotes survival of CD4+ 8+ double positive cells during thymocyte development.
Outram SV; Crompton T; Merida I; Varas A; Martinez-A C
Immunology; 2002 Apr; 105(4):391-8. PubMed ID: 11985659
[TBL] [Abstract][Full Text] [Related]
18. Combined inhibition/silencing of diacylglycerol kinase α and ζ simultaneously and synergistically enhances interleukin-2 production in T cells and induces cell death of melanoma cells.
Takao S; Akiyama R; Sakane F
J Cell Biochem; 2021 May; 122(5):494-506. PubMed ID: 33399248
[TBL] [Abstract][Full Text] [Related]
19. Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Manigat LC; Granade ME; Taori S; Miller CA; Vass LR; Zhong XP; Harris TE; Purow BW
Front Immunol; 2021; 12():722469. PubMed ID: 34804012
[TBL] [Abstract][Full Text] [Related]
20. Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling.
Sharma P; Yadav SK; Shah SD; Javed E; Lim JM; Pan S; Nayak AP; Panettieri RA; Penn RB; Kambayashi T; Deshpande DA
Am J Respir Cell Mol Biol; 2021 Dec; 65(6):658-671. PubMed ID: 34293268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
