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2. The effect of amino acid substitutions at position 342 on the secretion of human alpha 1-antitrypsin from Xenopus oocytes. Wu Y; Foreman RC FEBS Lett; 1990 Jul; 268(1):21-3. PubMed ID: 2384157 [TBL] [Abstract][Full Text] [Related]
3. Xenopus oocytes can synthesise but do not secrete the Z variant of human alpha 1-antitrypsin. Foreman RC; Judah JD; Colman A FEBS Lett; 1984 Mar; 168(1):84-8. PubMed ID: 6200362 [TBL] [Abstract][Full Text] [Related]
4. Mutations which impede loop/sheet polymerization enhance the secretion of human alpha 1-antitrypsin deficiency variants. Sidhar SK; Lomas DA; Carrell RW; Foreman RC J Biol Chem; 1995 Apr; 270(15):8393-6. PubMed ID: 7721731 [TBL] [Abstract][Full Text] [Related]
5. Disruption of the Lys-290--Glu-342 salt bridge in human alpha 1-antitrypsin does not prevent its synthesis and secretion. Foreman RC FEBS Lett; 1987 May; 216(1):79-82. PubMed ID: 2884131 [TBL] [Abstract][Full Text] [Related]
6. Repair of the secretion defect in the Z form of alpha 1-antitrypsin by addition of a second mutation. Brantly M; Courtney M; Crystal RG Science; 1988 Dec; 242(4886):1700-2. PubMed ID: 2904702 [TBL] [Abstract][Full Text] [Related]
7. The Recruitment-Secretory Block ("R-SB") Phenomenon and Endoplasmic Reticulum Storage Diseases. Callea F; Tomà P; Bellacchio E Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34202771 [TBL] [Abstract][Full Text] [Related]
8. Disruption of the 290-342 salt bridge is not responsible for the secretory defect of the PiZ alpha 1-antitrypsin variant. Sifers RN; Hardick CP; Woo SL J Biol Chem; 1989 Feb; 264(5):2997-3001. PubMed ID: 2563374 [TBL] [Abstract][Full Text] [Related]
9. The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Lomas DA; Evans DL; Finch JT; Carrell RW Nature; 1992 Jun; 357(6379):605-7. PubMed ID: 1608473 [TBL] [Abstract][Full Text] [Related]
10. Human alpha 1-antitrypsin expression in Xenopus oocytes. Secretion of the normal (PiM) and abnormal (PiZ) forms. Errington DM; Bathurst IC; Carrell RW Eur J Biochem; 1985 Dec; 153(2):361-5. PubMed ID: 3878282 [TBL] [Abstract][Full Text] [Related]
11. The endoplasmic reticulum degradation pathway for mutant secretory proteins alpha1-antitrypsin Z and S is distinct from that for an unassembled membrane protein. Teckman JH; Perlmutter DH J Biol Chem; 1996 May; 271(22):13215-20. PubMed ID: 8662752 [TBL] [Abstract][Full Text] [Related]
12. Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants. Ronzoni R; Berardelli R; Medicina D; Sitia R; Gooptu B; Fra AM Hum Mol Genet; 2016 Feb; 25(4):642-50. PubMed ID: 26647313 [TBL] [Abstract][Full Text] [Related]
13. Alpha-1-antitrypsin deficiency: accumulation or degradation of mutant variants within the hepatic endoplasmic reticulum. Sifers RN; Finegold MJ; Woo SL Am J Respir Cell Mol Biol; 1989 Nov; 1(5):341-5. PubMed ID: 2700304 [TBL] [Abstract][Full Text] [Related]
14. A selective defect in secretion of alpha 1-proteinase inhibitor PiZZ demonstrated in surrogate and primary extrahepatic cell culture. Perlmutter DH; Kay RM; Cole FS; Rossing TH; Van Thiel D; Colten HR Trans Assoc Am Physicians; 1985; 98():47-54. PubMed ID: 3879845 [No Abstract] [Full Text] [Related]
15. Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. Gooptu B; Miranda E; Nobeli I; Mallya M; Purkiss A; Brown SC; Summers C; Phillips RL; Lomas DA; Barrett TE J Mol Biol; 2009 Apr; 387(4):857-68. PubMed ID: 19232354 [TBL] [Abstract][Full Text] [Related]