225 related articles for article (PubMed ID: 34999833)
1. Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex.
Terry BK; Park R; Cho SH; Crino PB; Kim S
Hum Mol Genet; 2022 Jun; 31(12):1979-1996. PubMed ID: 34999833
[TBL] [Abstract][Full Text] [Related]
2. Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.
Way SW; McKenna J; Mietzsch U; Reith RM; Wu HC; Gambello MJ
Hum Mol Genet; 2009 Apr; 18(7):1252-65. PubMed ID: 19150975
[TBL] [Abstract][Full Text] [Related]
3. Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.
Carson RP; Van Nielen DL; Winzenburger PA; Ess KC
Neurobiol Dis; 2012 Jan; 45(1):369-80. PubMed ID: 21907282
[TBL] [Abstract][Full Text] [Related]
4. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
[TBL] [Abstract][Full Text] [Related]
5. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
Zhang B; Zou J; Han L; Beeler B; Friedman JL; Griffin E; Piao YS; Rensing NR; Wong M
Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
[TBL] [Abstract][Full Text] [Related]
6. The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.
Schrötter S; Yuskaitis CJ; MacArthur MR; Mitchell SJ; Hosios AM; Osipovich M; Torrence ME; Mitchell JR; Hoxhaj G; Sahin M; Manning BD
Cell Rep; 2022 May; 39(7):110824. PubMed ID: 35584673
[TBL] [Abstract][Full Text] [Related]
7. Biallelic Mutations in
Winden KD; Sundberg M; Yang C; Wafa SMA; Dwyer S; Chen PF; Buttermore ED; Sahin M
J Neurosci; 2019 Nov; 39(47):9294-9305. PubMed ID: 31591157
[TBL] [Abstract][Full Text] [Related]
8. Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca
Hisatsune C; Shimada T; Miyamoto A; Lee A; Yamagata K
J Neurosci; 2021 Sep; 41(39):8134-8149. PubMed ID: 34417327
[TBL] [Abstract][Full Text] [Related]
9. Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.
Parkhitko A; Myachina F; Morrison TA; Hindi KM; Auricchio N; Karbowniczek M; Wu JJ; Finkel T; Kwiatkowski DJ; Yu JJ; Henske EP
Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12455-60. PubMed ID: 21746920
[TBL] [Abstract][Full Text] [Related]
10. Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
McKenna J; Kapfhamer D; Kinchen JM; Wasek B; Dunworth M; Murray-Stewart T; Bottiglieri T; Casero RA; Gambello MJ
Hum Mol Genet; 2018 Jun; 27(12):2113-2124. PubMed ID: 29635516
[TBL] [Abstract][Full Text] [Related]
11. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.
Liang N; Zhang C; Dill P; Panasyuk G; Pion D; Koka V; Gallazzini M; Olson EN; Lam H; Henske EP; Dong Z; Apte U; Pallet N; Johnson RL; Terzi F; Kwiatkowski DJ; Scoazec JY; Martignoni G; Pende M
J Exp Med; 2014 Oct; 211(11):2249-63. PubMed ID: 25288394
[TBL] [Abstract][Full Text] [Related]
12. Sirolimus relieves seizures and neuropsychiatric symptoms via changes of microglial polarity in tuberous sclerosis complex model mice.
Koike-Kumagai M; Fujimoto M; Wataya-Kaneda M
Neuropharmacology; 2022 Nov; 218():109203. PubMed ID: 35931213
[TBL] [Abstract][Full Text] [Related]
13. A Farnesyltransferase Inhibitor Restores Cognitive Deficits in
Sugiura H; Shimada T; Moriya-Ito K; Goto JI; Fujiwara H; Ishii R; Shitara H; Taya C; Fujii S; Kobayashi T; Hino O; Worley PF; Yamagata K
J Neurosci; 2022 Mar; 42(12):2598-2612. PubMed ID: 35121635
[TBL] [Abstract][Full Text] [Related]
14. Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways.
Pal R; Xiong Y; Sardiello M
Proc Natl Acad Sci U S A; 2019 Feb; 116(8):2977-2986. PubMed ID: 30728291
[TBL] [Abstract][Full Text] [Related]
15. mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.
Peng H; Liu J; Sun Q; Chen R; Wang Y; Duan J; Li C; Li B; Jing Y; Chen X; Mao Q; Xu KF; Walker CL; Li J; Wang J; Zhang H
Oncogene; 2013 Sep; 32(39):4702-11. PubMed ID: 23108404
[TBL] [Abstract][Full Text] [Related]
16. Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Haji N; Riebe I; Aguilar-Valles A; Artinian J; Laplante I; Lacaille JC
Mol Autism; 2020 May; 11(1):29. PubMed ID: 32375878
[TBL] [Abstract][Full Text] [Related]
17. Loss of the tuberous sclerosis complex protein tuberin causes Purkinje cell degeneration.
Reith RM; Way S; McKenna J; Haines K; Gambello MJ
Neurobiol Dis; 2011 Jul; 43(1):113-22. PubMed ID: 21419848
[TBL] [Abstract][Full Text] [Related]
18. Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment.
Mills JD; Iyer AM; van Scheppingen J; Bongaarts A; Anink JJ; Janssen B; Zimmer TS; Spliet WG; van Rijen PC; Jansen FE; Feucht M; Hainfellner JA; Krsek P; Zamecnik J; Kotulska K; Jozwiak S; Jansen A; Lagae L; Curatolo P; Kwiatkowski DJ; Pasterkamp RJ; Senthilkumar K; von Oerthel L; Hoekman MF; Gorter JA; Crino PB; Mühlebner A; Scicluna BP; Aronica E
Sci Rep; 2017 Aug; 7(1):8089. PubMed ID: 28808237
[TBL] [Abstract][Full Text] [Related]
19. TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.
Ogórek B; Lam HC; Khabibullin D; Liu HJ; Nijmeh J; Triboulet R; Kwiatkowski DJ; Gregory RI; Henske EP
Hum Mol Genet; 2018 May; 27(9):1654-1663. PubMed ID: 29509898
[TBL] [Abstract][Full Text] [Related]
20. Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
Meikle L; Pollizzi K; Egnor A; Kramvis I; Lane H; Sahin M; Kwiatkowski DJ
J Neurosci; 2008 May; 28(21):5422-32. PubMed ID: 18495876
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
