200 related articles for article (PubMed ID: 35021081)
1. 2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity.
Kusi M; Zand M; Lin LL; Chen M; Lopez A; Lin CL; Wang CM; Lucio ND; Kirma NB; Ruan J; Huang TH; Mitsuya K
Cell Rep; 2022 Jan; 38(2):110220. PubMed ID: 35021081
[TBL] [Abstract][Full Text] [Related]
2. MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Terunuma A; Putluri N; Mishra P; Mathé EA; Dorsey TH; Yi M; Wallace TA; Issaq HJ; Zhou M; Killian JK; Stevenson HS; Karoly ED; Chan K; Samanta S; Prieto D; Hsu TY; Kurley SJ; Putluri V; Sonavane R; Edelman DC; Wulff J; Starks AM; Yang Y; Kittles RA; Yfantis HG; Lee DH; Ioffe OB; Schiff R; Stephens RM; Meltzer PS; Veenstra TD; Westbrook TF; Sreekumar A; Ambs S
J Clin Invest; 2014 Jan; 124(1):398-412. PubMed ID: 24316975
[TBL] [Abstract][Full Text] [Related]
3. Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.
Brinkley G; Nam H; Shim E; Kirkman R; Kundu A; Karki S; Heidarian Y; Tennessen JM; Liu J; Locasale JW; Guo T; Wei S; Gordetsky J; Johnson-Pais TL; Absher D; Rakheja D; Challa AK; Sudarshan S
Dis Model Mech; 2020 Nov; 13(11):. PubMed ID: 32928875
[TBL] [Abstract][Full Text] [Related]
4. Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth.
Li H; Chawla G; Hurlburt AJ; Sterrett MC; Zaslaver O; Cox J; Karty JA; Rosebrock AP; Caudy AA; Tennessen JM
Proc Natl Acad Sci U S A; 2017 Feb; 114(6):1353-1358. PubMed ID: 28115720
[TBL] [Abstract][Full Text] [Related]
5. ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.
Mishra P; Tang W; Putluri V; Dorsey TH; Jin F; Wang F; Zhu D; Amable L; Deng T; Zhang S; Killian JK; Wang Y; Minas TZ; Yfantis HG; Lee DH; Sreekumar A; Bustin M; Liu W; Putluri N; Ambs S
J Clin Invest; 2018 Jan; 128(1):323-340. PubMed ID: 29202474
[TBL] [Abstract][Full Text] [Related]
6. 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation.
Schvartzman JM; Reuter VP; Koche RP; Thompson CB
Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12851-12856. PubMed ID: 31182575
[TBL] [Abstract][Full Text] [Related]
7. L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.
Shim EH; Livi CB; Rakheja D; Tan J; Benson D; Parekh V; Kho EY; Ghosh AP; Kirkman R; Velu S; Dutta S; Chenna B; Rea SL; Mishur RJ; Li Q; Johnson-Pais TL; Guo L; Bae S; Wei S; Block K; Sudarshan S
Cancer Discov; 2014 Nov; 4(11):1290-8. PubMed ID: 25182153
[TBL] [Abstract][Full Text] [Related]
8. IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C; Ward PS; Kapoor GS; Rohle D; Turcan S; Abdel-Wahab O; Edwards CR; Khanin R; Figueroa ME; Melnick A; Wellen KE; O'Rourke DM; Berger SL; Chan TA; Levine RL; Mellinghoff IK; Thompson CB
Nature; 2012 Feb; 483(7390):474-8. PubMed ID: 22343901
[TBL] [Abstract][Full Text] [Related]
9. Quantitative Analysis of Oncometabolite 2-Hydroxyglutarate.
Yuan BF
Adv Exp Med Biol; 2021; 1280():161-172. PubMed ID: 33791981
[TBL] [Abstract][Full Text] [Related]
10. Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.
Fan J; Teng X; Liu L; Mattaini KR; Looper RE; Vander Heiden MG; Rabinowitz JD
ACS Chem Biol; 2015 Feb; 10(2):510-6. PubMed ID: 25406093
[TBL] [Abstract][Full Text] [Related]
11. Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation.
Taub M; Mahmoudzadeh NH; Tennessen JM; Sudarshan S
Front Endocrinol (Lausanne); 2022; 13():932286. PubMed ID: 36133305
[TBL] [Abstract][Full Text] [Related]
12. Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.
Colvin H; Nishida N; Konno M; Haraguchi N; Takahashi H; Nishimura J; Hata T; Kawamoto K; Asai A; Tsunekuni K; Koseki J; Mizushima T; Satoh T; Doki Y; Mori M; Ishii H
Sci Rep; 2016 Nov; 6():36289. PubMed ID: 27824159
[TBL] [Abstract][Full Text] [Related]
13. The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function.
Foskolou IP; Cunha PP; Sánchez-López E; Minogue EA; Nicolet BP; Guislain A; Jorgensen C; Kostidis S; Zandhuis ND; Barbieri L; Bargiela D; Nathanael D; Tyrakis PA; Palazon A; Giera M; Wolkers MC; Johnson RS
Cell Rep; 2023 Sep; 42(9):113013. PubMed ID: 37632752
[TBL] [Abstract][Full Text] [Related]
14. Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma.
de la Fuente MI; Young RJ; Rubel J; Rosenblum M; Tisnado J; Briggs S; Arevalo-Perez J; Cross JR; Campos C; Straley K; Zhu D; Dong C; Thomas A; Omuro AA; Nolan CP; Pentsova E; Kaley TJ; Oh JH; Noeske R; Maher E; Choi C; Gutin PH; Holodny AI; Yen K; DeAngelis LM; Mellinghoff IK; Thakur SB
Neuro Oncol; 2016 Feb; 18(2):283-90. PubMed ID: 26691210
[TBL] [Abstract][Full Text] [Related]
15. Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
Becker-Kettern J; Paczia N; Conrotte JF; Kay DP; Guignard C; Jung PP; Linster CL
J Biol Chem; 2016 Mar; 291(12):6036-58. PubMed ID: 26774271
[TBL] [Abstract][Full Text] [Related]
16. Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells.
Li L; Paz AC; Wilky BA; Johnson B; Galoian K; Rosenberg A; Hu G; Tinoco G; Bodamer O; Trent JC
PLoS One; 2015; 10(9):e0133813. PubMed ID: 26368816
[TBL] [Abstract][Full Text] [Related]
17. Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.
Jin G; Reitman ZJ; Duncan CG; Spasojevic I; Gooden DM; Rasheed BA; Yang R; Lopez GY; He Y; McLendon RE; Bigner DD; Yan H
Cancer Res; 2013 Jan; 73(2):496-501. PubMed ID: 23204232
[TBL] [Abstract][Full Text] [Related]
18. The oncometabolite L-2-hydroxyglutarate is a common product of dipteran larval development.
Mahmoudzadeh NH; Fitt AJ; Schwab DB; Martenis WE; Nease LM; Owings CG; Brinkley GJ; Li H; Karty JA; Sudarshan S; Hardy RW; Moczek AP; Picard CJ; Tennessen JM
Insect Biochem Mol Biol; 2020 Dec; 127():103493. PubMed ID: 33157229
[TBL] [Abstract][Full Text] [Related]
19. The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation.
Liu L; Hu K; Feng J; Wang H; Fu S; Wang B; Wang L; Xu Y; Yu X; Huang H
BMC Cancer; 2021 Jan; 21(1):36. PubMed ID: 33413208
[TBL] [Abstract][Full Text] [Related]
20. A
Li H; Hurlburt AJ; Tennessen JM
Dis Model Mech; 2018 Sep; 11(9):. PubMed ID: 30108060
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]